1-octadecanoyl-sn-glycero-3-phosphate

Three steps

• CHEBI:15380Reach from here →
  1. 1-acylglycerol-3P-LD-TG1 pool (liver tissue) formation
  2. acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase
  3. 5-aminolevulinate synthase (2-amino-3-oxoadipate)

  Catalysed by AGPAT2, LCLAT1, MBOAT1, MBOAT2 and 7 morecytosol, mitochondrial matrixOne of 8 routes

• CHEBI:15477Reach from here →
  1. 1-acylglycerol-3P-LD-TG1 pool (liver tissue) formation
  2. acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase
  3. glycine N-acyltransferase (2-methylbutyryl-CoA)

  Catalysed by AGPAT2, LCLAT1, MBOAT1, MBOAT2 and 8 morecytosol, mitochondrial matrixOne of 2 routes

• 2-methylcrotonoyl-CoAReach from here →
  1. 1-acylglycerol-3P-LD-TG1 pool (liver tissue) formation
  2. acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase
  3. Production of Tiglylcarnitine

  Catalysed by AGPAT2, LCLAT1, MBOAT1, MBOAT2 and 7 morecytosol, mitochondrial matrixOne of 2 routes

• isobutyryl-CoAReach from here →
  1. 1-acylglycerol-3P-LD-TG1 pool (liver tissue) formation
  2. acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase
  3. acetyl-CoA C-acyltransferase (3-oxo-4-methyl-pentanoyl-CoA)

  Catalysed by AGPAT2, LCLAT1, MBOAT1, MBOAT2 and 8 morecytosol, mitochondrial matrixOne of 3 routes

• 3-methylbut-2-enoyl-CoAReach from here →
  1. 1-acylglycerol-3P-LD-TG1 pool (liver tissue) formation
  2. acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase
  3. glycine-N-acyltransferase (3-methylcrotonoylglycine)

  Catalysed by AGPAT2, LCLAT1, MBOAT1, MBOAT2 and 6 morecytosol, mitochondrial matrix

• isovaleryl-CoAReach from here →
  1. 1-acylglycerol-3P-LD-TG1 pool (liver tissue) formation
  2. acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase
  3. glycine N-acyltransferase (isovalerylglycine)

  Catalysed by AGPAT2, LCLAT1, MBOAT1, MBOAT2 and 8 morecytosol, mitochondrial matrixOne of 3 routes

• arachidonoyl-CoAReach from here →
  1. 1-acylglycerol-3P-LD-TG1 pool (liver tissue) formation
  2. acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase
  3. Arachidonate:CoA ligase (AMP-forming)

  Catalysed by AGPAT2, LCLAT1, MBOAT1, MBOAT2 and 13 morecytosol, mitochondrial matrixOne of 14 routes

• CHEBI:15519Reach from here →
  1. 1-acylglycerol-3P-LD-TG1 pool (liver tissue) formation
  2. acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase
  3. propanoyl-CoA C-acyltransferase

  Catalysed by AGPAT2, LCLAT1, MBOAT1, MBOAT2 and 8 morecytosol, mitochondrial matrix, peroxisomeOne of 2 routes

• palmitoyl-CoAReach from here →
  1. 1-acylglycerol-3P-LD-TG1 pool (liver tissue) formation
  2. acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase
  3. Palmitate:CoA ligase (AMP-forming)

  Catalysed by AGPAT2, LCLAT1, MBOAT1, MBOAT2 and 13 morecytosol, mitochondrial matrixOne of 11 routes

• oleoyl-CoAReach from here →
  1. 1-acylglycerol-3P-LD-TG1 pool (liver tissue) formation
  2. acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase
  3. Transport of octadecenoyl-CoA into Mitochondrial Matrix

  Catalysed by AGPAT2, LCLAT1, MBOAT1, MBOAT2 and 8 morecytosol, mitochondrial matrixOne of 11 routes

