Pathway
Metabolism of polyamines
Three polyamines - putrescine, spermine, and spermidine - are derived from ornithine by decarboxylation and condensation reactions. Arginine is metabolised similarly to form a fourth polyamine, agmatine. Polyamine levels are tightly regulated at the level of the enzyme ornithine decarboxylase (ODC).
REACT:R-HSA-351202Reactome
What the reference databases state
Statements
45 statements
45 statements · 1 reference database · Subject: Metabolism of polyamines · Sources: Reactome
- ADRM1 participates in Metabolism of polyaminesProteinReactome R-HSA-351202Inferred only
- AGMAT participates in Metabolism of polyaminesProteinReactome R-HSA-351202Inferred only
- AMD1 participates in Metabolism of polyaminesProteinReactome R-HSA-351202Inferred only
- AZIN1 participates in Metabolism of polyaminesProteinReactome R-HSA-351202Inferred only
- AZIN2 participates in Metabolism of polyaminesProteinReactome R-HSA-351202Inferred only
- NQO1 participates in Metabolism of polyaminesProteinReactome R-HSA-351202Inferred only
- OAZ1 participates in Metabolism of polyaminesProteinReactome R-HSA-351202Inferred only
- OAZ2 participates in Metabolism of polyaminesProteinReactome R-HSA-351202Inferred only
- OAZ3 participates in Metabolism of polyaminesProteinReactome R-HSA-351202Inferred only
- ODC1 participates in Metabolism of polyaminesProteinReactome R-HSA-351202Inferred only
- PAOX participates in Metabolism of polyaminesProteinReactome R-HSA-351202Inferred only
- PSMA1 participates in Metabolism of polyaminesProteinReactome R-HSA-351202Inferred only
Show the remaining 33
- PSMA2 participates in Metabolism of polyaminesProteinReactome R-HSA-351202Inferred only
- PSMA3 participates in Metabolism of polyaminesProteinReactome R-HSA-351202Inferred only
- PSMA4 participates in Metabolism of polyaminesProteinReactome R-HSA-351202Inferred only
- PSMA5 participates in Metabolism of polyaminesProteinReactome R-HSA-351202Inferred only
- PSMA6 participates in Metabolism of polyaminesProteinReactome R-HSA-351202Inferred only
- PSMA7 participates in Metabolism of polyaminesProteinReactome R-HSA-351202Inferred only
- PSMB1 participates in Metabolism of polyaminesProteinReactome R-HSA-351202Inferred only
- PSMB2 participates in Metabolism of polyaminesProteinReactome R-HSA-351202Inferred only
- PSMB3 participates in Metabolism of polyaminesProteinReactome R-HSA-351202Inferred only
- PSMB4 participates in Metabolism of polyaminesProteinReactome R-HSA-351202Inferred only
- PSMB5 participates in Metabolism of polyaminesProteinReactome R-HSA-351202Inferred only
- PSMB6 participates in Metabolism of polyaminesProteinReactome R-HSA-351202Inferred only
- PSMB7 participates in Metabolism of polyaminesProteinReactome R-HSA-351202Inferred only
- PSMC1 participates in Metabolism of polyaminesProteinReactome R-HSA-351202Inferred only
- PSMC2 participates in Metabolism of polyaminesProteinReactome R-HSA-351202Inferred only
- PSMC3 participates in Metabolism of polyaminesProteinReactome R-HSA-351202Inferred only
- PSMC4 participates in Metabolism of polyaminesProteinReactome R-HSA-351202Inferred only
- PSMC5 participates in Metabolism of polyaminesProteinReactome R-HSA-351202Inferred only
- PSMC6 participates in Metabolism of polyaminesProteinReactome R-HSA-351202Inferred only
- PSMD1 participates in Metabolism of polyaminesProteinReactome R-HSA-351202Inferred only
- PSMD11 participates in Metabolism of polyaminesProteinReactome R-HSA-351202Inferred only
- PSMD12 participates in Metabolism of polyaminesProteinReactome R-HSA-351202Inferred only
- PSMD13 participates in Metabolism of polyaminesProteinReactome R-HSA-351202Inferred only
- PSMD14 participates in Metabolism of polyaminesProteinReactome R-HSA-351202Inferred only
- PSMD2 participates in Metabolism of polyaminesProteinReactome R-HSA-351202Inferred only
- PSMD3 participates in Metabolism of polyaminesProteinReactome R-HSA-351202Inferred only
- PSMD6 participates in Metabolism of polyaminesProteinReactome R-HSA-351202Inferred only
- PSMD7 participates in Metabolism of polyaminesProteinReactome R-HSA-351202Inferred only
- PSMD8 participates in Metabolism of polyaminesProteinReactome R-HSA-351202Inferred only
- SAT1 participates in Metabolism of polyaminesProteinReactome R-HSA-351202Inferred only
- SEM1 participates in Metabolism of polyaminesProteinReactome R-HSA-351202Inferred only
- SMS participates in Metabolism of polyaminesProteinReactome R-HSA-351202Inferred only
- SRM participates in Metabolism of polyaminesProteinReactome R-HSA-351202Inferred only