Loading the page.
Proteins/UNIPROT:Q9H2U2
Hydrolyzes inorganic pyrophosphate. This activity is essential for correct regulation of mitochondrial membrane potential, and mitochondrial organization and function..
Function from UniProtKB (Q9H2U2), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
3 rows
52 statements
52 statements · 5 reference databases · Subject: PPA2 · Sources: gene ontology, Hetionet, Reactome, UniProt, WikiPathways
6 reactions
water+diphosphate(3-)proton+2phosphate(3-)
Catalysed by LHPP or PPA2 or PRUNE1 or PPA1
Reaction pageLeft to rightBalancedEC 3.6.1.1endoplasmic reticulum
Human-GEM MAR03975CC BY 4.0Reference data
water+diphosphate(3-)proton+2phosphate(3-)
Catalysed by
3 names
Resolves to: PPA2
Reaction pageLeft to rightBalancedEC 3.6.1.1cytosol
Human-GEM MAR03977CC BY 4.0Reference data
water+diphosphate(3-)proton+2phosphate(3-)
Catalysed by LHPP or PPA2 or PRUNE1 or PPA1
Reaction pageLeft to rightBalancedEC 3.6.1.1peroxisome
Human-GEM MAR03979CC BY 4.0Reference data
water+diphosphate(3-)proton+2phosphate(3-)
Catalysed by LHPP or PPA2 or PRUNE1 or PPA1
Reaction pageLeft to rightBalancedEC 3.6.1.1mitochondrial matrix
Human-GEM MAR06912CC BY 4.0Reference data
water+diphosphate(3-)proton+2phosphate(3-)
Catalysed by LHPP or PPA2 or PRUNE1 or PPA1
Reaction pageLeft to rightBalancedEC 3.6.1.1nucleus
Human-GEM MAR07794CC BY 4.0Reference data
diphosphate(3-)+water2hydrogenphosphate+hydron
Catalysed by ALPL or PPA1 or LHPP or PPA2
Reaction pageLeft to rightBalanced
Rhea RHEA:24576CC BY 4.0Reference data