oxalate

Three steps

• methanethiolReach from here →
  1. oxalate(in) + formate(out) = oxalate(out) + formate(in)
  2. formaldehyde + NAD(+) + H2O = formate + NADH + 2 H(+)
  3. methanethiol + O2 + H2O = hydrogen sulfide + formaldehyde + H2O2 + H(+)

  Catalysed by SLC26A6, ALDH9A1, SELENBP1inner side of the membrane, outer side of the membrane

• androsteroneReach from here →
  1. oxalate(in) + sulfate(out) = oxalate(out) + sulfate(in)
  2. steroid sulfatase (androsterone sulfate)
  3. steroid sulfatase (androsterone sulfate)

  Catalysed by SLC25A14, SLC26A2, SLC25A30, SLC26A6 and 2 moreinner side of the membrane, outer side of the membrane, cytosolOne of 3 routes

• L-cystineReach from here →
  1. oxalate(in) + sulfate(out) = oxalate(out) + sulfate(in)
  2. L-aspartate(in) + sulfate(out) = L-aspartate(out) + sulfate(in)
  3. L-cystine(out) + L-aspartate(in) = L-cystine(in) + L-aspartate(out)

  Catalysed by SLC25A14, SLC26A2, SLC25A30, SLC26A6 and 2 moreinner side of the membrane, outer side of the membraneOne of 2 routes

• 17beta-hydroxy-5alpha-androstan-3-oneReach from here →
  1. oxalate(in) + sulfate(out) = oxalate(out) + sulfate(in)
  2. steroid sulfatase (5-alpha-dihydrotestosterone)
  3. steroid sulfatase (5-alpha-dihydrotestosterone)

  Catalysed by SLC25A14, SLC26A2, SLC25A30, SLC26A6 and 2 moreinner side of the membrane, outer side of the membrane, cytosolOne of 3 routes

• iodideReach from here →
  1. oxalate(in) + sulfate(out) = oxalate(out) + sulfate(in)
  2. transport of chloride and sulfate (cytosol to extracellular)
  3. transport of chloride and iodide (cytosol to extracellular)

  Catalysed by SLC25A14, SLC26A2, SLC25A30, SLC26A6 and 2 moreinner side of the membrane, outer side of the membrane, extracellular space, cytosol

• ubiquinonesReach from here →
  1. oxalate(in) + sulfate(out) = oxalate(out) + sulfate(in)
  2. transport of fumarate and sulfate (cytosol to mitochondria)
  3. succinate:quinone oxidoreductase

  Catalysed by SLC25A14, SLC26A2, SLC25A30, SLC26A6 and 6 moreinner side of the membrane, outer side of the membrane, mitochondrial matrix, cytosol

• L-valineReach from here →
  1. oxalate(in) + sulfate(out) = oxalate(out) + sulfate(in)
  2. transport of chloride and sulfate (cytosol to extracellular)
  3. transport of chloride and valine (cytosol to extracellular)

  Catalysed by SLC25A14, SLC26A2, SLC25A30, SLC26A6 and 2 moreinner side of the membrane, outer side of the membrane, extracellular space, cytosolOne of 4 routes

• oxaloacetateReach from here →
  1. oxalate(in) + sulfate(out) = oxalate(out) + sulfate(in)
  2. transport of malate and sulfate (cytosol to mitochondria)
  3. transport of malate and OAA (cytosol to mitochondria)

  Catalysed by SLC25A14, SLC26A2, SLC25A30, SLC26A6 and 2 moreinner side of the membrane, outer side of the membrane, mitochondrial matrix, cytosolOne of 11 routes

• L-arginineReach from here →
  1. oxalate(in) + sulfate(out) = oxalate(out) + sulfate(in)
  2. transport of chloride and sulfate (cytosol to extracellular)
  3. transport of arginine and chloride (cytosol to extracellular)

  Catalysed by SLC25A14, SLC26A2, SLC25A30, SLC26A6 and 2 moreinner side of the membrane, outer side of the membrane, extracellular space, cytosolOne of 2 routes

• protein polypeptide chainReach from here →
  1. oxalate(in) + sulfate(out) = oxalate(out) + sulfate(in)
  2. L-aspartate(in) + sulfate(out) = L-aspartate(out) + sulfate(in)
  3. PROTEIN_BS

  Catalysed by SLC25A14, SLC26A2, SLC25A30, SLC26A6 and 1 moreinner side of the membrane, outer side of the membrane, cytosol

• pregnenoloneReach from here →
  1. oxalate(in) + sulfate(out) = oxalate(out) + sulfate(in)
  2. Steryl-Sulfatase
  3. Pregnenolone-sulfate sulfohydrolase

