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Proteins/UNIPROT:P51965
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes the covalent attachment of ISG15 to other proteins. Mediates the selective degradation of short-lived and abnormal proteins. In vitro also catalyzes 'Lys-48'-linked polyubiquitination. Catalyzes monoubiquitination of other proteins in both an E3-dependent and E3-independent manner..
Function from UniProtKB (P51965), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
182 statements
182 statements · 4 reference databases · Subject: UBE2E1 · Sources: gene ontology, Hetionet, Reactome, WikiPathways
1 reaction
5 names
Resolves to: UBE2E1
Reaction pageLeft to rightBalance undeterminableEC 2.3.2.23, 2.3.2.27, 6.2.1.45cytosol
Human-GEM MAR09491CC BY 4.0Reference data