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Proteins/UNIPROT:Q9Y6K8
Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Active on AMP and dAMP with ATP as a donor. When GTP is used as phosphate donor, the enzyme phosphorylates AMP, CMP, and to a small extent dCMP. Also displays broad nucleoside diphosphate kinase activity..
Function from UniProtKB (Q9Y6K8), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
52 statements
52 statements · 6 reference databases · Subject: AK5 · Sources: Bgee, Hetionet, Human Protein Atlas, Human-GEM, Reactome, Rhea
9 reactions
2 names
Resolves to: AK5
Reaction pageReversibleBalancedEC 2.7.4.3mitochondrial matrix
Human-GEM MAR04004CC BY 4.0Reference data
ADP+CHEBI:16174ATP+MAM01639c
Catalysed by AK2 or AK6 or AK1 or AK7 or AK3 or AK5 or AK9 or AK4 or AK8 or ACAD9
Reaction pageReversibleBalancedEC 2.7.4.11, 2.7.4.3cytosol
Human-GEM MAR04480CC BY 4.0Reference data
Catalysed by AK5
Reaction pageReversibleBalancedEC 2.7.4.3cytosol
Human-GEM MAR07800CC BY 4.0Reference data
2CHEBI:16174MAM01639c+CHEBI:16284
Catalysed by AK5
Reaction pageReversibleBalancedEC 2.7.4.3cytosol
Human-GEM MAR07802CC BY 4.0Reference data
Catalysed by AK5
Reaction pageReversibleBalancedEC 2.7.4.3cytosol
Human-GEM MAR08461CC BY 4.0Reference data
Catalysed by AK1 or AK4 or AK2 or AK9 or AK7 or AK8 or AK6 or AK5
Reaction pageDirection not assertedBalanced
Rhea RHEA:12973CC BY 4.0Reference data
a ribonucleoside 5'-diphosphate+ATP(4-)a ribonucleoside 5'-triphosphate+ADP(3-)
Catalysed by NME4 or NME6 or AK1 or NME1 or NME2 or AK4 or CMPK1 or NME3 or CMPK2 or AK9 or AK7 or AK8 and 1 more alternative
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:18113CC BY 4.0Reference data