Compound

a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate)

The trianion of a 1-phosphatidyl-1D-myo-inositol 3-phosphate; major species at pH 7.3.

Definition from ChEBI (CHEBI:58088), read 2026-09-23. CC BY 4.0.

CHEBI:58088ChEBI

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Structure

2D depiction

Class: Structural class, not a single molecule
Formula: C11H15O16P2R2
Mass: 465.175 g/mol
Charge: -3
SMILES: *C(=O)OC[C@]([H])(COP(=O)([O-])O[C@@H]1[C@H](O)[C@H](OP(=O)([O-])[O-])[C@@H](O)[C@H](O)[C@H]1O)OC(*)=O
Look it up: ChEBI

Identity from ChEBI. Not evidence.

What it touches on the way

Mechanistic reach

21 entities

21 entities reached.

0 reported hops21 assembled from the scaffold

Show the remaining 9

What the reference databases state

Statements

42 statements

42 statements · 2 reference databases · Subject: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) · Sources: Human-GEM, Rhea

Order

1-phosphatidyl-1D-myo-inositol is converted to a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate)CompoundHuman-GEM MAR06542Inferred only
1-phosphatidyl-1D-myo-inositol is converted to a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate)CompoundHuman-GEM MAR08829Inferred only
1-phosphatidyl-1D-myo-inositol is converted to a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate)CompoundHuman-GEM MAR08827Inferred only
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) is converted to 1-phosphatidyl-1D-myo-inositolCompoundHuman-GEM MAR06543Inferred only
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) is converted to 1-phosphatidyl-1D-myo-inositolCompoundHuman-GEM MAR08812Inferred only
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) is converted to a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)CompoundRhea RHEA:12316Inferred only
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) is converted to a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate)CompoundRhea RHEA:12709Inferred only
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) is a substrate of MTM1ProteinHuman-GEM MAR08812Inferred only
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) is a substrate of MTM1ProteinRhea RHEA:12316Inferred only
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) is a substrate of MTM1ProteinHuman-GEM MAR06543Inferred only
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) is a substrate of MTMR1ProteinRhea RHEA:12316Inferred only
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) is a substrate of MTMR12ProteinHuman-GEM MAR06543Inferred only

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a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) is a substrate of MTMR14ProteinRhea RHEA:12316Inferred only
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) is a substrate of MTMR2ProteinRhea RHEA:12316Inferred only
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) is a substrate of MTMR3ProteinRhea RHEA:12316Inferred only
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) is a substrate of MTMR4ProteinRhea RHEA:12316Inferred only
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) is a substrate of MTMR6ProteinRhea RHEA:12316Inferred only
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) is a substrate of MTMR7ProteinRhea RHEA:12316Inferred only
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) is a substrate of MTMR8ProteinRhea RHEA:12316Inferred only
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) is a substrate of PIKFYVEProteinHuman-GEM MAR06544Inferred only
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) is a substrate of PIKFYVEProteinRhea RHEA:13609Inferred only
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) is a substrate of PIP4K2AProteinHuman-GEM MAR03325Inferred only
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) is a substrate of PIP4K2BProteinHuman-GEM MAR03325Inferred only
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) is a substrate of PIP4K2CProteinHuman-GEM MAR03325Inferred only
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) is a substrate of PIP5K1AProteinHuman-GEM MAR08815Inferred only
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) is a substrate of PIP5K1AProteinHuman-GEM MAR03318Inferred only
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) is a substrate of PIP5K1AProteinHuman-GEM MAR08813Inferred only
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) is a substrate of PIP5K1AProteinHuman-GEM MAR08814Inferred only
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) is a substrate of PIP5K1BProteinHuman-GEM MAR08815Inferred only
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) is a substrate of PIP5K1BProteinHuman-GEM MAR08814Inferred only
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) is a substrate of PIP5K1BProteinHuman-GEM MAR08813Inferred only
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) is a substrate of PIP5K1BProteinHuman-GEM MAR03318Inferred only
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) is a substrate of PIP5K1CProteinHuman-GEM MAR03318Inferred only
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) is a substrate of PIP5K1CProteinHuman-GEM MAR08814Inferred only
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) is a substrate of PIP5K1CProteinHuman-GEM MAR08813Inferred only
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) is a substrate of PIP5K1CProteinHuman-GEM MAR08815Inferred only
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) is a substrate of PIP5KL1ProteinHuman-GEM MAR08813Inferred only
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) is a substrate of PIP5KL1ProteinHuman-GEM MAR08815Inferred only
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) is a substrate of PIP5KL1ProteinHuman-GEM MAR08814Inferred only
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) is a substrate of SACM1LProteinRhea RHEA:12316Inferred only
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) is a substrate of SYNJ1ProteinRhea RHEA:12316Inferred only
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) is a substrate of SYNJ2ProteinRhea RHEA:12316Inferred only