  Catalysed by SLC25A14, SLC26A2, SLC25A30, SLC26A6 and 2 moreinner side of the membrane, outer side of the membrane, Golgi apparatus, cytosolOne of 4 routes

• 4-methylsulfanyl-2-oxobutanoateReach from here →
  1. oxalate(in) + formate(out) = oxalate(out) + formate(in)
  2. 1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + O2 = 3-(methylsulfanyl)propanoate + CO + formate + 2 H(+)
  3. 1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + O2 = 4-methylsulfanyl-2-oxobutanoate + formate + 2 H(+)

  Catalysed by SLC26A6, ADI1inner side of the membrane, outer side of the membrane

• 3-fumarylpyruvateReach from here →
  1. oxalate(in) + sulfate(out) = oxalate(out) + sulfate(in)
  2. transport of fumarate and sulfate (cytosol to mitochondria)
  3. 3-fumarylpyruvate + H2O = fumarate + pyruvate + H(+)

  Catalysed by SLC25A14, SLC26A2, SLC25A30, SLC26A6 and 3 moreinner side of the membrane, outer side of the membrane, mitochondrial matrix, cytosol

• CHEBI:16856Reach from here →
  1. oxalate(in) + formate(out) = oxalate(out) + formate(in)
  2. S-formylglutathione + H2O = formate + glutathione + H(+)
  3. S-Formylglutathione hydrolase

  Catalysed by SLC26A6, ESDinner side of the membrane, outer side of the membrane, cytosolOne of 2 routes

• CHEBI:16857Reach from here →
  1. oxalate(in) + sulfate(out) = oxalate(out) + sulfate(in)
  2. transport of chloride and sulfate (cytosol to extracellular)
  3. Transport of L-Threonine by Atb0 Transporter

  Catalysed by SLC25A14, SLC26A2, SLC25A30, SLC26A6 and 2 moreinner side of the membrane, outer side of the membrane, extracellular space, cytosol

• ferrocytochrome cReach from here →
  1. oxalate(in) + sulfate(out) = oxalate(out) + sulfate(in)
  2. sulfite(in) + sulfate(out) = sulfite(out) + sulfate(in)
  3. sulfite:ferricytochrome-c oxidoreductase

  Catalysed by SLC25A14, SLC26A2, SLC25A30, SLC26A6 and 2 moreinner side of the membrane, outer side of the membrane, mitochondrial matrix, cytosol

• N-acetyl-L-aspartateReach from here →
  1. oxalate(in) + sulfate(out) = oxalate(out) + sulfate(in)
  2. L-aspartate(in) + sulfate(out) = L-aspartate(out) + sulfate(in)
  3. acetyl-CoA:L-aspartate N-acetyltransferase

  Catalysed by SLC25A14, SLC26A2, SLC25A30, SLC26A6 and 2 moreinner side of the membrane, outer side of the membrane, mitochondrial matrixOne of 2 routes

• L-isoleucineReach from here →
  1. oxalate(in) + sulfate(out) = oxalate(out) + sulfate(in)
  2. transport of chloride and sulfate (cytosol to extracellular)
  3. transport of chloride and isoleucine (cytosol to extracellular)

  Catalysed by SLC25A14, SLC26A2, SLC25A30, SLC26A6 and 2 moreinner side of the membrane, outer side of the membrane, extracellular space, cytosolOne of 2 routes

• CHEBI:17203Reach from here →
  1. oxalate(in) + sulfate(out) = oxalate(out) + sulfate(in)
  2. transport of chloride and sulfate (cytosol to extracellular)
  3. Transport of L-Proline by the Apical Imino Amino Acid Transporters

  Catalysed by SLC25A14, SLC26A2, SLC25A30, SLC26A6 and 3 moreinner side of the membrane, outer side of the membrane, extracellular space, cytosolOne of 3 routes

• COReach from here →
  1. oxalate(in) + formate(out) = oxalate(out) + formate(in)
  2. 1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + O2 = 3-(methylsulfanyl)propanoate + CO + formate + 2 H(+)
  3. acireductone dioxygenase

  Catalysed by SLC26A6, ADI1inner side of the membrane, outer side of the membrane, cytosolOne of 2 routes

• estroneReach from here →
  1. oxalate(in) + sulfate(out) = oxalate(out) + sulfate(in)
  2. estrone 3-sulfate + H2O = estrone + sulfate + H(+)
  3. Estrone 3-sulfate sulfohydrolase

  Catalysed by SLC25A14, SLC26A2, SLC25A30, SLC26A6 and 2 moreinner side of the membrane, outer side of the membrane, cytosolOne of 3 routes

