pyruvate

Three steps

• prostaglandin J2-S-(S)-glutathioneReach from here →
  1. (S)-Lactate:NAD+ oxidoreductase
  2. Transport of Prostaglandin J2, Lactate Antiport
  3. prostaglandin J2 + glutathione = prostaglandin J2-S-(S)-glutathione

  Catalysed by LDHB, LDHAL6B, GSTP1, GSTM1mitochondrial matrix, extracellular space, cytosol

• 13-hydroxy-(9Z,11E)-octadecadienoateReach from here →
  1. (R)-3-Amino-2-methylpropanoate:pyruvate aminotransferase
  2. Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O
  3. (9Z,12Z)-octadecadienoate + AH2 + O2 = 13-hydroxy-(9Z,11E)-octadecadienoate + A + H2O

  Catalysed by AGXT2, MOCOS, PTGS2mitochondrial matrix

• 9-hydroxy-(10E,12Z)-octadecadienoateReach from here →
  1. (R)-3-Amino-2-methylpropanoate:pyruvate aminotransferase
  2. Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O
  3. (9Z,12Z)-octadecadienoate + AH2 + O2 = 9-hydroxy-(10E,12Z)-octadecadienoate + A + H2O

  Catalysed by AGXT2, MOCOS, PTGS2mitochondrial matrix

• hypothiocyanous acidReach from here →
  1. 2-oxo-3-sulfanylpropanoate + [thioredoxin]-dithiol = [thioredoxin]-disulfide + hydrogen sulfide + pyruvate + H(+)
  2. 3-mercaptopyruvate sulfurtransferase (hydrogen-cyanide)
  3. Dihydrolipoyl Dehydrogenase

  Catalysed by MPST, TST, LPOcytosol, extracellular spaceOne of 4 routes

• 2,4-dinitrophenyl-S-glutathioneReach from here →
  1. (S)-Lactate:NAD+ oxidoreductase
  2. Transport of Prostaglandin A2, Lactate Antiport
  3. transport of prostaglandin A2 (cytosol to extracellular)

  Catalysed by LDHB, LDHAL6B, SLCO1B1mitochondrial matrix, extracellular space, cytosolOne of 16 routes

• N-(9Z-octadecenoyl)glycineReach from here →
  1. (R)-3-Amino-2-methylpropanoate:pyruvate aminotransferase
  2. L-Alanine:glyoxylate aminotransferase
  3. (9Z)-octadecenoyl-CoA + glycine = N-(9Z-octadecenoyl)glycine + CoA + H(+)

  Catalysed by AGXT2, AGXT, GLYATL3, GLYATL2mitochondrial matrix

• N-(9Z-octadecenoyl)-L-phenylalanineReach from here →
  1. (R)-3-Amino-2-methylpropanoate:pyruvate aminotransferase
  2. transport of alanine and phenylalanine (cytosol to extracellular)
  3. L-phenylalanine + (9Z)-octadecenoate = N-(9Z-octadecenoyl)-L-phenylalanine + H2O

  Catalysed by AGXT2, SLC7A5, PM20D1mitochondrial matrix, extracellular space, cytosol

• N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-L-phenylalanineReach from here →
  1. (R)-3-Amino-2-methylpropanoate:pyruvate aminotransferase
  2. transport of alanine and phenylalanine (cytosol to extracellular)
  3. (5Z,8Z,11Z,14Z)-eicosatetraenoate + L-phenylalanine = N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-L-phenylalanine + H2O

  Catalysed by AGXT2, SLC7A5, PM20D1mitochondrial matrix, extracellular space, cytosol

• N-(9Z-octadecenoyl)-L-leucineReach from here →
  1. (R)-3-Amino-2-methylpropanoate:pyruvate aminotransferase
  2. transport of alanine and leucine (cytosol to extracellular)
  3. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate

  Catalysed by AGXT2, SLC7A5, PM20D1mitochondrial matrix, extracellular space, cytosol

• N-octadecanoylglycineReach from here →
  1. (R)-3-Amino-2-methylpropanoate:pyruvate aminotransferase
  2. L-Alanine:glyoxylate aminotransferase
  3. octadecanoyl-CoA + glycine = N-octadecanoylglycine + CoA + H(+)

