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Proteins/UNIPROT:P07737
Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR..
Function from UniProtKB (P07737), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
2 rows
644 statements
644 statements · 4 reference databases · Subject: PFN1 · Sources: gene ontology, Hetionet, Reactome, WikiPathways · Rows fetched: 300
2 names
Resolves to: PFN1