Loading the page.
Proteins/UNIPROT:Q96SU4
Interacts with OSBPL11 to function as lipid transfer proteins. Together they form a heterodimer that localizes at the ER-trans-Golgi membrane contact sites, and exchanges phosphatidylserine (1,2-diacyl-sn-glycero-3-phospho-L-serine, PS) for phosphatidylinositol-4-phosphate (1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate), PI(4)P) between the two organelles, a step that is critical for sphingomyelin synthesis in the Golgi complex. Interacts with OSBPL10 to function as lipid transfer proteins. Together they form a heterodimer that localizes at the ER-trans-Golgi membrane contact sites, and exchanges phosphatidylserine (1,2-diacyl-sn-glycero-3-phospho-L-serine, PS) for phosphatidylinositol-4-phosphate (1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate), PI(4)P) between the two organelles, a step that is critical for sphingomyelin synthesis in the Golgi complex..
Function from UniProtKB (Q96SU4), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
115 statements
115 statements · 5 reference databases · Subject: OSBPL9 · Sources: Bgee, Hetionet, Human Protein Atlas, Reactome, Rhea
1 reaction
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate)+a 1,2-diacyl-sn-glycero-3-phospho-L-serinea 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate)+a 1,2-diacyl-sn-glycero-3-phospho-L-serine
Transported by OSBPL9 or OSBPL11 or OSBPL10 or OSBPL8 or OSBPL6 or OSBPL5
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:81667CC BY 4.0Reference data
4 names
Resolves to: OSBPL9