• propanoateReach from here →
  1. oxalate(in) + sulfate(out) = oxalate(out) + sulfate(in)
  2. dehydroepiandrosterone 3-sulfate + H2O = 3beta-hydroxyandrost-5-en-17-one + sulfate + H(+)
  3. propanoate(out) + dehydroepiandrosterone 3-sulfate(in) = propanoate(in) + dehydroepiandrosterone 3-sulfate(out)

  Catalysed by SLC25A14, SLC26A2, SLC25A30, SLC26A6 and 3 moreinner side of the membrane, outer side of the membraneOne of 4 routes

• enol-oxaloacetateReach from here →
  1. oxalate(in) + sulfate(out) = oxalate(out) + sulfate(in)
  2. transport of malate and sulfate (cytosol to mitochondria)
  3. (S)-malate + a quinone = enol-oxaloacetate + a quinol

  Catalysed by SLC25A14, SLC26A2, SLC25A30, SLC26A6 and 4 moreinner side of the membrane, outer side of the membrane, mitochondrial matrix, cytosol

• L-cysteineReach from here →
  1. oxalate(in) + sulfate(out) = oxalate(out) + sulfate(in)
  2. transport of chloride and sulfate (cytosol to extracellular)
  3. transport of chloride and cysteine (cytosol to extracellular)

  Catalysed by SLC25A14, SLC26A2, SLC25A30, SLC26A6 and 2 moreinner side of the membrane, outer side of the membrane, extracellular space, cytosolOne of 2 routes

• 3,3'-diiodo-L-thyronineReach from here →
  1. oxalate(in) + sulfate(out) = oxalate(out) + sulfate(in)
  2. Steryl-Sulfatase
  3. Steryl-Sulfatase

  Catalysed by SLC25A14, SLC26A2, SLC25A30, SLC26A6 and 2 moreinner side of the membrane, outer side of the membrane, Golgi apparatusOne of 3 routes

• CHEBI:17724Reach from here →
  1. oxalate(in) + formate(out) = oxalate(out) + formate(in)
  2. formaldehyde + NAD(+) + H2O = formate + NADH + 2 H(+)
  3. dimethylglycine dehydrogenase (formaldehyde)

  Catalysed by SLC26A6, ALDH9A1, PDPR, DMGDHinner side of the membrane, outer side of the membrane, cytosol

• glycine betaineReach from here →
  1. oxalate(in) + sulfate(out) = oxalate(out) + sulfate(in)
  2. transport of chloride and sulfate (cytosol to extracellular)
  3. transport of betaine and chloride (cytosol to extracellular)

  Catalysed by SLC25A14, SLC26A2, SLC25A30, SLC26A6 and 2 moreinner side of the membrane, outer side of the membrane, extracellular space, cytosolOne of 3 routes

• urateReach from here →
  1. oxalate(in) + sulfate(out) = oxalate(out) + sulfate(in)
  2. a dicarboxylate(in) + sulfate(out) = a dicarboxylate(out) + sulfate(in)
  3. urate(out) + a dicarboxylate(in) = urate(in) + a dicarboxylate(out)

  Catalysed by SLC25A14, SLC26A2, SLC25A30, SLC26A6 and 4 moreinner side of the membrane, outer side of the membraneOne of 2 routes

• CHEBI:17895Reach from here →
  1. oxalate(in) + sulfate(out) = oxalate(out) + sulfate(in)
  2. transport of chloride and sulfate (cytosol to extracellular)
  3. Transport of L-Tyrosine by Atb0 Transporter

  Catalysed by SLC25A14, SLC26A2, SLC25A30, SLC26A6 and 2 moreinner side of the membrane, outer side of the membrane, extracellular space, cytosolOne of 2 routes

• butanoateReach from here →
  1. oxalate(in) + sulfate(out) = oxalate(out) + sulfate(in)
  2. dehydroepiandrosterone 3-sulfate + H2O = 3beta-hydroxyandrost-5-en-17-one + sulfate + H(+)
  3. dehydroepiandrosterone 3-sulfate(in) + butanoate(out) = dehydroepiandrosterone 3-sulfate(out) + butanoate(in)

  Catalysed by SLC25A14, SLC26A2, SLC25A30, SLC26A6 and 3 moreinner side of the membrane, outer side of the membraneOne of 4 routes

• CHEBI:18019Reach from here →
  1. oxalate(in) + sulfate(out) = oxalate(out) + sulfate(in)
  2. transport of chloride and sulfate (cytosol to extracellular)
  3. transport of chloride and lysine (cytosol to extracellular)

