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Proteins/UNIPROT:Q96JS3
Transposase-derived from PiggyBac DNA transposons. Although it has been fully domesticated and lacks transposase activity, PGBD1 has acquired DNA-binding capability. It preferentially binds in and around genes involved in neuronal development, leading to their transcriptional pausing. Notably, PGBD1 suppresses paraspeckle assembly in neuronal cells..
Function from UniProtKB (Q96JS3), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
178 statements
178 statements · 2 reference databases · Subject: PGBD1 · Sources: gene ontology, Hetionet
2 names
Resolves to: PGBD1