Proteins/UNIPROT:Q8IZM9

SLC38A6

ProteinUNIPROT:Q8IZM9Solute carrier family 38 member 6

Amino acid transporter with an apparent selectivity for L-glutamine and L-glutamate. May facilitate glutamine uptake in excitatory neurons. The transport mechanism remains to be elucidated..

Function from UniProtKB (Q8IZM9), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

10 statements

10 statements · 2 reference databases · Subject: SLC38A6 · Sources: Hetionet, Rhea

Order

BID increases the expression of SLC38A6ProteinHetionet hetionet:regulates:637-145389Inferred only
COX5B increases the expression of SLC38A6ProteinHetionet hetionet:regulates:1329-145389Inferred only
KEAP1 increases the expression of SLC38A6ProteinHetionet hetionet:regulates:9817-145389Inferred only
LRSAM1 increases the expression of SLC38A6ProteinHetionet hetionet:regulates:90678-145389Inferred only
PGAM1 increases the expression of SLC38A6ProteinHetionet hetionet:regulates:5223-145389Inferred only
PPP3R1 increases the expression of SLC38A6ProteinHetionet hetionet:regulates:5534-145389Inferred only
PSMD2 increases the expression of SLC38A6ProteinHetionet hetionet:regulates:5708-145389Inferred only
TFEB increases the expression of SLC38A6ProteinHetionet hetionet:regulates:7942-145389Inferred only
L-glutamate(1-) is transported by SLC38A6CompoundRhea RHEA:66336Inferred only
L-glutamine is transported by SLC38A6CompoundRhea RHEA:73419Inferred only

Reactions

2 reactions

L-glutamate(1-)L-glutamate(1-)
Transported by KCNK1 or BEST1 or KCNK2 or SLC25A14 or VDAC1 or LRRC8A or SLC38A6 or SLC17A8 or BEST2 or PANX1 or TTYH2 or TTYH3 and 5 more alternatives
Reaction pageReversibleBalanced
Rhea RHEA:66336CC BY 4.0Reference data

Other names

5 names

Resolves to: SLC38A6

Also called: Amino acid transporter SLC38A6N-system amino acid transporter 1NAT-1NAT1SNAT6

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