Loading the page.
Proteins/UNIPROT:Q9BXB4
Plays a role in regulating ADIPOQ and FABP4 levels in differentiating adipocytes and is also involved in regulation of adipocyte triglyceride storage. Weakly binds 25-hydroxycholesterol. Interacts with OSBPL9 to function as lipid transfer proteins. Together they form a heterodimer that localizes at the ER-trans-Golgi membrane contact sites, and exchanges phosphatidylserine (1,2-diacyl-sn-glycero-3-phospho-L-serine, PS) for phosphatidylinositol-4-phosphate (1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate), PI(4)P) between the two organelles, a step that is critical for sphingomyelin synthesis in the Golgi complex..
Function from UniProtKB (Q9BXB4), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
21 statements
21 statements · 4 reference databases · Subject: OSBPL11 · Sources: Bgee, Hetionet, Reactome, Rhea
1 reaction
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate)+a 1,2-diacyl-sn-glycero-3-phospho-L-serinea 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate)+a 1,2-diacyl-sn-glycero-3-phospho-L-serine
Transported by OSBPL9 or OSBPL11 or OSBPL10 or OSBPL8 or OSBPL6 or OSBPL5
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:81667CC BY 4.0Reference data
4 names
Resolves to: OSBPL11