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Proteins/UNIPROT:P54819
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis..
Function from UniProtKB (P54819), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
141 statements
141 statements · 4 reference databases · Subject: AK2 · Sources: Bgee, Hetionet, Human-GEM, Reactome
4 reactions
6 names
Resolves to: AK2
Reaction pageReversibleBalancedEC 2.7.4.3mitochondrial matrix
Human-GEM MAR04004CC BY 4.0Reference data
ADP+CHEBI:16174ATP+MAM01639c
Catalysed by AK2 or AK6 or AK1 or AK7 or AK3 or AK5 or AK9 or AK4 or AK8 or ACAD9
Reaction pageReversibleBalancedEC 2.7.4.11, 2.7.4.3cytosol
Human-GEM MAR04480CC BY 4.0Reference data