1,2-dioctanoyl-sn-glycero-3-phosphocholine

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

209 compounds within 3 steps: 4 in 1, 9 in 2, 196 in 3

Three steps

iodideReach from here →
1. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
2. transport of chloride and choline (cytosol to extracellular)
3. transport of chloride and iodide (cytosol to extracellular)
Catalysed by ENPP2, SLC5A7, SLC26A4extracellular space, cytosolOne of 23 routes
L-valineReach from here →
1. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
2. transport of chloride and choline (cytosol to extracellular)
3. transport of chloride and valine (cytosol to extracellular)
Catalysed by ENPP2, SLC5A7, SLC6A14extracellular space, cytosolOne of 2 routes
CHEBI:16436Reach from here →
1. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
2. ATP:choline phosphotransferase
3. CTP:choline-phosphate cytidylyltransferase
Catalysed by ENPP2, CHKA, CHKB, PCYT1A and 1 morecytosol
oxaloacetateReach from here →
1. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
2. Acetyl-CoA:choline O-acetyltransferase
3. ATP citrate lyase (citrate)
Catalysed by ENPP2, CHAT, ACLYcytosol
L-arginineReach from here →
1. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
2. transport of chloride and choline (cytosol to extracellular)
3. transport of arginine and chloride (cytosol to extracellular)
Catalysed by ENPP2, SLC5A7, SLC6A14extracellular space, cytosolOne of 2 routes
nitric oxideReach from here →
1. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
2. choline + A = betaine aldehyde + AH2
3. 2 nitrite + AH2 + 2 H(+) = 2 nitric oxide + A + 2 H2O
Catalysed by ENPP2, CHDH, SUOX
3'-deoxy-3',4'-didehydro-CTPReach from here →
1. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
2. choline + A = betaine aldehyde + AH2
3. CTP + AH2 + S-adenosyl-L-methionine = 3'-deoxy-3',4'-didehydro-CTP + 5'-deoxyadenosine + L-methionine + A + H2O + H(+)
Catalysed by ENPP2, CHDH, RSAD2
(S)-2-hydroxyglutarateReach from here →
1. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
2. choline + A = betaine aldehyde + AH2
3. (S)-2-hydroxyglutarate + A = 2-oxoglutarate + AH2
Catalysed by ENPP2, CHDH, L2HGDH
CHEBI:16856Reach from here →
1. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
2. Acetyl-CoA:choline O-acetyltransferase
3. transport of acetylcholine and GSH (cytosol to extracellular)
Catalysed by ENPP2, CHAT, SLCO1A2, SLCO1B3cytosol, extracellular spaceOne of 2 routes
CHEBI:16857Reach from here →
1. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
2. transport of chloride and choline (cytosol to extracellular)
3. Transport of L-Threonine by Atb0 Transporter
Catalysed by ENPP2, SLC5A7, SLC6A14extracellular space, cytosol
oxalic acidReach from here →
1. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
2. transport of chloride and choline (cytosol to extracellular)
3. transport of chloride and oxalate (cytosol to extracellular)
Catalysed by ENPP2, SLC5A7, SLC26A6extracellular space, cytosol
L-isoleucineReach from here →
1. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
2. transport of chloride and choline (cytosol to extracellular)
3. transport of chloride and isoleucine (cytosol to extracellular)
Catalysed by ENPP2, SLC5A7, SLC6A14extracellular space, cytosolOne of 2 routes
CHEBI:17203Reach from here →
1. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
2. transport of chloride and choline (cytosol to extracellular)
3. Transport of L-Proline by the Apical Imino Amino Acid Transporters
Catalysed by ENPP2, SLC5A7, CLTRN, SLC6A20extracellular space, cytosolOne of 2 routes
anilineReach from here →
1. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
2. Acetyl-CoA:choline O-acetyltransferase
3. Acetyl-CoA:arylamine N-acetyltransferase
Catalysed by ENPP2, CHAT, NAT2, NAT1cytosol
CHEBI:17312Reach from here →
1. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
2. Acetyl-CoA:choline O-acetyltransferase
3. N1,N12-diacetylspermine to N1-acetylspermine conversion
Catalysed by ENPP2, CHATcytosolOne of 2 routes
5'-deoxyadenosineReach from here →
1. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
2. choline + A = betaine aldehyde + AH2
3. N(6)-dimethylallyladenosine(37) in tRNA + (sulfur carrier)-SH + AH2 + 2 S-adenosyl-L-methionine = 2-methylsulfanyl-N(6)-dimethylallyladenosine(37) in tRNA + (sulfur carrier)-H + 5'-deoxyadenosine + L-methionine + A + S-adenosyl-L-homocysteine + 2 H(+)
Catalysed by ENPP2, CHDH, CDK5RAP1One of 4 routes