  Catalysed by SLC25A14, SLC26A2, SLC25A30, SLC26A6 and 2 moreinner side of the membrane, outer side of the membrane, extracellular space, cytosol

• thiocyanateReach from here →
  1. oxalate(in) + sulfate(out) = oxalate(out) + sulfate(in)
  2. thiosulfate(in) + sulfate(out) = thiosulfate(out) + sulfate(in)
  3. thiosulfate:cyanide sulfurtranserase

  Catalysed by SLC25A14, SLC26A2, SLC25A30, SLC26A6 and 4 moreinner side of the membrane, outer side of the membrane, mitochondrial matrixOne of 2 routes

• 4-fumarylacetoacetateReach from here →
  1. oxalate(in) + sulfate(out) = oxalate(out) + sulfate(in)
  2. transport of fumarate and sulfate (cytosol to mitochondria)
  3. 4-fumarylacetoacetate + H2O = acetoacetate + fumarate + H(+)

  Catalysed by SLC25A14, SLC26A2, SLC25A30, SLC26A6 and 3 moreinner side of the membrane, outer side of the membrane, mitochondrial matrix, cytosol

• L-glutamineReach from here →
  1. oxalate(in) + sulfate(out) = oxalate(out) + sulfate(in)
  2. transport of chloride and sulfate (cytosol to extracellular)
  3. Transport of L-Glutamine by Atb0 Transporter

  Catalysed by SLC25A14, SLC26A2, SLC25A30, SLC26A6 and 2 moreinner side of the membrane, outer side of the membrane, extracellular space, cytosolOne of 3 routes

• CHEBI:18095Reach from here →
  1. oxalate(in) + sulfate(out) = oxalate(out) + sulfate(in)
  2. transport of chloride and sulfate (cytosol to extracellular)
  3. transport of trans-4-hydroxy-L-proline (cytosol to extracellular)

  Catalysed by SLC25A14, SLC26A2, SLC25A30, SLC26A6 and 3 moreinner side of the membrane, outer side of the membrane, extracellular space, cytosol

• N-carbamoyl-beta-alanineReach from here →
  1. oxalate(in) + sulfate(out) = oxalate(out) + sulfate(in)
  2. transport of chloride and sulfate (cytosol to extracellular)
  3. Transport of 3-Ureidopropionate

  Catalysed by SLC25A14, SLC26A2, SLC25A30, SLC26A6 and 1 moreinner side of the membrane, outer side of the membrane, extracellular space, cytosolOne of 2 routes

• hydrogen cyanideReach from here →
  1. oxalate(in) + sulfate(out) = oxalate(out) + sulfate(in)
  2. sulfite(in) + sulfate(out) = sulfite(out) + sulfate(in)
  3. thiosulfate:cyanide sulfurtranserase

  Catalysed by SLC25A14, SLC26A2, SLC25A30, SLC26A6 and 3 moreinner side of the membrane, outer side of the membrane, mitochondrial matrixOne of 2 routes

• 3-carboxy-4-methyl-5-propyl-2-furanpropanoateReach from here →
  1. oxalate(in) + sulfate(out) = oxalate(out) + sulfate(in)
  2. a dicarboxylate(in) + sulfate(out) = a dicarboxylate(out) + sulfate(in)
  3. 3-carboxy-4-methyl-5-propyl-2-furanpropanoate(out) + a dicarboxylate(in) = 3-carboxy-4-methyl-5-propyl-2-furanpropanoate(in) + a dicarboxylate(out)

  Catalysed by SLC25A14, SLC26A2, SLC25A30, SLC26A6 and 5 moreinner side of the membrane, outer side of the membraneOne of 2 routes

• L-sepiapterinReach from here →
  1. oxalate(in) + sulfate(out) = oxalate(out) + sulfate(in)
  2. a dicarboxylate(in) + sulfate(out) = a dicarboxylate(out) + sulfate(in)
  3. L-sepiapterin(out) + a dicarboxylate(in) = L-sepiapterin(in) + a dicarboxylate(out)

  Catalysed by SLC25A14, SLC26A2, SLC25A30, SLC26A6 and 5 moreinner side of the membrane, outer side of the membraneOne of 2 routes

• (6R)-5,10-methylenetetrahydrofolic acidReach from here →
  1. oxalate(in) + formate(out) = oxalate(out) + formate(in)
  2. formaldehyde + NAD(+) + H2O = formate + NADH + 2 H(+)
  3. formaldehyde to 5,10-methylene-THF conversion

  Catalysed by SLC26A6, ALDH9A1inner side of the membrane, outer side of the membrane, cytosol

