Compound
ITP
Inosine 5'-(tetrahydrogen triphosphate). An inosine nucleotide containing three phosphate groups esterified to the sugar moiety. Synonym: irppp.
Structure
No depiction stored
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- Class
- Organic compound, anion
- Formula
- C10H11N4O14P3
- Mass
- 504.134 g/mol
- Charge
- -4
- InChIKey
- HAEJPQIATWHALX-KQYNXXCUSA-J
- SMILES
- O=c1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)([O-])OP(=O)([O-])OP(=O)([O-])[O-])[C@@H](O)[C@H]1O
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
6 entities
6 entities reached.
0 reported hops6 assembled from the scaffold
- SLC25A36ProteinUNIPROT:Q96CQ1transported byInferred only39 paths39 endpoints
- ENTPD1ProteinUNIPROT:P49961substrate ofInferred only26 paths13 endpoints
- ENTPD2ProteinUNIPROT:Q9Y5L3substrate ofInferred only12 paths6 endpoints
- ENTPD3ProteinUNIPROT:O75355substrate ofInferred only10 paths5 endpoints
- ITPAProteinUNIPROT:Q9BY32substrate ofInferred only9 paths9 endpoints
- AK3ProteinUNIPROT:Q9UIJ7substrate ofInferred only2 paths2 endpoints
What the reference databases state
Statements
16 statements
16 statements · 1 reference database · Subject: ITP · Sources: Rhea
- IDP is converted to ITPCompoundRhea RHEA:30347Inferred only
- ITP is converted to IDPCompoundRhea RHEA:28330Inferred only
- IDP is converted to ITPCompoundRhea RHEA:29867Inferred only
- ITP is converted to IDPCompoundRhea RHEA:29867Inferred only
- ITP is converted to IMPCompoundRhea RHEA:29399Inferred only
- ITP is converted to IMPCompoundRhea RHEA:77735Inferred only
- ITP is a substrate of AK3ProteinRhea RHEA:29867Inferred only
- ITP is a substrate of ENTPD1ProteinRhea RHEA:28330Inferred only
- ITP is a substrate of ENTPD1ProteinRhea RHEA:77735Inferred only
- ITP is a substrate of ENTPD2ProteinRhea RHEA:77735Inferred only
- ITP is a substrate of ENTPD2ProteinRhea RHEA:28330Inferred only
- ITP is a substrate of ENTPD3ProteinRhea RHEA:28330Inferred only
Show the remaining 4
- ITP is a substrate of ENTPD3ProteinRhea RHEA:77735Inferred only
- ITP is a substrate of ITPAProteinRhea RHEA:29399Inferred only
- ITP is transported by SLC25A33ProteinRhea RHEA:73567Inferred only
- ITP is transported by SLC25A36ProteinRhea RHEA:73639Inferred only
Reactions
13 reactions
ATP(4-)+water+hydronITP+ammonium
Reaction pageDirection not assertedBalanced
Rhea RHEA:13037CC BY 4.0Reference data
ITP+waterIDP+hydrogenphosphate+hydron
Catalysed by ENTPD3 or ENTPD1 or ENTPD2
Reaction pageLeft to rightBalanced
Rhea RHEA:28330CC BY 4.0Reference data
ITP+waterIMP+diphosphate(3-)+hydron
Catalysed by ITPA
Reaction pageLeft to rightBalanced
Rhea RHEA:29399CC BY 4.0Reference data
Catalysed by AK3
Reaction pageDirection not assertedBalanced
Rhea RHEA:29867CC BY 4.0Reference data
Reaction pageLeft to rightBalanced
Rhea RHEA:30347CC BY 4.0Reference data
ITP+pyruvateIDP+phosphoenolpyruvate+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:56956CC BY 4.0Reference data
ITP+oxaloacetateIDP+phosphoenolpyruvate+carbon dioxide
Reaction pageDirection not assertedBalanced
Rhea RHEA:64864CC BY 4.0Reference data
Transported by SLC25A33
Reaction pageDirection not assertedBalanced
Rhea RHEA:73567CC BY 4.0Reference data
Transported by SLC25A36
Reaction pageDirection not assertedBalanced
Rhea RHEA:73639CC BY 4.0Reference data
ITP+N-acetyl-D-glucosamineIDP+N-acetyl-D-glucosamine 6-phosphate+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:74655CC BY 4.0Reference data
ITP+2waterIMP+2hydrogenphosphate+2hydron
Catalysed by ENTPD3 or ENTPD1 or ENTPD2
Reaction pageLeft to rightBalanced
Rhea RHEA:77735CC BY 4.0Reference data
CHEBI:58214+ITPCHEBI:233208+diphosphate(3-)
Reaction pageDirection not assertedBalanced
Rhea RHEA:83699CC BY 4.0Reference data
Where it reaches
7 systems, 13 regions, 39 tissues, 39 transporter routes — routes, not measurements: transporters known to carry ITP are expressed there, and no source reports it arriving.
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Other names
5 names
Resolves to: ITP
- Also called
- inosine 5'-triphosphateinosine 5'-triphosphate tetraanioninosine triphosphate(4-)inosine triphosphate(4−)ITP tetraanion