Proteins/UNIPROT:Q9UIF7

MUTYH

ProteinUNIPROT:Q9UIF7

Involved in oxidative DNA damage repair. Initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone. Possesses both adenine and 2-OH-A DNA glycosylase activities..

Function from UniProtKB (Q9UIF7), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

1 row

familial adenomatous polyposis 2 has a germline basis in MUTYHDiseaseGenCC HGNC:7527|MONDO:0012041Inferred only

Statements

27 statements

27 statements · 4 reference databases · Subject: MUTYH · Sources: gene ontology, Hetionet, UniProt, WikiPathways

Order

MDC1 covaries with MUTYHProteinHetionet hetionet:covaries:4595-9656Inferred only
RAET1E covaries with MUTYHProteinHetionet hetionet:covaries:135250-4595Inferred only
SIRPB2 covaries with MUTYHProteinHetionet hetionet:covaries:284759-4595Inferred only
TAS2R13 covaries with MUTYHProteinHetionet hetionet:covaries:4595-50838Inferred only
TNFSF9 covaries with MUTYHProteinHetionet hetionet:covaries:4595-8744Inferred only
APEX1 interacts with MUTYHProteinHetionet hetionet:interacts:328-4595Inferred only
MUTYH interacts with LRSAM1ProteinHetionet hetionet:interacts:4595-90678Inferred only
MUTYH interacts with MMS19ProteinHetionet hetionet:interacts:4595-64210Inferred only
MSH2 interacts with MUTYHProteinHetionet hetionet:interacts:4436-4595Inferred only
MSH6 interacts with MUTYHProteinHetionet hetionet:interacts:2956-4595Inferred only
MUTYH interacts with PCNAProteinHetionet hetionet:interacts:4595-5111Inferred only
MUTYH interacts with POLLProteinHetionet hetionet:interacts:27343-4595Inferred only

Show the remaining 15

MUTYH interacts with RPA1ProteinHetionet hetionet:interacts:4595-6117Inferred only
MUTYH interacts with RPA4ProteinHetionet hetionet:interacts:29935-4595Inferred only
MUTYH interacts with UBCProteinHetionet hetionet:interacts:4595-7316Inferred only
MUTYH participates in Base excision repairPathwayWikiPathways WP4752Inferred only
MUTYH participates in Genes and complexes involved in the DNA repair pathwaysPathwayWikiPathways WP4946Inferred only
MUTYH regulates negative regulation of necroptotic processBiological processgene ontology Q9UIF7|GO:0060546Inferred only
CCNC increases the expression of MUTYHProteinHetionet hetionet:regulates:892-4595Inferred only
FHL2 increases the expression of MUTYHProteinHetionet hetionet:regulates:2274-4595Inferred only
GBP2 increases the expression of MUTYHProteinHetionet hetionet:regulates:2634-4595Inferred only
HADH increases the expression of MUTYHProteinHetionet hetionet:regulates:3033-4595Inferred only
PARN increases the expression of MUTYHProteinHetionet hetionet:regulates:5073-4595Inferred only
PFDN2 increases the expression of MUTYHProteinHetionet hetionet:regulates:5202-4595Inferred only
PPAT increases the expression of MUTYHProteinHetionet hetionet:regulates:5471-4595Inferred only
STIL increases the expression of MUTYHProteinHetionet hetionet:regulates:6491-4595Inferred only
MUTYH requires the cofactor tetra-mu3-sulfido-tetraironCompoundUniProt Q9UIF7Inferred only

Other names

3 names

Resolves to: MUTYH

Also called: hMYHMutY homologMYH

← Every protein Find it in the graph →