Compound

3-iodo-L-thyronine

Major microspecies at pH 7.3.

Definition from ChEBI (CHEBI:232627), read 2026-09-23. CC BY 4.0.

CHEBI:232627ChEBI

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Structure

2D depiction · 3D model shown

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A generated conformer of 3-iodo-L-thyronine — one low-energy arrangement PubChem computed, not a measured structure. Hydrogens are not drawn; the formula counts them.

Class: Organic compound
Formula: C15H14INO4
Mass: 399.184 g/mol
Charge: 0
InChIKey: SXQVOFSDWXYIRP-ZDUSSCGKSA-N
SMILES: [NH3+][C@@H](Cc1ccc(Oc2ccc(O)cc2)c(I)c1)C(=O)[O-]
Look it up: ChEBI PubChem By InChIKey

Identity from ChEBI, geometry from PubChem. Not evidence.

What it touches on the way

Mechanistic reach

2 entities

2 entities reached.

0 reported hops2 assembled from the scaffold

What the reference databases state

Chemical structure

3-iodo-L-thyronine has the functional parent 3,5-diiodo-L-thyronineCompoundChEBI CHEBI:232627Inferred only

Statements

1 statement

1 statement · 1 reference database · Subject: 3-iodo-L-thyronine · Sources: Rhea

Order

3-iodo-L-thyronine is a substrate of DIO3ProteinRhea RHEA:83771Inferred only

Reactions

3 reactions

3-iodo-L-thyronine+iodide+A+hydron3,5-diiodo-L-thyronine+AH2
Catalysed by DIO1 or DIO3
Reaction pageRight to leftBalanced
Rhea RHEA:82895CC BY 4.0Reference data
L-thyronine+iodide+A+hydron3-iodo-L-thyronine+AH2
Catalysed by DIO3
Reaction pageRight to leftBalanced
Rhea RHEA:83771CC BY 4.0Reference data
3-iodo-L-thyronine+iodide+A+hydron3,3'-diiodo-L-thyronine+AH2
Catalysed by DIO1
Reaction pageRight to leftBalanced
Rhea RHEA:83783CC BY 4.0Reference data

Other names

2 names

Resolves to: 3-iodo-L-thyronine

Also called: 3-monoiodo-L-thyronine zwitterion3-T1