Compound
GDP-beta-L-fucose
A nucleotide-sugar oxoanion resulting from the removal of both of the hydrogens from the diphosphate group of GDP-β-L-fucose.
Definition from ChEBI (CHEBI:57273), read 2026-09-23. CC BY 4.0.
Structure
No depiction stored
Loading the model…
- Class
- Organic compound, anion
- Formula
- C16H23N5O15P2
- Mass
- 587.328 g/mol
- Charge
- -2
- InChIKey
- LQEBEXMHBLQMDB-JGQUBWHWSA-L
- SMILES
- C[C@@H]1O[C@H](OP(=O)([O-])OP(=O)([O-])OC[C@H]2O[C@@H](n3cnc4c(=O)nc(N)nc43)[C@H](O)[C@@H]2O)[C@@H](O)[C@H](O)[C@@H]1O
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
15 entities
15 entities reached.
0 reported hops15 assembled from the scaffold
- FUT3ProteinUNIPROT:P21217substrate ofInferred only98 paths7 endpoints
- FUT2ProteinUNIPROT:Q10981substrate ofInferred only88 paths7 endpoints
- FUT7ProteinUNIPROT:Q11130substrate ofInferred only48 paths6 endpoints
- FUT1ProteinUNIPROT:P19526substrate ofInferred only42 paths7 endpoints
- FUT9ProteinUNIPROT:Q9Y231substrate ofInferred only40 paths5 endpoints
- FUT8ProteinUNIPROT:Q9BYC5substrate ofInferred only32 paths16 endpoints
- FUT4ProteinUNIPROT:P22083substrate ofInferred only28 paths7 endpoints
- SLC35C1ProteinUNIPROT:Q96A29transported byInferred only21 paths21 endpoints
- FUT6ProteinUNIPROT:P51993substrate ofInferred only20 paths4 endpoints
- FUT5ProteinUNIPROT:Q11128substrate ofInferred only13 paths1 endpoint
- POFUT1ProteinUNIPROT:Q9H488substrate ofInferred only10 paths5 endpoints
- GFUSProteinUNIPROT:Q13630substrate ofInferred only8 paths8 endpoints
What the reference databases state
Statements
89 statements
89 statements · 1 reference database · Subject: GDP-beta-L-fucose · Sources: Rhea
- GDP-beta-L-fucose is a substrate of FUT1ProteinRhea RHEA:62964Inferred only
- GDP-beta-L-fucose is a substrate of FUT1ProteinRhea RHEA:32175Inferred only
- GDP-beta-L-fucose is a substrate of FUT1ProteinRhea RHEA:48304Inferred only
- GDP-beta-L-fucose is a substrate of FUT1ProteinRhea RHEA:48320Inferred only
- GDP-beta-L-fucose is a substrate of FUT1ProteinRhea RHEA:48292Inferred only
- GDP-beta-L-fucose is a substrate of FUT1ProteinRhea RHEA:50668Inferred only
- GDP-beta-L-fucose is a substrate of FUT2ProteinRhea RHEA:48292Inferred only
- GDP-beta-L-fucose is a substrate of FUT2ProteinRhea RHEA:62964Inferred only
- GDP-beta-L-fucose is a substrate of FUT2ProteinRhea RHEA:50668Inferred only
- GDP-beta-L-fucose is a substrate of FUT2ProteinRhea RHEA:32175Inferred only
- GDP-beta-L-fucose is a substrate of FUT2ProteinRhea RHEA:48800Inferred only
- GDP-beta-L-fucose is a substrate of FUT2ProteinRhea RHEA:48792Inferred only
Show the remaining 77
- GDP-beta-L-fucose is a substrate of FUT2ProteinRhea RHEA:62616Inferred only
- GDP-beta-L-fucose is a substrate of FUT2ProteinRhea RHEA:48304Inferred only
- GDP-beta-L-fucose is a substrate of FUT2ProteinRhea RHEA:48320Inferred only
- GDP-beta-L-fucose is a substrate of FUT2ProteinRhea RHEA:48324Inferred only
- GDP-beta-L-fucose is a substrate of FUT2ProteinRhea RHEA:50664Inferred only
- GDP-beta-L-fucose is a substrate of FUT2ProteinRhea RHEA:42040Inferred only
- GDP-beta-L-fucose is a substrate of FUT2ProteinRhea RHEA:42044Inferred only
- GDP-beta-L-fucose is a substrate of FUT3ProteinRhea RHEA:62904Inferred only
- GDP-beta-L-fucose is a substrate of FUT3ProteinRhea RHEA:56076Inferred only
- GDP-beta-L-fucose is a substrate of FUT3ProteinRhea RHEA:48824Inferred only
- GDP-beta-L-fucose is a substrate of FUT3ProteinRhea RHEA:52864Inferred only
- GDP-beta-L-fucose is a substrate of FUT3ProteinRhea RHEA:62844Inferred only
- GDP-beta-L-fucose is a substrate of FUT3ProteinRhea RHEA:62900Inferred only
- GDP-beta-L-fucose is a substrate of FUT3ProteinRhea RHEA:62824Inferred only
- GDP-beta-L-fucose is a substrate of FUT3ProteinRhea RHEA:23628Inferred only
- GDP-beta-L-fucose is a substrate of FUT3ProteinRhea RHEA:47888Inferred only
