CHEBI:240943

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

496 compounds within 3 steps: 3 in 1, 88 in 2, 405 in 3

Two steps

5,6,7,8-tetrahydrofolic acidReach from here →
1. glycine N-acyltransferase (2-methylbutyryl-CoA)
2. 5,10-Methylenetetrahydrofolate:glycine hydroxymethyltransferase
Catalysed by GLYAT, GLYATL2, GLYATL1, SHMT1mitochondrial matrix, cytosolOne of 2 routes
hypochlorous acidReach from here →
1. 2-Methylbutyrylglycine Transport, Extracellular
2. Peroxidase
Catalysed by SLC6A5, LPOextracellular space, cytosolOne of 4 routes
potassium atomReach from here →
1. 2-Methylbutyrylglycine Transport, Extracellular
2. transport of chloride (cytosol to extracellular)
Catalysed by SLC6A5, SLC12A2, SLC12A1extracellular space, cytosolOne of 2 routes
phenylacetylglycineReach from here →
1. glycine N-acyltransferase (2-methylbutyryl-CoA)
2. phenylacetyl-CoA:glycine N-phenylacetyltransferase
Catalysed by GLYAT, GLYATL2, GLYATL1mitochondrial matrix, cytosolOne of 3 routes
CHEBI:28666Reach from here →
1. glycine N-acyltransferase (2-methylbutyryl-CoA)
2. LTD4 hydrolysis
Catalysed by GLYAT, GLYATL2, GLYATL1mitochondrial matrix, cytosol
Gly-tRNA(Gly)Reach from here →
1. glycine N-acyltransferase (2-methylbutyryl-CoA)
2. glycine:tRNA(Gly) ligase (AMP-forming)
Catalysed by GLYAT, GLYATL2, GLYATL1, GARS1mitochondrial matrix, cytosol
glycocholateReach from here →
1. glycine N-acyltransferase (2-methylbutyryl-CoA)
2. bile acid-CoA: amino acid N-acyltransferase
Catalysed by GLYAT, GLYATL2, GLYATL1, BAATmitochondrial matrix, peroxisomeOne of 3 routes
formic acidReach from here →
1. 2-Methylbutyrylglycine Transport, Extracellular
2. transport of chloride and formate (cytosol to extracellular)
Catalysed by SLC6A5, SLC26A4extracellular space, cytosolOne of 2 routes
malonic acidReach from here →
1. 2-Methylbutyrylglycine Transport, Extracellular
2. Malonate Transport, Antiport with Chloride
Catalysed by SLC6A5extracellular space, cytosolOne of 2 routes
5-aminolevulinateReach from here →
1. glycine N-acyltransferase (2-methylbutyryl-CoA)
2. succinyl-CoA + glycine + H(+) = 5-aminolevulinate + CO2 + CoA
Catalysed by GLYAT, GLYATL2, GLYATL1, ALAS1 and 1 moremitochondrial matrix
glycochenodeoxycholateReach from here →
1. glycine N-acyltransferase (2-methylbutyryl-CoA)
2. chenodeoxycholoyl-CoA + glycine = glycochenodeoxycholate + CoA + H(+)
Catalysed by GLYAT, GLYATL2, GLYATL1, BAATmitochondrial matrix
glycochenodeoxycholic acidReach from here →
1. glycine N-acyltransferase (2-methylbutyryl-CoA)
2. bile acid-CoA: amino acid N-acyltransferase
Catalysed by GLYAT, GLYATL2, GLYATL1, BAATmitochondrial matrix, peroxisomeOne of 3 routes
glyoxylateReach from here →
1. glycine N-acyltransferase (2-methylbutyryl-CoA)
2. glycine + 2-oxoglutarate = glyoxylate + L-glutamate
Catalysed by GLYAT, GLYATL2, GLYATL1, AADATmitochondrial matrixOne of 11 routes
glycolithocholic acidReach from here →
1. glycine N-acyltransferase (2-methylbutyryl-CoA)
2. bile acid-CoA:amino acid N-acyltransferase (glycine)
Catalysed by GLYAT, GLYATL2, GLYATL1, BAATmitochondrial matrix, cytosolOne of 2 routes
L-2-amino-3-oxobutanoic acidReach from here →