L-cysteineReach from here →
1. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
2. Acetyl-CoA:choline O-acetyltransferase
3. N-acetylglutamate synthase (N-acetyl-L-cysteine)
Catalysed by ENPP2, CHAT, NAGScytosol, mitochondrial matrixOne of 3 routes
3,3',5'-triiodo-L-thyronine sulfateReach from here →
1. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
2. choline + A = betaine aldehyde + AH2
3. 3,3',5'-triiodo-L-thyronine sulfate + iodide + A + H(+) = L-thyroxine sulfate + AH2
Catalysed by ENPP2, CHDH, DIO1
3,3'-diiodo-L-thyronineReach from here →
1. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
2. choline + A = betaine aldehyde + AH2
3. 3,3'-diiodo-L-thyronine + iodide + A + H(+) = 3,3',5-triiodo-L-thyronine + AH2
Catalysed by ENPP2, CHDH, DIO1, DIO3One of 2 routes
3,3'-diiodo-L-thyronine sulfateReach from here →
1. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
2. choline + A = betaine aldehyde + AH2
3. 3,3'-diiodo-L-thyronine sulfate + iodide + A + H(+) = 3,3',5-triiodo-L-thyronine sulfate + AH2
Catalysed by ENPP2, CHDH, DIO1One of 2 routes
(7Z,10Z,13Z)-hexadecatrienoyl-CoAReach from here →
1. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
2. Acetyl-CoA:choline O-acetyltransferase
3. Fatty Acid Beta Oxidation (C18:3->C16:3), Mitochondrial
Catalysed by ENPP2, CHAT, HADHA, ACADVL and 1 morecytosol, mitochondrial matrix
glycine betaineReach from here →
1. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
2. choline dehydrogenase (choline)
3. p-cumic alcohol:NAD+ oxidoreductase
Catalysed by ENPP2, CHDH, ALDH7A1cytosolOne of 7 routes
CHEBI:17895Reach from here →
1. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
2. transport of chloride and choline (cytosol to extracellular)
3. Transport of L-Tyrosine by Atb0 Transporter
Catalysed by ENPP2, SLC5A7, SLC6A14extracellular space, cytosolOne of 2 routes
CHEBI:17927Reach from here →
1. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
2. Acetyl-CoA:choline O-acetyltransferase
3. N1,N8-diacetylspermidine to N1-acetylspermidine conversion
Catalysed by ENPP2, CHATcytosol
CHEBI:18019Reach from here →
1. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
2. transport of chloride and choline (cytosol to extracellular)
3. transport of chloride and lysine (cytosol to extracellular)
Catalysed by ENPP2, SLC5A7, SLC6A14extracellular space, cytosol
L-glutamineReach from here →
1. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
2. transport of chloride and choline (cytosol to extracellular)
3. Transport of L-Glutamine by Atb0 Transporter
Catalysed by ENPP2, SLC5A7, SLC6A14extracellular space, cytosol
CHEBI:18095Reach from here →
1. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
2. transport of chloride and choline (cytosol to extracellular)
3. transport of trans-4-hydroxy-L-proline (cytosol to extracellular)
Catalysed by ENPP2, SLC5A7, CLTRN, SLC6A20extracellular space, cytosol
N-carbamoyl-beta-alanineReach from here →
1. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
2. transport of chloride and choline (cytosol to extracellular)
3. Transport of 3-Ureidopropionate
Catalysed by ENPP2, SLC5A7extracellular space, cytosolOne of 2 routes
3',5'-diiodo-L-thyronineReach from here →
1. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
2. choline + A = betaine aldehyde + AH2
3. 3',5'-diiodo-L-thyronine + iodide + A + H(+) = 3,3',5'-triiodo-L-thyronine + AH2
Catalysed by ENPP2, CHDH, DIO3
(5Z)-dodecenoyl-CoAReach from here →
1. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
2. Acetyl-CoA:choline O-acetyltransferase
3. acetyl-CoA C-acyltransferase (3-oxomyrist-7-enoyl-CoA)
Catalysed by ENPP2, CHAT, HADHA, ACAA2 and 1 morecytosol, mitochondrial matrixOne of 2 routes
3-iodothyronamineReach from here →
1. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
2. choline + A = betaine aldehyde + AH2
3. 3-iodothyronamine + iodide + A + H(+) = 3,5-diiodothyronamine + AH2
Catalysed by ENPP2, CHDH, DIO1, DIO3One of 2 routes
(11Z)-docosenoyl-CoA(4-)Reach from here →
1. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
2. Acetyl-CoA:choline O-acetyltransferase
3. long-chain-fatty-acid-CoA ligase (cis-cetoleic acid)
Catalysed by ENPP2, CHAT, SLC27A2, ACSL4 and 6 morecytosolOne of 5 routes
3-iodo-L-thyronineReach from here →
1. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
2. choline + A = betaine aldehyde + AH2
3. 3-iodo-L-thyronine + iodide + A + H(+) = 3,5-diiodo-L-thyronine + AH2
Catalysed by ENPP2, CHDH, DIO1, DIO3One of 2 routes