  Catalysed by AGXT2, AGXT, GLYATL2mitochondrial matrix

• N-(9Z-hexadecenoyl)-glycineReach from here →
  1. (R)-3-Amino-2-methylpropanoate:pyruvate aminotransferase
  2. L-Alanine:glyoxylate aminotransferase
  3. (9Z)-hexadecenoyl-CoA + glycine = N-(9Z-hexadecenoyl)-glycine + CoA + H(+)

  Catalysed by AGXT2, AGXT, GLYATL2mitochondrial matrix

• all-trans-4-oxoretinoateReach from here →
  1. transport of pyruvate and retinoate (cytosol to extracellular)
  2. cytochrome P450 (retinoate)
  3. cytochrome P450 (4-hydroxy-all-trans-retinoate)

  Catalysed by SLC16A4, SLC16A5, SLC16A3, SLC16A7 and 4 moreextracellular space, cytosolOne of 3 routes

• an N-acetyl-alpha-neuraminyl-(2->6)-beta-D-galactosyl derivativeReach from here →
  1. N-Acetylneuraminate pyruvate-lyase (N-acetyl-D-mannosamine-forming)
  2. CTP:N-acetylneuraminate cytidylyltransferase
  3. a beta-D-galactoside + CMP-N-acetyl-beta-neuraminate = an N-acetyl-alpha-neuraminyl-(2->6)-beta-D-galactosyl derivative + CMP + H(+)

  Catalysed by NPL, CMAS, ST6GAL1, ST6GAL2cytosol, nucleus

• an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivativeReach from here →
  1. N-Acetylneuraminate pyruvate-lyase (N-acetyl-D-mannosamine-forming)
  2. CTP:N-acetylneuraminate cytidylyltransferase
  3. a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + CMP-N-acetyl-beta-neuraminate = an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + CMP + H(+)

  Catalysed by NPL, CMAS, ST3GAL3, ST3GAL4 and 1 morecytosol, nucleus

• cholesterol sulfateReach from here →
  1. (S)-malate + NAD(+) = pyruvate + CO2 + NADH
  2. transport of malate and sulfate (cytosol to mitochondria)
  3. Steryl-Sulfatase

  Catalysed by ME2, SLC25A10, STSmitochondrial matrix, cytosol, Golgi apparatusOne of 2 routes

• an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl derivativeReach from here →
  1. N-Acetylneuraminate pyruvate-lyase (N-acetyl-D-mannosamine-forming)
  2. CTP:N-acetylneuraminate cytidylyltransferase
  3. a beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl derivative + CMP-N-acetyl-beta-neuraminate = an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl derivative + CMP + H(+)

  Catalysed by NPL, CMAS, ST3GAL4cytosol, nucleus

• (13R)-hydroxy-(9Z,11E)-octadecadienoateReach from here →
  1. (R)-3-Amino-2-methylpropanoate:pyruvate aminotransferase
  2. Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O
  3. (9Z,12Z)-octadecadienoate + AH2 + O2 = (13R)-hydroxy-(9Z,11E)-octadecadienoate + A + H2O

  Catalysed by AGXT2, MOCOS, PTGS1, PTGS2mitochondrial matrix

• 5alpha-dihydrotestosterone sulfateReach from here →
  1. (S)-malate + NAD(+) = pyruvate + CO2 + NADH
  2. transport of malate and sulfate (cytosol to mitochondria)
  3. steroid sulfatase (5-alpha-dihydrotestosterone)

  Catalysed by ME2, SLC25A10, STSmitochondrial matrix, cytosolOne of 3 routes

• 2-[(11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoyl]-sn-glycero-3-phosphocholineReach from here →
  1. (R)-3-Amino-2-methylpropanoate:pyruvate aminotransferase
  2. Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O
  3. 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + AH2 + O2 = 2-[(11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoyl]-sn-glycero-3-phosphocholine + A + H2O

  Catalysed by AGXT2, MOCOS, PTGS2mitochondrial matrix

• 2-[(15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-sn-glycero-3-phosphocholineReach from here →
  1. (R)-3-Amino-2-methylpropanoate:pyruvate aminotransferase
  2. Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O
  3. 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + AH2 + O2 = 2-[(15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-sn-glycero-3-phosphocholine + A + H2O

  Catalysed by AGXT2, MOCOS, PTGS2mitochondrial matrix

• 2-[(15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-sn-glycero-3-phosphocholineReach from here →
  1. (R)-3-Amino-2-methylpropanoate:pyruvate aminotransferase
  2. Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O
  3. 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + AH2 + O2 = 2-[(15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-sn-glycero-3-phosphocholine + A + H2O