1. glycine N-acyltransferase (2-methylbutyryl-CoA)
2. Acetyl-CoA:glycine C-acetyltransferase
Catalysed by GLYAT, GLYATL2, GLYATL1, GCATmitochondrial matrix
L-ornithineReach from here →
1. glycine N-acyltransferase (2-methylbutyryl-CoA)
2. L-Arginine:glycine amidinotransferase
Catalysed by GLYAT, GLYATL2, GLYATL1, GATMmitochondrial matrix, cytosolOne of 5 routes
S(8)-aminomethyldihydrolipoamideReach from here →
1. glycine N-acyltransferase (2-methylbutyryl-CoA)
2. dihydrolipoyl dehydrogenase ([protein]-N6-(lipoyl)lysine)
Catalysed by GLYAT, GLYATL2, GLYATL1, GLDC and 1 moremitochondrial matrix
taurineReach from here →
1. 2-Methylbutyrylglycine Transport, Extracellular
2. Neurotransmitter:Sodium Symporter (Nss) Tcdb:2.A.22.3.3
Catalysed by SLC6A5, SLC6A6extracellular space, cytosolOne of 2 routes
sarcosineReach from here →
1. glycine N-acyltransferase (2-methylbutyryl-CoA)
2. sarcosine + O2 + H2O = formaldehyde + glycine + H2O2
Catalysed by GLYAT, GLYATL2, GLYATL1, PIPOXmitochondrial matrixOne of 2 routes
(6S)-5,6,7,8-tetrahydrofolateReach from here →
1. glycine N-acyltransferase (2-methylbutyryl-CoA)
2. (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O = (6S)-5,6,7,8-tetrahydrofolate + L-serine
Catalysed by GLYAT, GLYATL2, GLYATL1, SHMT1 and 1 moremitochondrial matrix
an N-acylglycineReach from here →
1. glycine N-acyltransferase (2-methylbutyryl-CoA)
2. an acyl-CoA + glycine = an N-acylglycine + CoA + H(+)
Catalysed by GLYAT, GLYATL2, GLYATL1, GLYATL3mitochondrial matrix
guanidinoacetateReach from here →
1. glycine N-acyltransferase (2-methylbutyryl-CoA)
2. L-Arginine:glycine amidinotransferase
Catalysed by GLYAT, GLYATL2, GLYATL1, GATMmitochondrial matrix, cytosolOne of 3 routes
L-methionineReach from here →
1. glycine N-acyltransferase (2-methylbutyryl-CoA)
2. transport of glycine and methionine (cytosol to extracellular)
Catalysed by GLYAT, GLYATL2, GLYATL1, SLC7A5mitochondrial matrix, extracellular space, cytosolOne of 7 routes
L-tryptophanReach from here →
1. glycine N-acyltransferase (2-methylbutyryl-CoA)
2. transport of glycine and tryptophan (cytosol to extracellular)
Catalysed by GLYAT, GLYATL2, GLYATL1, SLC7A5mitochondrial matrix, extracellular space, cytosolOne of 7 routes
glutathioneReach from here →
1. glycine N-acyltransferase (2-methylbutyryl-CoA)
2. gamma-L-glutamyl-L-cysteine + glycine + ATP = glutathione + ADP + phosphate + H(+)
Catalysed by GLYAT, GLYATL2, GLYATL1, GSSmitochondrial matrix
beta-alanineReach from here →
1. 2-Methylbutyrylglycine Transport, Extracellular
2. transport of beta-alanine and chloride (cytosol to extracellular)
Catalysed by SLC6A5, SLC6A6, SLC6A14extracellular space, cytosolOne of 2 routes
L-alanineReach from here →
1. glycine N-acyltransferase (2-methylbutyryl-CoA)
2. transport of alanine and glycine (cytosol to extracellular)
Catalysed by GLYAT, GLYATL2, GLYATL1, SLC3A2 and 2 moremitochondrial matrix, extracellular space, cytosolOne of 8 routes
leukotriene C4Reach from here →
1. glycine N-acyltransferase (2-methylbutyryl-CoA)
2. leukotriene C4 hydrolysis
Catalysed by GLYAT, GLYATL2, GLYATL1mitochondrial matrix, cytosol
L-asparagineReach from here →
1. glycine N-acyltransferase (2-methylbutyryl-CoA)
