Compound
phosphatidyl-L-serine
Derivatives of phosphatidic acids in which the phosphoric acid is bound in ester linkage to a serine moiety.
What it touches on the way
Mechanistic reach
10 entities
10 entities reached.
0 reported hops10 assembled from the scaffold
- PLD1ProteinUNIPROT:Q13393substrate ofInferred only132 paths44 endpoints
- ATP8A1ProteinUNIPROT:Q9Y2Q0transported byInferred only132 paths65 endpoints
- ABCA1ProteinUNIPROT:O95477transported byInferred only47 paths47 endpoints
- PLD2ProteinUNIPROT:O14939substrate ofInferred only31 paths31 endpoints
- PISDProteinUNIPROT:Q9UG56substrate ofInferred only26 paths13 endpoints
- PLIN2ProteinUNIPROT:Q99541substrate ofInferred only5 paths5 endpoints
- FITM2ProteinUNIPROT:Q8N6M3substrate ofInferred only3 paths3 endpoints
- BSCL2ProteinUNIPROT:Q96G97substrate ofInferred only3 paths3 endpoints
- PLIN1ProteinUNIPROT:O60240substrate ofInferred only2 paths2 endpoints
- PLIN3ProteinUNIPROT:O60664substrate ofInferred only2 paths2 endpoints
What the reference databases state
Statements
23 statements
23 statements · 1 reference database · Subject: phosphatidyl-L-serine · Sources: Human-GEM
- phosphatidyl-L-serine is converted to phosphatidic acidCompoundHuman-GEM MAR03791Inferred only
- phosphatidyl-L-serine is converted to phosphatidic acidCompoundHuman-GEM MAR00660Inferred only
- phosphatidyl-L-serine is converted to phosphatidic acidCompoundHuman-GEM MAR03798Inferred only
- phosphatidyl-L-serine is converted to phosphatidylethanolamineCompoundHuman-GEM MAR01658Inferred only
- phosphatidyl-L-serine is converted to phosphatidylethanolamineCompoundHuman-GEM MAR00627Inferred only
- phosphatidyl-L-serine is a substrate of BSCL2ProteinHuman-GEM MAR00031Inferred only
- phosphatidyl-L-serine is a substrate of FITM1ProteinHuman-GEM MAR00031Inferred only
- phosphatidyl-L-serine is a substrate of FITM2ProteinHuman-GEM MAR00031Inferred only
- phosphatidyl-L-serine is a substrate of PISDProteinHuman-GEM MAR00627Inferred only
- phosphatidyl-L-serine is a substrate of PISDProteinHuman-GEM MAR01658Inferred only
- phosphatidyl-L-serine is a substrate of PLD1ProteinHuman-GEM MAR00660Inferred only
- phosphatidyl-L-serine is a substrate of PLD1ProteinHuman-GEM MAR03791Inferred only
Show the remaining 11
- phosphatidyl-L-serine is a substrate of PLD1ProteinHuman-GEM MAR03798Inferred only
- phosphatidyl-L-serine is a substrate of PLD2ProteinHuman-GEM MAR00660Inferred only
- phosphatidyl-L-serine is a substrate of PLIN1ProteinHuman-GEM MAR00031Inferred only
- phosphatidyl-L-serine is a substrate of PLIN2ProteinHuman-GEM MAR00031Inferred only
- phosphatidyl-L-serine is a substrate of PLIN3ProteinHuman-GEM MAR00031Inferred only
- phosphatidyl-L-serine is a substrate of PLIN4ProteinHuman-GEM MAR00031Inferred only
- phosphatidyl-L-serine is transported by ABCA1ProteinHuman-GEM MAR09901Inferred only
- phosphatidyl-L-serine is transported by ATP10AProteinHuman-GEM MAR01664Inferred only
- phosphatidyl-L-serine is transported by ATP10AProteinHuman-GEM MAR01661Inferred only
- phosphatidyl-L-serine is transported by ATP8A1ProteinHuman-GEM MAR01661Inferred only
