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Proteins/UNIPROT:Q8IY57
Binds to MYC and inhibits MYC-mediated transactivation. Also binds to MYCN and enhances MYCN-dependent transcriptional activation. Increases calpain 2-mediated proteolysis of YY1 in vitro. Component of the E2F6.com-1 complex, a repressive complex that methylates 'Lys-9' of histone H3, suggesting that it is involved in chromatin-remodeling..
Function from UniProtKB (Q8IY57), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
145 statements
145 statements · 3 reference databases · Subject: YAF2 · Sources: gene ontology, Hetionet, Reactome
1 name
Resolves to: YAF2