Reactions

23 reactions

a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate)+ATPADP+proton+MAM02735g
Catalysed by PIP5K1B or PIP5K1A or PIP5K1C
Reaction pageLeft to rightBalance undeterminableEC 2.7.1.68Golgi apparatus
Human-GEM MAR03318CC BY 4.0Reference data
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate)+ATPADP+proton+MAM02735n
Reaction pageLeft to rightBalance undeterminableEC 2.7.1.68nucleus
Human-GEM MAR03324CC BY 4.0Reference data
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate)+ATPADP+proton+MAM02735r
Catalysed by PIP4K2A or PIP4K2C or PIP4K2B
Reaction pageLeft to rightBalance undeterminableEC 2.7.1.68endoplasmic reticulum
Human-GEM MAR03325CC BY 4.0Reference data
ATP+1-phosphatidyl-1D-myo-inositola 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate)+ADP+proton
Catalysed by PIK3C3
Reaction pageLeft to rightBalance undeterminableEC 2.7.1.137cytosol
Human-GEM MAR06542CC BY 4.0Reference data
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate)+water1-phosphatidyl-1D-myo-inositol+phosphate(3-)
Catalysed by MTMR12 or MTM1
Reaction pageLeft to rightBalance undeterminableEC 3.1.3.64cytosol
Human-GEM MAR06543CC BY 4.0Reference data
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate)+ATPMAM00555c+ADP+proton
Catalysed by PIKFYVE
Reaction pageLeft to rightBalance undeterminableEC 2.7.1.150cytosol
Human-GEM MAR06544CC BY 4.0Reference data
MAM00555c+watera 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate)+phosphate(3-)
Catalysed by MTMR7 or MTMR1 or MTMR2 or MTMR8 or TNS2 or NT5DC3 or FIG4 or SGPP1 or CTDSPL2 or PTPRQ or MTMR6 or DUSP11 and 8 more alternatives
Reaction pageLeft to rightBalance undeterminableEC 3.1.3.-cytosol
Human-GEM MAR06545CC BY 4.0Reference data
MAM00551c+watera 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate)+phosphate(3-)
Catalysed by INPP4A or INPP4B
Reaction pageLeft to rightBalance undeterminableEC 3.1.3.66cytosol
Human-GEM MAR06549CC BY 4.0Reference data
MAM00551n+watera 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate)+phosphate(3-)
Catalysed by INPP4A or INPP4B
Reaction pageLeft to rightBalance undeterminableEC 3.1.3.66nucleus
Human-GEM MAR08810CC BY 4.0Reference data
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate)+water1-phosphatidyl-1D-myo-inositol+phosphate(3-)
Catalysed by MTM1
Reaction pageLeft to rightBalance undeterminableEC 3.1.3.64, 3.1.3.67nucleus
Human-GEM MAR08812CC BY 4.0Reference data
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate)+ATPMAM00551c+ADP+proton
Catalysed by PIP5K1B or PIP5K1A or PIP5KL1 or PIP5K1C
Reaction pageLeft to rightBalance undeterminableEC 2.7.1.68cytosol
Human-GEM MAR08813CC BY 4.0Reference data
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate)+ATPMAM00551n+ADP+proton
Catalysed by PIP5K1B or PIP5K1A or PIP5KL1 or PIP5K1C
Reaction pageLeft to rightBalance undeterminableEC 2.7.1.68nucleus
Human-GEM MAR08814CC BY 4.0Reference data

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Other names

3 names

Resolves to: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate)

Also called: 1,2-diacyl-sn-glycero-3-phospho-1D-myo-inositol-3-phosphatePIP[3]
Systematic name: 2,3-bis(alkanoxy)propyl (1S,2R,3S,4S,5R,6R)-2,3,4,6-tetrahydroxy-5-(phosphonatooxy)cyclohexyl phosphate