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Proteins/UNIPROT:O15151
Contributes to p53/TP53 regulation. Inhibits p53/TP53- and p73/TP73-mediated cell cycle arrest and apoptosis by binding their transcriptional activation domains. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions..
Function from UniProtKB (O15151), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
2 rows
89 statements
89 statements · 4 reference databases · Subject: MDM4 · Sources: gene ontology, Hetionet, Reactome, WikiPathways
5 names
Resolves to: MDM4