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Proteins/UNIPROT:Q13123
Involved in pre-mRNA splicing as a component of the spliceosome. Auxiliary spliceosomal protein that regulates selection of alternative splice sites in a small set of target pre-mRNA species (Probable). Required for normal mitotic cell cycle progression. Recruits MAD1L1 and MAD2L1 to kinetochores, and is required to trigger the spindle assembly checkpoint. Required for normal accumulation of SMU1..
(Microbial infection) Required, together with SMU1, for normal splicing of influenza A virus NS1 pre-mRNA, which is required for the production of the exportin NS2 and for the production of influenza A virus particles. Not required for the production of VSV virus particles..
Function from UniProtKB (Q13123), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
54 statements
54 statements · 2 reference databases · Subject: IK · Sources: Hetionet, Reactome
5 names
Resolves to: IK