2. transport of asparagine and glycine (cytosol to extracellular)
Catalysed by GLYAT, GLYATL2, GLYATL1mitochondrial matrix, extracellular space, cytosolOne of 6 routes
L-phenylalanineReach from here →
1. glycine N-acyltransferase (2-methylbutyryl-CoA)
2. transport of glycine and phenylalanine (cytosol to extracellular)
Catalysed by GLYAT, GLYATL2, GLYATL1, SLC7A5mitochondrial matrix, extracellular space, cytosolOne of 9 routes
L-tyrosineReach from here →
1. glycine N-acyltransferase (2-methylbutyryl-CoA)
2. L-tyrosine + glyoxylate = 3-(4-hydroxyphenyl)pyruvate + glycine
Catalysed by GLYAT, GLYATL2, GLYATL1, AADATmitochondrial matrix
N(omega),N(omega)-dimethyl-L-arginineReach from here →
1. glycine N-acyltransferase (2-methylbutyryl-CoA)
2. N(omega),N(omega)-dimethyl-L-arginine + glyoxylate = 5-(3,3-dimethylguanidino)-2-oxopentanoate + glycine
Catalysed by GLYAT, GLYATL2, GLYATL1, AGXT2mitochondrial matrix
N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycineReach from here →
1. glycine N-acyltransferase (2-methylbutyryl-CoA)
2. (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + glycine = N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + CoA + H(+)
Catalysed by GLYAT, GLYATL2, GLYATL1mitochondrial matrixOne of 2 routes
4-aminobutanoateReach from here →
1. 2-Methylbutyrylglycine Transport, Extracellular
2. transport of 4-aminobutyrate and chloride (cytosol to extracellular)
Catalysed by SLC6A5, SLC6A12extracellular space, cytosolOne of 4 routes
N-benzoylglycineReach from here →
1. glycine N-acyltransferase (2-methylbutyryl-CoA)
2. Hippurate (Benzoylglycinate) Formation
Catalysed by GLYAT, GLYATL2, GLYATL1mitochondrial matrixOne of 2 routes
(2S)-2-aminobutanoateReach from here →
1. glycine N-acyltransferase (2-methylbutyryl-CoA)
2. (2S)-2-aminobutanoate + glyoxylate = 2-oxobutanoate + glycine
Catalysed by GLYAT, GLYATL2, GLYATL1, AGXT2mitochondrial matrix
glycodeoxycholateReach from here →
1. glycine N-acyltransferase (2-methylbutyryl-CoA)
2. Glycodeoxycholate amidohydrolase
Catalysed by GLYAT, GLYATL2, GLYATL1mitochondrial matrix, cytosolOne of 2 routes
N-tetradecanoylglycineReach from here →
1. glycine N-acyltransferase (2-methylbutyryl-CoA)
2. tetradecanoyl-CoA + glycine = N-tetradecanoylglycine + CoA + H(+)
Catalysed by GLYAT, GLYATL2, GLYATL1mitochondrial matrix
N-eicosanoylglycinateReach from here →
1. glycine N-acyltransferase (2-methylbutyryl-CoA)
2. eicosanoyl-CoA + glycine = N-eicosanoylglycinate + CoA + H(+)
Catalysed by GLYAT, GLYATL2, GLYATL1, BAATmitochondrial matrix
N-docosanoylglycineReach from here →
1. glycine N-acyltransferase (2-methylbutyryl-CoA)
2. docosanoyl-CoA + glycine = N-docosanoylglycine + CoA + H(+)
Catalysed by GLYAT, GLYATL2, GLYATL1, BAATmitochondrial matrix
N-hexacosanoylglycineReach from here →
1. glycine N-acyltransferase (2-methylbutyryl-CoA)
2. hexacosanoyl-CoA + glycine = N-hexacosanoylglycine + CoA + H(+)
Catalysed by GLYAT, GLYATL2, GLYATL1, BAATmitochondrial matrix

Three steps

beta-carbolineReach from here →
Catalysed by GLYAT, GLYATL2, GLYATL1, SLC7A5mitochondrial matrix, extracellular space, cytosol
2-hydroxybutyric acidReach from here →