1-octadecanoyl-sn-glycero-3-phosphate

1. 1-acylglycerol-3P-LD-TG1 pool (liver tissue) formation

No catalyst recordedcytosolOne of 8 routes

1. 1-octadecanoyl-sn-glycero-3-phosphate + (9Z)-octadecenoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA

Catalysed by LPCAT2, ABHD5, AGPAT3, AGPAT5

1. 1-octadecanoyl-sn-glycero-3-phosphate + H2O = 1-octadecanoyl-sn-glycerol + phosphate

Catalysed by EPHX2

1. 1-octadecanoyl-sn-glycero-3-phosphate + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + CoA

Catalysed by AGPAT3

1. 1-octadecanoyl-sn-glycero-3-phosphate + (9Z,12Z)-octadecadienoyl-CoA = 1-octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + CoA

Catalysed by AGPAT4

1. 1-octadecanoyl-sn-glycero-3-phosphate + (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + CoA

Catalysed by AGPAT4

1. 1-acylglycerol-3P-LD-TG1 pool (liver tissue) formation
2. acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase

Catalysed by AGPAT2, LCLAT1, MBOAT1, MBOAT2 and 5 morecytosol, mitochondrial matrixOne of 8 routes

1. 1-acylglycerol-3P-LD-TG1 pool (liver tissue) formation
2. aldo-keto reductase (1-acylglycerol-3P pool)

Catalysed by AKR1A1cytosol

1. 1-acylglycerol-3P-LD-TG1 pool (liver tissue) formation
2. acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase
3. Carnitine O-Palmitoyltransferase

Catalysed by AGPAT2, LCLAT1, MBOAT1, MBOAT2 and 8 morecytosol, mitochondrial matrixOne of 246 routes

1. 1-octadecanoyl-sn-glycero-3-phosphate + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + CoA
2. 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + H2O = 1-octadecanoyl-sn-glycero-3-phosphate + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)
3. (5Z,8Z,11Z,14Z)-eicosatetraenoate + AH2 + 2 O2 = prostaglandin H2 + A + H2O