• phenylacetyl-CoAReach from here →
  1. 1-acylglycerol-3P-LD-TG1 pool (liver tissue) formation
  2. acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase
  3. Phenylacetate:CoA ligase

  Catalysed by AGPAT2, LCLAT1, MBOAT1, MBOAT2 and 5 morecytosol, mitochondrial matrixOne of 3 routes

• propionyl-CoAReach from here →
  1. 1-acylglycerol-3P-LD-TG1 pool (liver tissue) formation
  2. acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase
  3. Propanoate:CoA ligase (AMP-forming)

  Catalysed by AGPAT2, LCLAT1, MBOAT1, MBOAT2 and 8 morecytosol, mitochondrial matrixOne of 43 routes

• 12(S)-HPETEReach from here →
  1. 1-octadecanoyl-sn-glycero-3-phosphate + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + CoA
  2. 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + H2O = 1-octadecanoyl-sn-glycero-3-phosphate + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)
  3. arachidonate:oxygen 12-oxidoreductase

  Catalysed by AGPAT3, PLA2G4A, ALOX12cytosolOne of 4 routes

• 15(S)-HPETEReach from here →
  1. 1-octadecanoyl-sn-glycero-3-phosphate + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + CoA
  2. 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + H2O = 1-octadecanoyl-sn-glycero-3-phosphate + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)
  3. arachidonate:oxygen 15-oxidoreductase

  Catalysed by AGPAT3, PLA2G4A, ALOX15B, ALOX15cytosolOne of 4 routes

• 5(S)-HPETEReach from here →
  1. 1-octadecanoyl-sn-glycero-3-phosphate + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + CoA
  2. 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + H2O = 1-octadecanoyl-sn-glycero-3-phosphate + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)
  3. Arachidonate:oxygen 5-oxidoreductase

  Catalysed by AGPAT3, PLA2G4A, ALOX5cytosol

• CHEBI:15650Reach from here →
  1. 1-acylglycerol-3P-LD-TG1 pool (liver tissue) formation
  2. acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase
  3. N-acetyl-LTE4 to leukotriene E4 conversion

  Catalysed by AGPAT2, LCLAT1, MBOAT1, MBOAT2 and 36 morecytosol, mitochondrial matrixOne of 2 routes

• CHEBI:15727Reach from here →
  1. 1-acylglycerol-3P-LD-TG1 pool (liver tissue) formation
  2. acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase
  3. N-alpha-acetyltransferase 10, NatA catalytic subunit (acetylcarnosine)

  Catalysed by AGPAT2, LCLAT1, MBOAT1, MBOAT2 and 6 morecytosol, mitochondrial matrix

• CHEBI:15746Reach from here →
  1. 1-acylglycerol-3P-LD-TG1 pool (liver tissue) formation
  2. acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase
  3. diamine N-acetyltransferase (N1-acetylspermine)

  Catalysed by AGPAT2, LCLAT1, MBOAT1, MBOAT2 and 7 morecytosol, mitochondrial matrixOne of 2 routes

• 11-cis-retinolReach from here →
  1. 1-acylglycerol-3P-LD-TG1 pool (liver tissue) formation
  2. acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase
  3. Palmitoyl-CoA:retinol O-acyltransferase

  Catalysed by AGPAT2, LCLAT1, MBOAT1, MBOAT2 and 10 morecytosol, mitochondrial matrix

• oxaloacetateReach from here →
  1. 1-acylglycerol-3P-LD-TG1 pool (liver tissue) formation
  2. acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase
  3. ATP citrate lyase (citrate)

  Catalysed by AGPAT2, LCLAT1, MBOAT1, MBOAT2 and 6 morecytosol, mitochondrial matrix

• CHEBI:16856Reach from here →
  1. 1-octadecanoyl-sn-glycero-3-phosphate + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + CoA
  2. 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + H2O = 1-octadecanoyl-sn-glycero-3-phosphate + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)
  3. transport of arachidonate and GSH (cytosol to extracellular)

