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Proteins/UNIPROT:Q9H0R6
Catalytic subunit of the mitochondrial Glu-tRNA(Gln) amidotransferase complex GatCAB (Probable). GatCAB allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity). This subunit probably catalyzes the hydrolysis of the amido donor Gln, releasing ammonia that is sequestered within a channel in the GatCAB complex and made available to subunit B for downstream aminolysis of Glu-tRNA(Gln) (Probable). Required for the stability of GATB (By similarity)..
Function from UniProtKB (Q9H0R6), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
206 statements
206 statements · 2 reference databases · Subject: QRSL1 · Sources: Hetionet, Rhea
1 reaction
CHEBI:78520+L-glutamine+ATP(4-)+waterCHEBI:78521+L-glutamate(1-)+ADP(3-)+hydrogenphosphate+hydron
Catalysed by GATC or GATB or QRSL1
Reaction pageDirection not assertedBalanced
Rhea RHEA:17521CC BY 4.0Reference data
4 names
Resolves to: QRSL1