a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate)

1. a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate)(out) + cholesterol(in) = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate)(in) + cholesterol(out)

Catalysed by OSBPinner side of the membrane, outer side of the membraneOne of 2 routes

1. ATP:1-Phosphatidyl-1D-myo-inositol 4-phosphotransferase

Catalysed by PTPRQ, INPPL1, CTDSPL2, PMPCA and 9 morecytosolOne of 2 routes

1. phosphoinositide phospholipase C (1-phosphatidyl-1D-myo-inositol-4-phosphate)

Catalysed by PLCH2, PLCG2, PLCG1, PLCD1 and 10 morecytosolOne of 2 routes

1. a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate)(out) + a 1,2-diacyl-sn-glycero-3-phospho-L-serine(in) = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate)(in) + a 1,2-diacyl-sn-glycero-3-phospho-L-serine(out)

Catalysed by OSBPL9, OSBPL11, OSBPL10, OSBPL8 and 2 moreinner side of the membrane, outer side of the membraneOne of 2 routes

1. a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate)(out) + a 1,2-diacyl-sn-glycero-3-phosphocholine(in) = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate)(in) + a 1,2-diacyl-sn-glycero-3-phosphocholine(out)

Catalysed by OSBPL3inner side of the membrane, outer side of the membraneOne of 2 routes

1. a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate

Catalysed by SYNJ2, SYNJ1, SACM1L, INPP5F

1. a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ADP + H(+)

Catalysed by PIP5K1B, PIP5K1C, PIP5K1A

1. phosphoinositide phospholipase C (1-phosphatidyl-1D-myo-inositol-4-phosphate)
2. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase

Catalysed by PLCH2, PLCG2, PLCG1, PLCD1 and 15 morecytosol

1. a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate)(out) + cholesterol(in) = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate)(in) + cholesterol(out)
2. cholesterol + AH2 + O2 = 25-hydroxycholesterol + A + H2O

Catalysed by OSBP, CH25Hinner side of the membrane, outer side of the membrane