(7Z)-tetradecenoyl-CoAReach from here →
1. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
2. Acetyl-CoA:choline O-acetyltransferase
3. long-chain-fatty-acid-CoA ligase ((7Z)-tetradecenoic acid)
Catalysed by ENPP2, CHAT, SLC27A2, ACSL4 and 6 morecytosolOne of 8 routes
3'-iodo-L-thyronineReach from here →
1. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
2. choline + A = betaine aldehyde + AH2
3. 3'-iodo-L-thyronine + iodide + A + H(+) = 3',5'-diiodo-L-thyronine + AH2
Catalysed by ENPP2, CHDH, DIO1, DIO2One of 2 routes
L-thyronineReach from here →
1. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
2. choline + A = betaine aldehyde + AH2
3. L-thyronine + iodide + A + H(+) = 3-iodo-L-thyronine + AH2
Catalysed by ENPP2, CHDH, DIO3
thyronamineReach from here →
1. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
2. choline + A = betaine aldehyde + AH2
3. thyronamine + iodide + A + H(+) = 3-iodothyronamine + AH2
Catalysed by ENPP2, CHDH, DIO3
3'-iodothyronamineReach from here →
1. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
2. choline + A = betaine aldehyde + AH2
3. 3'-iodothyronamine + iodide + A + H(+) = 3',5'-diiodothyronamine + AH2
Catalysed by ENPP2, CHDH, DIO1, DIO2One of 2 routes
3,3'-diiodothyronamineReach from here →
1. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
2. choline + A = betaine aldehyde + AH2
3. 3,3'-diiodothyronamine + iodide + A + H(+) = 3,3',5'-triiodothyronamine + AH2
Catalysed by ENPP2, CHDH, DIO1, DIO2One of 2 routes
3',5'-diiodothyronamineReach from here →
1. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
2. choline + A = betaine aldehyde + AH2
3. 3',5'-diiodothyronamine + iodide + A + H(+) = 3,3',5'-triiodothyronamine + AH2
Catalysed by ENPP2, CHDH, DIO3
3,3',5'-triiodothyronamineReach from here →
1. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
2. choline + A = betaine aldehyde + AH2
3. 3,3',5'-triiodothyronamine + iodide + A + H(+) = 3,3',5,5'-tetraiodothyronamine + AH2
Catalysed by ENPP2, CHDH, DIO3
(4Z,7Z,10Z,13Z)-hexadecatetraenoyl-CoAReach from here →
1. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
2. Acetyl-CoA:choline O-acetyltransferase
3. Fatty Acid Beta Oxidation (C18:4->C16:4), Mitochondrial
Catalysed by ENPP2, CHAT, HADHA, ACADVL and 1 morecytosol, mitochondrial matrixOne of 3 routes
(7Z,10Z)-hexadecadienoyl-CoAReach from here →
1. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
2. Acetyl-CoA:choline O-acetyltransferase
3. Fatty Acid Beta Oxidation Trans (C18:2->C16:2), Mitochondrial
Catalysed by ENPP2, CHAT, HADHA, ACADVL and 1 morecytosol, mitochondrial matrix
(4Z,7Z)-decadienoyl-CoAReach from here →
1. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
2. Acetyl-CoA:choline O-acetyltransferase
3. Fatty Acid Beta Oxidation (C12:3->C10:2), Mitochondrial
Catalysed by ENPP2, CHAT, ECHS1, ACAA2 and 1 morecytosol, mitochondrial matrixOne of 2 routes
(5Z)-octenoyl-CoAReach from here →
1. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
2. Acetyl-CoA:choline O-acetyltransferase
3. Fatty Acid Beta Oxidation (C10:2->C8:1), Mitochondrial
Catalysed by ENPP2, CHAT, ECHS1, ACAA2 and 1 morecytosol, mitochondrial matrixOne of 2 routes
CHEBI:240943Reach from here →
1. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
2. transport of chloride and choline (cytosol to extracellular)
3. 2-Methylbutyrylglycine Transport, Extracellular
Catalysed by ENPP2, SLC5A7, SLC6A5extracellular space, cytosolOne of 2 routes
hypochlorous acidReach from here →
1. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
2. transport of chloride and choline (cytosol to extracellular)
3. Peroxidase
Catalysed by ENPP2, SLC5A7, LPOextracellular space, cytosolOne of 4 routes
potassium atomReach from here →
1. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
2. transport of chloride and choline (cytosol to extracellular)
3. transport of chloride (cytosol to extracellular)
Catalysed by ENPP2, SLC5A7, SLC12A2, SLC12A1extracellular space, cytosolOne of 2 routes
CHEBI:27540Reach from here →
1. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
2. Acetyl-CoA:choline O-acetyltransferase
3. medium-chain acyl-CoA ligase (hexanoic acid)
Catalysed by ENPP2, CHAT, ACSM4, ACSM1 and 4 morecytosolOne of 6 routes
elaidic acidReach from here →
1. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
2. Acetyl-CoA:choline O-acetyltransferase
3. long-chain-fatty-acid-CoA ligase (elaidate)
Catalysed by ENPP2, CHAT, SLC27A2, ACSL4 and 6 morecytosolOne of 5 routes