  Catalysed by AGPAT3, PLA2G4Aextracellular space, cytosolOne of 2 routes

• octadecanalReach from here →
  1. 1-octadecanoyl-sn-glycero-3-phosphate + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + CoA
  2. 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + H2O = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + octadecanoate + H(+)
  3. octadecanal + NAD(+) + H2O = octadecanoate + NADH + 2 H(+)

  Catalysed by AGPAT3, DDHD1, ALDH3A2

• anilineReach from here →
  1. 1-acylglycerol-3P-LD-TG1 pool (liver tissue) formation
  2. acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase
  3. Acetyl-CoA:arylamine N-acetyltransferase

  Catalysed by AGPAT2, LCLAT1, MBOAT1, MBOAT2 and 7 morecytosol, mitochondrial matrix

• CHEBI:17312Reach from here →
  1. 1-acylglycerol-3P-LD-TG1 pool (liver tissue) formation
  2. acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase
  3. N1,N12-diacetylspermine to N1-acetylspermine conversion

  Catalysed by AGPAT2, LCLAT1, MBOAT1, MBOAT2 and 5 morecytosol, mitochondrial matrixOne of 2 routes

• L-cysteineReach from here →
  1. 1-acylglycerol-3P-LD-TG1 pool (liver tissue) formation
  2. acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase
  3. N-acetylglutamate synthase (N-acetyl-L-cysteine)

  Catalysed by AGPAT2, LCLAT1, MBOAT1, MBOAT2 and 6 morecytosol, mitochondrial matrix

• (7Z,10Z,13Z)-hexadecatrienoyl-CoAReach from here →
  1. 1-acylglycerol-3P-LD-TG1 pool (liver tissue) formation
  2. acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase
  3. Fatty Acid Beta Oxidation (C18:3->C16:3), Mitochondrial

  Catalysed by AGPAT2, LCLAT1, MBOAT1, MBOAT2 and 8 morecytosol, mitochondrial matrix

• a 1,2-diacyl-sn-glycerolReach from here →
  1. 1-acylglycerol-3P-LD-TG1 pool (liver tissue) formation
  2. acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase
  3. Diacylglycerol Phosphate Kinase (Homo Sapiens)

  Catalysed by AGPAT2, LCLAT1, MBOAT1, MBOAT2 and 7 morecytosol, mitochondrial matrix, nucleusOne of 8 routes

• CHEBI:17927Reach from here →
  1. 1-acylglycerol-3P-LD-TG1 pool (liver tissue) formation
  2. acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase
  3. N1,N8-diacetylspermidine to N1-acetylspermidine conversion

  Catalysed by AGPAT2, LCLAT1, MBOAT1, MBOAT2 and 5 morecytosol, mitochondrial matrix

• 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-glycerolReach from here →
  1. 1-octadecanoyl-sn-glycero-3-phosphate + (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + CoA
  2. 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + H2O = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycerol + phosphate
  3. 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycerol + H2O = 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-glycerol + octadecanoate + H(+)

  Catalysed by AGPAT4, LPIN1, ABHD11

• (5Z)-dodecenoyl-CoAReach from here →
  1. 1-acylglycerol-3P-LD-TG1 pool (liver tissue) formation
  2. acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase
  3. acetyl-CoA C-acyltransferase (3-oxomyrist-7-enoyl-CoA)

  Catalysed by AGPAT2, LCLAT1, MBOAT1, MBOAT2 and 8 morecytosol, mitochondrial matrixOne of 2 routes

• O-[(5Z),(8Z),(11Z),(14Z)-eicosatetraenoyl]-beta-D-glucuronateReach from here →
  1. 1-octadecanoyl-sn-glycero-3-phosphate + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + CoA
  2. 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + H2O = 1-octadecanoyl-sn-glycero-3-phosphate + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)
  3. (5Z,8Z,11Z,14Z)-eicosatetraenoate + UDP-alpha-D-glucuronate = O-[(5Z),(8Z),(11Z),(14Z)-eicosatetraenoyl]-beta-D-glucuronate + UDP