- GDP-beta-L-fucose is a substrate of FUT3ProteinRhea RHEA:47892Inferred only
- GDP-beta-L-fucose is a substrate of FUT3ProteinRhea RHEA:48328Inferred only
- GDP-beta-L-fucose is a substrate of FUT3ProteinRhea RHEA:62888Inferred only
- GDP-beta-L-fucose is a substrate of FUT3ProteinRhea RHEA:62896Inferred only
- GDP-beta-L-fucose is a substrate of FUT3ProteinRhea RHEA:14257Inferred only
- GDP-beta-L-fucose is a substrate of FUT4ProteinRhea RHEA:56076Inferred only
- GDP-beta-L-fucose is a substrate of FUT4ProteinRhea RHEA:14257Inferred only
- GDP-beta-L-fucose is a substrate of FUT4ProteinRhea RHEA:68044Inferred only
- GDP-beta-L-fucose is a substrate of FUT4ProteinRhea RHEA:62004Inferred only
- GDP-beta-L-fucose is a substrate of FUT5ProteinRhea RHEA:56076Inferred only
- GDP-beta-L-fucose is a substrate of FUT5ProteinRhea RHEA:14257Inferred only
- GDP-beta-L-fucose is a substrate of FUT5ProteinRhea RHEA:23628Inferred only
- GDP-beta-L-fucose is a substrate of FUT5ProteinRhea RHEA:48332Inferred only
- GDP-beta-L-fucose is a substrate of FUT5ProteinRhea RHEA:48336Inferred only
- GDP-beta-L-fucose is a substrate of FUT5ProteinRhea RHEA:48352Inferred only
- GDP-beta-L-fucose is a substrate of FUT5ProteinRhea RHEA:48364Inferred only
- GDP-beta-L-fucose is a substrate of FUT5ProteinRhea RHEA:48376Inferred only
- GDP-beta-L-fucose is a substrate of FUT5ProteinRhea RHEA:62904Inferred only
- GDP-beta-L-fucose is a substrate of FUT5ProteinRhea RHEA:52864Inferred only
- GDP-beta-L-fucose is a substrate of FUT5ProteinRhea RHEA:62900Inferred only
- GDP-beta-L-fucose is a substrate of FUT5ProteinRhea RHEA:62824Inferred only
- GDP-beta-L-fucose is a substrate of FUT5ProteinRhea RHEA:62836Inferred only
- GDP-beta-L-fucose is a substrate of FUT6ProteinRhea RHEA:64016Inferred only
- GDP-beta-L-fucose is a substrate of FUT6ProteinRhea RHEA:62824Inferred only
- GDP-beta-L-fucose is a substrate of FUT6ProteinRhea RHEA:64032Inferred only
- GDP-beta-L-fucose is a substrate of FUT6ProteinRhea RHEA:62836Inferred only
- GDP-beta-L-fucose is a substrate of FUT6ProteinRhea RHEA:52864Inferred only
- GDP-beta-L-fucose is a substrate of FUT6ProteinRhea RHEA:62888Inferred only
- GDP-beta-L-fucose is a substrate of FUT6ProteinRhea RHEA:14257Inferred only
- GDP-beta-L-fucose is a substrate of FUT6ProteinRhea RHEA:48368Inferred only
- GDP-beta-L-fucose is a substrate of FUT6ProteinRhea RHEA:48364Inferred only
- GDP-beta-L-fucose is a substrate of FUT6ProteinRhea RHEA:56076Inferred only
- GDP-beta-L-fucose is a substrate of FUT6ProteinRhea RHEA:48356Inferred only
- GDP-beta-L-fucose is a substrate of FUT7ProteinRhea RHEA:48392Inferred only
- GDP-beta-L-fucose is a substrate of FUT7ProteinRhea RHEA:56076Inferred only
- GDP-beta-L-fucose is a substrate of FUT7ProteinRhea RHEA:48356Inferred only
- GDP-beta-L-fucose is a substrate of FUT7ProteinRhea RHEA:62004Inferred only
- GDP-beta-L-fucose is a substrate of FUT7ProteinRhea RHEA:62008Inferred only
- GDP-beta-L-fucose is a substrate of FUT7ProteinRhea RHEA:62056Inferred only
- GDP-beta-L-fucose is a substrate of FUT7ProteinRhea RHEA:62060Inferred only
- GDP-beta-L-fucose is a substrate of FUT7ProteinRhea RHEA:52864Inferred only
- GDP-beta-L-fucose is a substrate of FUT8ProteinRhea RHEA:84135Inferred only
- GDP-beta-L-fucose is a substrate of FUT8ProteinRhea RHEA:12985Inferred only
- GDP-beta-L-fucose is a substrate of FUT9ProteinRhea RHEA:48388Inferred only
- GDP-beta-L-fucose is a substrate of FUT9ProteinRhea RHEA:68044Inferred only
- GDP-beta-L-fucose is a substrate of FUT9ProteinRhea RHEA:48380Inferred only
- GDP-beta-L-fucose is a substrate of FUT9ProteinRhea RHEA:48376Inferred only
- GDP-beta-L-fucose is a substrate of FUT9ProteinRhea RHEA:77187Inferred only
- GDP-beta-L-fucose is a substrate of FUT9ProteinRhea RHEA:56076Inferred only
- GDP-beta-L-fucose is a substrate of FUT9ProteinRhea RHEA:14257Inferred only