• CHEBI:240943Reach from here →
  1. oxalate(in) + sulfate(out) = oxalate(out) + sulfate(in)
  2. transport of chloride and sulfate (cytosol to extracellular)
  3. 2-Methylbutyrylglycine Transport, Extracellular

  Catalysed by SLC25A14, SLC26A2, SLC25A30, SLC26A6 and 2 moreinner side of the membrane, outer side of the membrane, extracellular space, cytosolOne of 2 routes

• a quinolReach from here →
  1. oxalate(in) + sulfate(out) = oxalate(out) + sulfate(in)
  2. transport of malate and sulfate (cytosol to mitochondria)
  3. (S)-malate + a quinone = enol-oxaloacetate + a quinol

  Catalysed by SLC25A14, SLC26A2, SLC25A30, SLC26A6 and 4 moreinner side of the membrane, outer side of the membrane, mitochondrial matrix, cytosol

• hypochlorous acidReach from here →
  1. oxalate(in) + sulfate(out) = oxalate(out) + sulfate(in)
  2. transport of chloride and sulfate (cytosol to extracellular)
  3. Peroxidase

  Catalysed by SLC25A14, SLC26A2, SLC25A30, SLC26A6 and 2 moreinner side of the membrane, outer side of the membrane, extracellular space, cytosolOne of 4 routes

• potassium atomReach from here →
  1. oxalate(in) + sulfate(out) = oxalate(out) + sulfate(in)
  2. transport of chloride and sulfate (cytosol to extracellular)
  3. transport of chloride (cytosol to extracellular)

  Catalysed by SLC25A14, SLC26A2, SLC25A30, SLC26A6 and 3 moreinner side of the membrane, outer side of the membrane, extracellular space, cytosolOne of 3 routes

• 3beta-hydroxyandrost-5-en-17-oneReach from here →
  1. oxalate(in) + sulfate(out) = oxalate(out) + sulfate(in)
  2. dehydroepiandrosterone 3-sulfate + H2O = 3beta-hydroxyandrost-5-en-17-one + sulfate + H(+)
  3. 3beta-Hydroxyandrost-5-en-17-one 3-sulfate sulfohydrolase

  Catalysed by SLC25A14, SLC26A2, SLC25A30, SLC26A6 and 2 moreinner side of the membrane, outer side of the membrane, cytosolOne of 3 routes

• K(+)Reach from here →
  1. oxalate(in) + sulfate(out) = oxalate(out) + sulfate(in)
  2. L-aspartate(in) + sulfate(out) = L-aspartate(out) + sulfate(in)
  3. K(+)(in) + L-aspartate(out) + 3 Na(+)(out) + H(+)(out) = K(+)(out) + L-aspartate(in) + 3 Na(+)(in) + H(+)(in)

  Catalysed by SLC25A14, SLC26A2, SLC25A30, SLC26A6 and 6 moreinner side of the membrane, outer side of the membraneOne of 4 routes

• Asp-tRNA(Asp)Reach from here →
  1. oxalate(in) + sulfate(out) = oxalate(out) + sulfate(in)
  2. L-aspartate(in) + sulfate(out) = L-aspartate(out) + sulfate(in)
  3. L-Aspartate:tRNA(Asp) ligase (AMP-forming)

  Catalysed by SLC25A14, SLC26A2, SLC25A30, SLC26A6 and 2 moreinner side of the membrane, outer side of the membrane, cytosol

• hydrogen sulfideReach from here →
  1. oxalate(in) + sulfate(out) = oxalate(out) + sulfate(in)
  2. thiosulfate(in) + sulfate(out) = thiosulfate(out) + sulfate(in)
  3. 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific) (H2S2O3)

  Catalysed by SLC25A14, SLC26A2, SLC25A30, SLC26A6 and 2 moreinner side of the membrane, outer side of the membrane, cytosolOne of 2 routes

• formic acidReach from here →
  1. oxalate(in) + formate(out) = oxalate(out) + formate(in)
  2. 1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + O2 = 3-(methylsulfanyl)propanoate + CO + formate + 2 H(+)
  3. acireductone dioxygenase

  Catalysed by SLC26A6, ADI1inner side of the membrane, outer side of the membrane, cytosolOne of 5 routes

• citric acidReach from here →
  1. oxalate(in) + sulfate(out) = oxalate(out) + sulfate(in)
  2. transport of malate and sulfate (cytosol to mitochondria)
  3. Citrate Transport, Mitochondrial

  Catalysed by SLC25A14, SLC26A2, SLC25A30, SLC26A6 and 3 moreinner side of the membrane, outer side of the membrane, mitochondrial matrix, cytosolOne of 10 routes