  Catalysed by AGPAT3, PLA2G4A, UGT1A9, UGT2B7 and 4 more

• (11Z)-docosenoyl-CoA(4-)Reach from here →
  1. 1-acylglycerol-3P-LD-TG1 pool (liver tissue) formation
  2. acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase
  3. long-chain-fatty-acid-CoA ligase (cis-cetoleic acid)

  Catalysed by AGPAT2, LCLAT1, MBOAT1, MBOAT2 and 13 morecytosol, mitochondrial matrixOne of 5 routes

• (7Z)-tetradecenoyl-CoAReach from here →
  1. 1-acylglycerol-3P-LD-TG1 pool (liver tissue) formation
  2. acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase
  3. long-chain-fatty-acid-CoA ligase ((7Z)-tetradecenoic acid)

  Catalysed by AGPAT2, LCLAT1, MBOAT1, MBOAT2 and 13 morecytosol, mitochondrial matrixOne of 8 routes

• (4Z,7Z,10Z,13Z)-hexadecatetraenoyl-CoAReach from here →
  1. 1-acylglycerol-3P-LD-TG1 pool (liver tissue) formation
  2. acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase
  3. Fatty Acid Beta Oxidation (C18:4->C16:4), Mitochondrial

  Catalysed by AGPAT2, LCLAT1, MBOAT1, MBOAT2 and 8 morecytosol, mitochondrial matrixOne of 3 routes

• (7Z,10Z)-hexadecadienoyl-CoAReach from here →
  1. 1-acylglycerol-3P-LD-TG1 pool (liver tissue) formation
  2. acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase
  3. Fatty Acid Beta Oxidation Trans (C18:2->C16:2), Mitochondrial

  Catalysed by AGPAT2, LCLAT1, MBOAT1, MBOAT2 and 8 morecytosol, mitochondrial matrix

• (4Z,7Z)-decadienoyl-CoAReach from here →
  1. 1-acylglycerol-3P-LD-TG1 pool (liver tissue) formation
  2. acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase
  3. Fatty Acid Beta Oxidation (C12:3->C10:2), Mitochondrial

  Catalysed by AGPAT2, LCLAT1, MBOAT1, MBOAT2 and 8 morecytosol, mitochondrial matrixOne of 2 routes

• (5Z)-octenoyl-CoAReach from here →
  1. 1-acylglycerol-3P-LD-TG1 pool (liver tissue) formation
  2. acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase
  3. Fatty Acid Beta Oxidation (C10:2->C8:1), Mitochondrial

  Catalysed by AGPAT2, LCLAT1, MBOAT1, MBOAT2 and 8 morecytosol, mitochondrial matrixOne of 2 routes

• N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamineReach from here →
  1. 1-octadecanoyl-sn-glycero-3-phosphate + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + CoA
  2. 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + H2O = 1-octadecanoyl-sn-glycero-3-phosphate + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)
  3. fatty acylamide amidohydrolase

  Catalysed by AGPAT3, PLA2G4A, FAAHcytosol

• CHEBI:27540Reach from here →
  1. 1-acylglycerol-3P-LD-TG1 pool (liver tissue) formation
  2. acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase
  3. medium-chain acyl-CoA ligase (hexanoic acid)

  Catalysed by AGPAT2, LCLAT1, MBOAT1, MBOAT2 and 11 morecytosol, mitochondrial matrixOne of 6 routes

• elaidic acidReach from here →
  1. 1-acylglycerol-3P-LD-TG1 pool (liver tissue) formation
  2. acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase
  3. long-chain-fatty-acid-CoA ligase (elaidate)