- GDP-beta-L-fucose is a substrate of FUT9ProteinRhea RHEA:77191Inferred only
- GDP-beta-L-fucose is a substrate of GFUSProteinRhea RHEA:18885Inferred only
- GDP-beta-L-fucose is a substrate of POFUT1ProteinRhea RHEA:63644Inferred only
- GDP-beta-L-fucose is a substrate of POFUT1ProteinRhea RHEA:70491Inferred only
- GDP-beta-L-fucose is a substrate of POFUT2ProteinRhea RHEA:63644Inferred only
- GDP-beta-L-fucose is a substrate of POFUT2ProteinRhea RHEA:70491Inferred only
- GDP-beta-L-fucose is a substrate of POFUT3ProteinRhea RHEA:70491Inferred only
- GDP-beta-L-fucose is a substrate of POFUT3ProteinRhea RHEA:63644Inferred only
- GDP-beta-L-fucose is a substrate of POFUT4ProteinRhea RHEA:63644Inferred only
- GDP-beta-L-fucose is a substrate of POFUT4ProteinRhea RHEA:70491Inferred only
- GDP-beta-L-fucose is transported by SLC35C1ProteinRhea RHEA:72707Inferred only
Reactions
79 reactions
N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein]+GDP-beta-L-fucosean N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-[alpha-L-Fuc-(1->6)]-beta-D-GlcNAc}-L-asparaginyl-[protein]+GDP+hydron
Catalysed by FUT8
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:12985CC BY 4.0Reference data
CHEBI:57268+GTP+hydronGDP-beta-L-fucose+diphosphate(3-)
Catalysed by FPGT
Reaction pageLeft to rightBalanced
Rhea RHEA:13549CC BY 4.0Reference data
a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative+GDP-beta-L-fucoseCHEBI:137941+GDP+hydron
Catalysed by FUT3 or FUT4 or FUT6 or FUT5 or FUT9
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:14257CC BY 4.0Reference data
GDP-beta-L-fucose+NADP(3-)CHEBI:57964+NADPH(4-)+hydron
Catalysed by GFUS
Reaction pageDirection not assertedBalanced
Rhea RHEA:18885CC BY 4.0Reference data
a beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl derivative+GDP-beta-L-fucoseCHEBI:140304+GDP+hydron
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:23628CC BY 4.0Reference data
N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein]+GDP-beta-L-fucoseN(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-[alpha-L-Fuc(1->3)]-beta-D-GlcNAc}-L-asparaginyl-[protein]+GDP+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:24444CC BY 4.0Reference data
a beta-D-Gal-(1->3)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(d18:1(4E))+GDP-beta-L-fucosealpha-L-fucosyl-(1->2)- beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine+GDP+hydron
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:32175CC BY 4.0Reference data
CHEBI:73988+GDP-beta-L-fucoseCHEBI:73991+GDP+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:36771CC BY 4.0Reference data
a ganglioside GM1 (d18:1(4E))+GDP-beta-L-fucosea ganglioside Fuc-GM1 (d18:1(4E))+GDP+hydron
Catalysed by FUT2
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:42040CC BY 4.0Reference data
a globoside GalGb4Cer (d18:1(4E))+GDP-beta-L-fucoseCHEBI:62649+GDP+hydron
Catalysed by FUT2
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:42044CC BY 4.0Reference data
N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acyl-sphing-4-enine+GDP-beta-L-fucoseCHEBI:88088+GDP+hydron
Catalysed by FUT3
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:47888CC BY 4.0Reference data
N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminosyl-(2->6)]-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acyl-sphing-4-enine+GDP-beta-L-fucoseCHEBI:88089+GDP+hydron
Catalysed by FUT3
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:47892CC BY 4.0Reference data
Where it reaches
9 systems, 15 regions, 21 tissues, 21 transporter routes — routes, not measurements: transporters known to carry GDP-beta-L-fucose are expressed there, and no source reports it arriving.
Loading the model…
Other names
2 names
Resolves to: GDP-beta-L-fucose
- Systematic name
- guanosine 5'-[3-(6-deoxy-beta-L-galactopyranosyl) diphosphate]guanosine 5'-[3-(6-deoxy-β-L-galactopyranosyl) diphosphate]