Loading the page.
Proteins/UNIPROT:Q5VWQ0
Histone demethylase that specifically demethylates dimethylated 'Lys-20' of histone H4 (H4K20me2) and trimethylated 'Lys-20' of histone H4 (H4K20me3) into monomethyl H4K20 (H4K20me1) thereby modulating chromosome architecture. May play a critical role in regulating H4K20 methylation during spermatogenesis..
Function from UniProtKB (Q5VWQ0), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
21 statements
21 statements · 3 reference databases · Subject: RSBN1 · Sources: Bgee, Hetionet, UniProt
2 reactions
N(6),N(6)-dimethyl-L-lysyl(20)-[histone H4]+2-oxoglutarate(2-)+dioxygenN(6)-methyl-L-lysyl(20)-[histone H4]+formaldehyde+succinate(2-)+carbon dioxide
Catalysed by KDM1A or RAD23A or RAD23B or RSBN1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:85907CC BY 4.0Reference data
N(6),N(6),N(6)-trimethyl-L-lysyl(20)-[histone H4]+2-oxoglutarate(2-)
2 names
Resolves to: RSBN1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:85911CC BY 4.0Reference data