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Proteins/UNIPROT:O43148
Catalytic subunit of the mRNA-capping methyltransferase RNMT:RAMAC complex that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs. Binds RNA containing 5'-terminal GpppC..
Function from UniProtKB (O43148), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
124 statements
124 statements · 3 reference databases · Subject: RNMT · Sources: Hetionet, Reactome, WikiPathways
2 reactions
MAM01864c+S-adenosyl-L-methionineMAM02438c+CHEBI:16680
Catalysed by RNMT
Reaction pageReversibleBalance undeterminableEC 2.1.1.56cytosol
Human-GEM MAR09509CC BY 4.0Reference data
a 5'-end (5'-triphosphoguanosine)-ribonucleoside in mRNA+S-adenosyl-L-methioninea 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA+S-adenosyl-L-homocysteine
Catalysed by RNMT
Reaction pageDirection not assertedBalance undeterminable
8 names
Resolves to: RNMT