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Proteins/UNIPROT:Q9UBT2
The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2..
Function from UniProtKB (Q9UBT2), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
2 rows
41 statements
41 statements · 3 reference databases · Subject: UBA2 · Sources: gene ontology, Hetionet, Reactome
1 reaction
5 names
Resolves to: UBA2
Reaction pageLeft to rightBalance undeterminableEC 2.3.2.23, 2.3.2.27, 6.2.1.45cytosol
Human-GEM MAR09491CC BY 4.0Reference data