- phosphatidyl-L-serine is transported by ATP8A1ProteinHuman-GEM MAR01664Inferred only
Reactions
25 reactions
0.19a 1,2-diacyl-sn-glycerol+0.0014MAM00511c+0.0024a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine+0.00061-O-acyl-sn-glycero-3-phosphocholine(1+)+0.005CHEBI:1307929+0.34a cholesterol ester+0.00081-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphoethanolamine+0.00921,2-diacyl-sn-glycero-3-phosphocholine(1+)+0.0034phosphatidylethanolamine+0.00161-phosphatidyl-1D-myo-inositol+0.0002phosphatidyl-L-serine+0.0004a sphingomyelin+0.44a triacylglycerol+0.005fatty acidMAM02392c
Catalysed by PLIN3 or FITM1 or PLIN2 or PLIN1 or PLIN4 or BSCL2 or FITM2
Reaction pageLeft to rightBalance undeterminableGO:0005829
Human-GEM MAR00031CC BY 4.0Reference data
phosphatidyl-L-serinephosphatidyl-L-serine
Reaction pageReversibleBalance undeterminableGO:0005829, GO:0005783
Human-GEM MAR00466CC BY 4.0Reference data
carbon dioxide+MAM02697cproton+phosphatidyl-L-serine
Catalysed by PISD
Reaction pageLeft to rightBalance undeterminableEC 4.1.1.65GO:0005829
Human-GEM MAR00616CC BY 4.0Reference data
phosphatidylethanolamine+L-seryl residueethanolamine+phosphatidyl-L-serine
Catalysed by PTDSS2
Reaction pageLeft to rightBalance undeterminableEC 2.7.8.29GO:0005829
Human-GEM MAR00622CC BY 4.0Reference data
1,2-diacyl-sn-glycero-3-phosphocholine(1+)+L-seryl residuecholine+phosphatidyl-L-serine
Catalysed by PTDSS1
Reaction pageLeft to rightBalance undeterminableEC 2.7.8.29GO:0005829
Human-GEM MAR00623CC BY 4.0Reference data
proton+phosphatidyl-L-serinecarbon dioxide+phosphatidylethanolamine
Catalysed by PISD
Reaction pageLeft to rightBalance undeterminableEC 4.1.1.65GO:0005829
Human-GEM MAR00627CC BY 4.0Reference data
water+phosphatidyl-L-serineproton+phosphatidic acid+L-seryl residue
Reaction pageLeft to rightBalance undeterminableEC 3.1.4.4GO:0005829
Human-GEM MAR00660CC BY 4.0Reference data
Reaction pageReversibleBalance undeterminableGO:0005615
Human-GEM MAR00661CC BY 4.0Reference data
phosphatidyl-L-serinephosphatidyl-L-serine
Reaction pageReversibleBalance undeterminableGO:0005829, GO:0005794
Human-GEM MAR01657CC BY 4.0Reference data
proton+phosphatidyl-L-serinecarbon dioxide+phosphatidylethanolamine
Catalysed by PISD
Reaction pageLeft to rightBalance undeterminableEC 4.1.1.65GO:0005759
Human-GEM MAR01658CC BY 4.0Reference data
ATP+water+phosphatidyl-L-serineADP+proton+phosphate(3-)+phosphatidyl-L-serine
Transported by ATP8A1 or ATP10A
Reaction pageLeft to rightBalance undeterminableGO:0005829, GO:0005615
Human-GEM MAR01661CC BY 4.0Reference data
ATP+water+phosphatidyl-L-serineADP+proton+phosphate(3-)+phosphatidyl-L-serine
Transported by ATP8A1 or ATP10A
Reaction pageLeft to rightBalance undeterminableGO:0005829, GO:0005759
Human-GEM MAR01664CC BY 4.0Reference data
Where it reaches
10 systems, 21 regions, 65 tissues, 65 transporter routes — routes, not measurements: transporters known to carry phosphatidyl-L-serine are expressed there, and no source reports it arriving.
Loading the model…
Other names
4 names
Resolves to: phosphatidyl-L-serine
- Also called
- phosphatidyl-L-serinesPhosphatidylserinePSPtd-L-Ser