  Catalysed by AGXT2, MOCOS, PTGS2mitochondrial matrix

• an N-acyl-aromatic L-alpha-amino acidReach from here →
  1. a 3-acylpyruvate + H2O = a carboxylate + pyruvate + H(+)
  2. a 3-acylpyruvate + H2O = a carboxylate + pyruvate + H(+)
  3. an N-acyl-aromatic L-alpha-amino acid + H2O = an aromatic L-alpha-amino acid + a carboxylate

  Catalysed by FAHD1, PM20D1, ACY3

• 2-(prostaglandin H2)-sn-glycero-3-phosphoethanolamineReach from here →
  1. (R)-3-Amino-2-methylpropanoate:pyruvate aminotransferase
  2. Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O
  3. 2-(prostaglandin G2)-sn-glycero-3-phosphoethanolamine + AH2 = 2-(prostaglandin H2)-sn-glycero-3-phosphoethanolamine + A + H2O

  Catalysed by AGXT2, MOCOS, PTGS2mitochondrial matrix

• 2-(prostaglandin H2)-sn-glycero-3-phosphocholineReach from here →
  1. (R)-3-Amino-2-methylpropanoate:pyruvate aminotransferase
  2. Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O
  3. 2-(prostaglandin G2)-sn-glycero-3-phosphocholine + AH2 = 2-(prostaglandin H2)-sn-glycero-3-phosphocholine + A + H2O

  Catalysed by AGXT2, MOCOS, PTGS2mitochondrial matrix

• N-(4-oxoglutaryl)-L-cysteinylglycineReach from here →
  1. (R)-3-Amino-2-methylpropanoate:pyruvate aminotransferase
  2. gamma-glutamyltransferase (alanine)
  3. N-(4-oxoglutaryl)-L-cysteinylglycine + H2O = L-cysteinylglycine + 2-oxoglutarate

  Catalysed by AGXT2, GGTLC3, GGT1, GGT5 and 4 moremitochondrial matrix, cytosol

• all-trans-4-hydroxy-4-O-(beta-D-glucuronide)-retinoateReach from here →
  1. transport of pyruvate and retinoate (cytosol to extracellular)
  2. cytochrome P450 (retinoate)
  3. all-trans-4-hydroxyretinoate + UDP-alpha-D-glucuronate = all-trans-4-hydroxy-4-O-(beta-D-glucuronide)-retinoate + UDP + H(+)

  Catalysed by SLC16A4, SLC16A5, SLC16A3, SLC16A7 and 4 moreextracellular space, cytosol

• an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivativeReach from here →
  1. N-Acetylneuraminate pyruvate-lyase (N-acetyl-D-mannosamine-forming)
  2. CTP:N-acetylneuraminate cytidylyltransferase
  3. a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + CMP-N-acetyl-beta-neuraminate = an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + CMP + H(+)

  Catalysed by NPL, CMAS, ST3GAL1, ST3GAL4 and 1 morecytosol, nucleus

• an N-acetyl-alpha-neuraminyl-(2->8)-N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl derivativeReach from here →
  1. N-Acetylneuraminate pyruvate-lyase (N-acetyl-D-mannosamine-forming)
  2. CTP:N-acetylneuraminate cytidylyltransferase
  3. an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl derivative + CMP-N-acetyl-beta-neuraminate = an N-acetyl-alpha-neuraminyl-(2->8)-N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl derivative + CMP + H(+)

  Catalysed by NPL, CMAS, ST8SIA3, ST8SIA1cytosol, nucleus

• an aryl sulfateReach from here →
  1. (S)-malate + NAD(+) = pyruvate + CO2 + NADH
  2. transport of malate and sulfate (cytosol to mitochondria)
  3. an aryl sulfate + H2O = a phenol + sulfate + H(+)

  Catalysed by ME2, SLC25A10, ARSL, ARSF and 4 moremitochondrial matrix, cytosol

• a globoside MSGGReach from here →
  1. N-Acetylneuraminate pyruvate-lyase (N-acetyl-D-mannosamine-forming)
  2. CTP:N-acetylneuraminate cytidylyltransferase
  3. a globoside GalGb4Cer + CMP-N-acetyl-beta-neuraminate = a globoside MSGG + CMP + H(+)

