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Proteins/UNIPROT:P51648
Catalyzes the oxidation of medium and long chain aliphatic aldehydes to fatty acids. Active on a variety of saturated and unsaturated aliphatic aldehydes between 6 and 24 carbons in length. Responsible for conversion of the sphingosine 1-phosphate (S1P) degradation product hexadecenal to hexadecenoic acid..
Function from UniProtKB (P51648), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
172 statements
172 statements · 7 reference databases · Subject: ALDH3A2 · Sources: Bgee, Hetionet, Human Protein Atlas, Human-GEM, Reactome, Rhea, WikiPathways
63 reactions
2,6,10,14-tetramethylpentadecanal+water+NAD(+)2proton+NADH(2-)+2,6,10,14-tetramethylpentadecanoate
Catalysed by ALDH3A2
Reaction pageLeft to rightBalancedEC 1.2.1.-cytosol
Human-GEM MAR00067CC BY 4.0Reference data
MAM01981c+water+NAD(+)(R)-glycerate+2proton
5 names
Resolves to: ALDH3A2
Reaction pageLeft to rightBalancedEC 1.2.1.3cytosol
Human-GEM MAR00456CC BY 4.0Reference data
MAM01981m+water+NAD(+)(R)-glycerate+2proton+NADH(2-)
Catalysed by ALDH3A2 or ALDH2 or ALDH1B1 or ALDH9A1 or ALDH7A1
Reaction pageLeft to rightBalancedEC 1.2.1.3mitochondrial matrix
Human-GEM MAR00459CC BY 4.0Reference data
MAM00585c+2proton+NADH(2-)MAM00600c+water+NAD(+)
Catalysed by ALDH3A2 or ALDH2 or ALDH1B1 or ALDH9A1 or ALDH7A1
Reaction pageReversibleBalancedEC 1.2.1.3cytosol
Human-GEM MAR01132CC BY 4.0Reference data
MAM00585m+2proton+NADH(2-)MAM00600m+water+NAD(+)
Catalysed by ALDH3A2 or ALDH2 or ALDH1B1 or ALDH9A1 or ALDH7A1
Reaction pageReversibleBalancedEC 1.2.1.3mitochondrial matrix
Human-GEM MAR01133CC BY 4.0Reference data
MAM00585r+2proton+NADH(2-)MAM00600r+water+NAD(+)
Catalysed by ALDH3A2 or ALDH2 or ALDH1B1 or ALDH9A1 or ALDH7A1
Reaction pageReversibleBalancedEC 1.2.1.3endoplasmic reticulum
Human-GEM MAR01134CC BY 4.0Reference data
MAM00601x+water+NAD(+)MAM00586x+2proton+NADH(2-)
Catalysed by ALDH3A2 or ALDH2 or ALDH1B1 or ALDH9A1 or ALDH7A1
Reaction pageLeft to rightBalancedEC 1.2.1.3peroxisome
Human-GEM MAR01289CC BY 4.0Reference data
MAM00756c+water+NAD(+)MAM00758c+2proton+NADH(2-)
Catalysed by ALDH3A2 or ALDH2 or ALDH1B1 or ALDH9A1 or ALDH7A1
Reaction pageReversibleBalancedEC 1.2.1.3cytosol
Human-GEM MAR01692CC BY 4.0Reference data
2,6,10,14-tetramethylpentadecanal+water+NAD(+)2proton+NADH(2-)+2,6,10,14-tetramethylpentadecanoate
Catalysed by ALDH3A2
Reaction pageReversibleBalancedEC 1.2.1.48peroxisome
Human-GEM MAR03386CC BY 4.0Reference data
2-methyl-3-oxopropanoic acid+water+NAD(+)2proton+MAM02479m+NADH(2-)
Catalysed by ALDH3A2 or ALDH2 or ALDH1B1 or AOX1 or ALDH9A1 or ALDH7A1
Reaction pageLeft to rightBalancedEC 1.2.1.3, 1.2.3.1mitochondrial matrix
Human-GEM MAR03759CC BY 4.0Reference data
(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate+2proton+NADH(2-)(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al+water+NAD(+)
Catalysed by ALDH3A2 or ALDH3A1
Reaction pageReversibleBalancedEC 1.2.1.3endoplasmic reticulum
Human-GEM MAR03821CC BY 4.0Reference data
3-aminopropanal+water+NADP(3-)beta-alanine+2proton+NADPH(4-)
Catalysed by ALDH3A2 or ALDH2 or ALDH1B1 or ALDH9A1 or ALDH7A1
Reaction pageLeft to rightBalancedEC 1.2.1.3cytosol
Human-GEM MAR04079CC BY 4.0Reference data