3',5'-diiodo-L-thyronine

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

158 compounds within 3 steps: 3 in 1, 15 in 2, 140 in 3

One step

AReach from here →
1. 3'-iodo-L-thyronine + iodide + A + H(+) = 3',5'-diiodo-L-thyronine + AH2
Catalysed by DIO1, DIO2
iodideReach from here →
1. 3'-iodo-L-thyronine + iodide + A + H(+) = 3',5'-diiodo-L-thyronine + AH2
Catalysed by DIO1, DIO2
3'-iodo-L-thyronineReach from here →
1. 3'-iodo-L-thyronine + iodide + A + H(+) = 3',5'-diiodo-L-thyronine + AH2
Catalysed by DIO1, DIO2

Two steps

Three steps

Catalysed by DIO1, DIO2, KDM1A, KDM1BOne of 3 routes

all-trans-retinolReach from here →

Catalysed by DIO1, DIO2, RETSAT

AH2Reach from here →

Catalysed by DIO1, DIO2, AIFM1, PYROXD1One of 19 routes

L-cysteineReach from here →

Catalysed by DIO1, DIO2, MOCOS

diiodineReach from here →

Catalysed by DIO1, DIO2, TPOcytosolOne of 2 routes

hypoioditeReach from here →

Catalysed by DIO1, DIO2, MPO, LPO

chlorine(.)Reach from here →

Catalysed by DIO1, DIO2, SLC26A4extracellular space, cytosol

3,3',5-triiodo-L-thyronineReach from here →

Catalysed by DIO1, DIO2, DIO3cytosolOne of 4 routes

7,8-dihydrofolateReach from here →

Catalysed by DIO1, DIO2, MTO1

L-thyroxineReach from here →

Catalysed by DIO1, DIO2cytosolOne of 2 routes

a 2,3-dehydroacyl-CoAReach from here →

Catalysed by DIO1, DIO2, ACAD10

Fe(II)-heme aReach from here →

Catalysed by DIO1, DIO2, COX15

Mo-molybdopterinReach from here →

Catalysed by DIO1, DIO2, MOCOS

Catalysed by DIO1, DIO2, MOCOS, NAGS

mitochondrial matrix

One of 3 routes

(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphateReach from here →

Catalysed by DIO1, DIO2, AIFM1, PYROXD1 and 1 more

(18S)-hydroxy-(5Z,8Z,11Z,14Z,16E)-eicosapentaenoateReach from here →

Catalysed by DIO1, DIO2, AIFM1, PYROXD1 and 1 more

(15S)-hydroxy-(5Z,8Z,11Z,13E,17Z)-eicosapentaenoateReach from here →

Catalysed by DIO1, DIO2, AIFM1, PYROXD1 and 1 more

all-trans-3,4-didehydroretinolReach from here →

Catalysed by DIO1, DIO2, RETSAT, CYP27C1

all-trans-4-hydroxyretinolReach from here →

Catalysed by DIO1, DIO2, RETSAT, CYP27C1

prostaglandin H3Reach from here →

Catalysed by DIO1, DIO2, AIFM1, PYROXD1 and 1 more

13-hydroxy-(9Z,11E)-octadecadienoateReach from here →

Catalysed by DIO1, DIO2, AIFM1, PYROXD1 and 1 more

9-hydroxy-(10E,12Z)-octadecadienoateReach from here →

Catalysed by DIO1, DIO2, AIFM1, PYROXD1 and 1 more

2,4-dinitrophenyl-S-glutathioneReach from here →

Catalysed by DIO1, DIO2, DIO3, SLCO1A2 and 1 morecytosol, extracellular spaceOne of 4 routes

(13R)-hydroxy-(9Z,11E)-octadecadienoateReach from here →

Catalysed by DIO1, DIO2, AIFM1, PYROXD1 and 2 more

2-[(11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoyl]-sn-glycero-3-phosphocholineReach from here →

Catalysed by DIO1, DIO2, AIFM1, PYROXD1 and 1 more

2-[(15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-sn-glycero-3-phosphocholineReach from here →

Catalysed by DIO1, DIO2, AIFM1, PYROXD1 and 1 more

2-[(15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-sn-glycero-3-phosphocholineReach from here →

Catalysed by DIO1, DIO2, AIFM1, PYROXD1 and 1 more

2-(prostaglandin H2)-sn-glycero-3-phosphoethanolamineReach from here →

Catalysed by DIO1, DIO2, AIFM1, PYROXD1 and 1 more

2-(prostaglandin H2)-sn-glycero-3-phosphocholineReach from here →

Catalysed by DIO1, DIO2, AIFM1, PYROXD1 and 1 more

all-trans-retinyl tetradecanoateReach from here →

Catalysed by DIO1, DIO2, RETSAT, AWAT2

cholineReach from here →

Catalysed by DIO1, DIO2, SLC26A4, SLC5A7extracellular space, cytosol

pyruvateReach from here →

Catalysed by DIO1, DIO2, MOCOS, CTHcytosolOne of 6 routes

(S)-malateReach from here →

Catalysed by DIO1, DIO2, D2HGDHmitochondrial matrix, cytosolOne of 5 routes

L-leucineReach from here →

Catalysed by DIO1, DIO2, MOCOS, SLC7A9 and 1 moreextracellular space, cytosolOne of 5 routes

all-trans-3-hydroxyretinolReach from here →

Catalysed by DIO1, DIO2, RETSAT, CYP27C1

CHEBI:15699Reach from here →

Catalysed by DIO1, DIO2, MOCOS, SLC7A5extracellular space, cytosolOne of 3 routes

formateReach from here →

Catalysed by DIO1, DIO2, KDM1A, KDM1B and 1 more

CHEBI:15971Reach from here →

Catalysed by DIO1, DIO2, MOCOS, SLC7A6extracellular space, cytosolOne of 3 routes

methanethiolReach from here →

Catalysed by DIO1, DIO2, KDM1A, KDM1B and 1 more

sulfateReach from here →

Catalysed by DIO1, DIO2, SLC26A4, SLC26A6extracellular space, cytosol

L-cystineReach from here →

Catalysed by DIO1, DIO2, MOCOS, TXNRD1 and 2 morecytosolOne of 4 routes

11-cis-retinolReach from here →

Catalysed by DIO1, DIO2, RETSATcytosolOne of 2 routes

cob(II)alaminReach from here →

Catalysed by DIO1, DIO2, AIFM1, PYROXD1 and 1 more

L-citrullineReach from here →

Catalysed by DIO1, DIO2, MOCOS, SLC7A6extracellular space, cytosolOne of 2 routes