  Catalysed by NPL, CMAS, ST3GAL2cytosol, nucleus

• a globoside DSGGReach from here →
  1. N-Acetylneuraminate pyruvate-lyase (N-acetyl-D-mannosamine-forming)
  2. CTP:N-acetylneuraminate cytidylyltransferase
  3. a globoside MSGG + CMP-N-acetyl-beta-neuraminate = a globoside DSGG + CMP + H(+)

  Catalysed by NPL, CMAS, ST6GALNAC3, ST6GALNAC6cytosol, nucleus

• a beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminyl-(2->6)]-N-acetyl-alpha-D-galactosaminyl derivativeReach from here →
  1. N-Acetylneuraminate pyruvate-lyase (N-acetyl-D-mannosamine-forming)
  2. CTP:N-acetylneuraminate cytidylyltransferase
  3. a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + CMP-N-acetyl-beta-neuraminate = a beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminyl-(2->6)]-N-acetyl-alpha-D-galactosaminyl derivative + CMP + H(+)

  Catalysed by NPL, CMAS, ST6GALNAC1, ST6GALNAC2cytosol, nucleus

• 2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
  1. transport of acetate and pyruvate (cytosol to extracellular)
  2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
  3. 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + N-(acetyl)-sphing-4-enine = 2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + 1-octadecanoyl-N-(acetyl)-sphing-4-enine

  Catalysed by SLC16A4, SLC16A5, SLC16A3, SLC16A7 and 3 moreextracellular space, cytosol

• N-hexadecanoylglycineReach from here →
  1. (R)-3-Amino-2-methylpropanoate:pyruvate aminotransferase
  2. L-Alanine:glyoxylate aminotransferase
  3. hexadecanoyl-CoA + glycine = N-hexadecanoylglycine + CoA + H(+)

  Catalysed by AGXT2, AGXT, GLYATL3mitochondrial matrix

• N-dodecanoylglycineReach from here →
  1. (R)-3-Amino-2-methylpropanoate:pyruvate aminotransferase
  2. L-Alanine:glyoxylate aminotransferase
  3. dodecanoyl-CoA + glycine = N-dodecanoylglycine + CoA + H(+)

  Catalysed by AGXT2, AGXT, GLYATL2mitochondrial matrix

• N-decanoylglycineReach from here →
  1. (R)-3-Amino-2-methylpropanoate:pyruvate aminotransferase
  2. L-Alanine:glyoxylate aminotransferase
  3. decanoyl-CoA + glycine = N-decanoylglycine + CoA + H(+)

  Catalysed by AGXT2, AGXT, GLYATL2mitochondrial matrix

• N-octanoylglycineReach from here →
  1. (R)-3-Amino-2-methylpropanoate:pyruvate aminotransferase
  2. L-Alanine:glyoxylate aminotransferase
  3. octanoyl-CoA + glycine = N-octanoylglycine + CoA + H(+)

  Catalysed by AGXT2, AGXT, GLYATL2mitochondrial matrix

• N-octanoyl-(2S)-hydroxyglycineReach from here →
  1. (S)-malate + NAD(+) = pyruvate + CO2 + NADH
  2. glyoxylate + acetyl-CoA + H2O = (S)-malate + CoA + H(+)
  3. N-octanoyl-(2S)-hydroxyglycine = octanamide + glyoxylate

  Catalysed by ME2, CLYBL, PAM

• N-decanoyl-(2S)-hydroxyglycineReach from here →
  1. (S)-malate + NAD(+) = pyruvate + CO2 + NADH
  2. glyoxylate + acetyl-CoA + H2O = (S)-malate + CoA + H(+)
  3. N-decanoyl-(2S)-hydroxyglycine = decanamide + glyoxylate

  Catalysed by ME2, CLYBL, PAM

• N-dodecanoyl-(2S)-hydroxyglycineReach from here →
  1. (S)-malate + NAD(+) = pyruvate + CO2 + NADH
  2. glyoxylate + acetyl-CoA + H2O = (S)-malate + CoA + H(+)
  3. N-dodecanoyl-(2S)-hydroxyglycine = dodecanamide + glyoxylate

  Catalysed by ME2, CLYBL, PAM

• N-tetradecanoyl-(2S)-hydroxyglycineReach from here →
  1. (S)-malate + NAD(+) = pyruvate + CO2 + NADH
  2. glyoxylate + acetyl-CoA + H2O = (S)-malate + CoA + H(+)
  3. N-tetradecanoyl-(2S)-hydroxyglycine = tetradecamide + glyoxylate