  Catalysed by AGPAT2, LCLAT1, MBOAT1, MBOAT2 and 13 morecytosol, mitochondrial matrixOne of 5 routes

• CHEBI:28701Reach from here →
  1. 1-acylglycerol-3P-LD-TG1 pool (liver tissue) formation
  2. acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase
  3. Propanoyl-CoA:acetyl-CoA C-acyltransferase

  Catalysed by AGPAT2, LCLAT1, MBOAT1, MBOAT2 and 8 morecytosol, mitochondrial matrix, peroxisomeOne of 7 routes

• (9Z,12Z)-octadecadienoateReach from here →
  1. 1-octadecanoyl-sn-glycero-3-phosphate + (9Z,12Z)-octadecadienoyl-CoA = 1-octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + CoA
  2. 1-octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + H2O = 1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycerol + phosphate
  3. 1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycerol + H2O = 1-octadecanoyl-sn-glycerol + (9Z,12Z)-octadecadienoate + H(+)

  Catalysed by AGPAT4, LPIN1, PLB1

• 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerolReach from here →
  1. 1-acylglycerol-3P-LD-TG1 pool (liver tissue) formation
  2. 1-acylglycerol-3-phosphate pool formation and breakdown
  3. 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + H2O = 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + phosphate

  Catalysed by EPHX2cytosol

• fatty acidReach from here →
  1. 1-acylglycerol-3P-LD-TG1 pool (liver tissue) formation
  2. aldo-keto reductase (1-acylglycerol-3P pool)
  3. alkylglycerone phosphate synthase (acylglycerone-phosphate)

  Catalysed by AKR1A1, AGPScytosol, peroxisomeOne of 9 routes

• taurineReach from here →
  1. 1-acylglycerol-3P-LD-TG1 pool (liver tissue) formation
  2. acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase
  3. bile acid-CoA:amino acid N-acyltransferase (taurodeoxycholate)

  Catalysed by AGPAT2, LCLAT1, MBOAT1, MBOAT2 and 6 morecytosol, mitochondrial matrixOne of 2 routes

• 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerolReach from here →
  1. 1-octadecanoyl-sn-glycero-3-phosphate + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + CoA
  2. 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + H2O = 1-octadecanoyl-sn-glycero-3-phosphate + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)
  3. fatty acid amide hydrolase (2-arachidonoylglycerol)

  Catalysed by AGPAT3, PLA2G4A, FAAHcytosolOne of 5 routes

• glycineReach from here →
  1. 1-acylglycerol-3P-LD-TG1 pool (liver tissue) formation
  2. acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase
  3. glycine N-acyltransferase (N-arachidonoylglycine)

  Catalysed by AGPAT2, LCLAT1, MBOAT1, MBOAT2 and 8 morecytosol, mitochondrial matrixOne of 10 routes

• (R)-methylmalonyl-CoAReach from here →
  1. 1-acylglycerol-3P-LD-TG1 pool (liver tissue) formation
  2. acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase
  3. aldehyde dehydrogenase (2-methyl-3-oxopropanoate)

  Catalysed by AGPAT2, LCLAT1, MBOAT1, MBOAT2 and 6 morecytosol, mitochondrial matrixOne of 2 routes

• (S)-methylmalonyl-CoAReach from here →
  1. 1-acylglycerol-3P-LD-TG1 pool (liver tissue) formation
  2. acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase
  3. (S)-methylmalonyl-CoA hydrolase

  Catalysed by AGPAT2, LCLAT1, MBOAT1, MBOAT2 and 5 morecytosol, mitochondrial matrix

• 3'-dephospho-CoAReach from here →
  1. 1-acylglycerol-3P-LD-TG1 pool (liver tissue) formation
  2. acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase
  3. acid phosphatase 2, lysosomal (CoA)

  Catalysed by AGPAT2, LCLAT1, MBOAT1, MBOAT2 and 6 morecytosol, mitochondrial matrix, lysosomeOne of 2 routes