  Catalysed by ME2, CLYBL, PAM

• N-(9Z-octadecenoyl)-(2S)-hydroxyglycineReach from here →
  1. (S)-malate + NAD(+) = pyruvate + CO2 + NADH
  2. glyoxylate + acetyl-CoA + H2O = (S)-malate + CoA + H(+)
  3. N-(9Z-octadecenoyl)-(2S)-hydroxyglycine = (9Z)-octadecenamide + glyoxylate

  Catalysed by ME2, CLYBL, PAM

• N-(9Z,12Z,15Z)-octadecatrienoyl-(2S)-hydroxyglycineReach from here →
  1. (S)-malate + NAD(+) = pyruvate + CO2 + NADH
  2. glyoxylate + acetyl-CoA + H2O = (S)-malate + CoA + H(+)
  3. N-(9Z,12Z,15Z)-octadecatrienoyl-(2S)-hydroxyglycine = (9Z,12Z,15Z)-octadecatrienamide + glyoxylate

  Catalysed by ME2, CLYBL, PAM

• D-histidineReach from here →
  1. (R)-3-Amino-2-methylpropanoate:pyruvate aminotransferase
  2. transport of alanine and ornithine (cytosol to extracellular)
  3. D-histidine(in) + L-ornithine(out) + H(+)(in) = D-histidine(out) + L-ornithine(in) + H(+)(out)

  Catalysed by AGXT2, SLC7A6, SLC25A2mitochondrial matrix, extracellular space, cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

• L-homoarginineReach from here →
  1. (R)-3-Amino-2-methylpropanoate:pyruvate aminotransferase
  2. transport of alanine and arginine (cytosol to extracellular)
  3. L-homoarginine(in) + L-arginine(out) = L-homoarginine(out) + L-arginine(in)

  Catalysed by AGXT2, SLC7A6, SLC25A29mitochondrial matrix, extracellular space, cytosol, inner side of the membrane, outer side of the membraneOne of 4 routes

• L-homocarnosineReach from here →
  1. (R)-3-Amino-2-methylpropanoate:pyruvate aminotransferase
  2. transport of alanine and histidine (cytosol to extracellular)
  3. Formation of homocarnosine

  Catalysed by AGXT2, SLC7A6, CARNS1mitochondrial matrix, extracellular space, cytosol

• N(1)-(5-phospho-beta-D-ribosyl)glycinamideReach from here →
  1. (R)-3-Amino-2-methylpropanoate:pyruvate aminotransferase
  2. L-Alanine:glyoxylate aminotransferase
  3. 5-phospho-beta-D-ribosylamine + glycine + ATP = N(1)-(5-phospho-beta-D-ribosyl)glycinamide + ADP + phosphate + H(+)

  Catalysed by AGXT2, AGXT, GARTmitochondrial matrix

• L-cystine-bis-glycineReach from here →
  1. (R)-3-Amino-2-methylpropanoate:pyruvate aminotransferase
  2. L-Alanine:glyoxylate aminotransferase
  3. L-cystine-bis-glycine + 2 H2O = L-cystine + 2 glycine

  Catalysed by AGXT2, AGXT, DPEP1, DPEP2mitochondrial matrixOne of 3 routes

• a neolactoside VI(3)-alpha-NeuNAc-nLc6Cer(d18:1(4E))Reach from here →
  1. N-Acetylneuraminate pyruvate-lyase (N-acetyl-D-mannosamine-forming)
  2. CTP:N-acetylneuraminate cytidylyltransferase
  3. a neolactoside nLc6Cer(d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a neolactoside VI(3)-alpha-NeuNAc-nLc6Cer(d18:1(4E)) + CMP + H(+)

  Catalysed by NPL, CMAS, ST3GAL6cytosol, nucleus

• 2-nonadioyl-sn-glycero-3-phosphocholineReach from here →
  1. transport of acetate and pyruvate (cytosol to extracellular)
  2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
  3. 1-hexadecanoyl-2-nonadioyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 2-nonadioyl-sn-glycero-3-phosphocholine + 1-hexadecanoyl-N-(acetyl)-sphing-4-enine

  Catalysed by SLC16A4, SLC16A5, SLC16A3, SLC16A7 and 3 moreextracellular space, cytosol