Compound

a ribonucleoside 5'-triphosphate

A ribonucleoside triphosphate oxoanion arising from global deprotonation of the triphosphate groups of any nucleoside triphosphate; major species at pH 7.3.

Definition from ChEBI (CHEBI:61557), read 2026-09-23. CC BY 4.0.

CHEBI:61557ChEBI

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Structure

2D depiction

Class: Organic compound, anion
Formula: C5H8O13P3R
Mass: 369.031 g/mol
Charge: -4
SMILES: *[C@@H]1O[C@H](COP(=O)([O-])OP(=O)([O-])OP(=O)([O-])[O-])[C@@H](O)[C@H]1O
Look it up: ChEBI

Identity from ChEBI. Not evidence.

Reactions

14 reactions

CHEBI:61560+[thioredoxin]-disulfide+watera ribonucleoside 5'-triphosphate+[thioredoxin]-dithiol
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:12701CC BY 4.0Reference data
a ribonucleoside 5'-triphosphate+AMPa ribonucleoside 5'-diphosphate+ADP(3-)
Catalysed by AK3
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:13749CC BY 4.0Reference data
a ribonucleoside 5'-diphosphate+ATP(4-)a ribonucleoside 5'-triphosphate+ADP(3-)
Catalysed by NME4 or NME6 or AK1 or NME1 or NME2 or AK4 or CMPK1 or NME3 or CMPK2 or AK9 or AK7 or AK8 and 1 more alternative
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:18113CC BY 4.0Reference data
2'-deoxycytidine+a ribonucleoside 5'-triphosphatedCMP+a ribonucleoside 5'-diphosphate+hydron
Catalysed by DCK
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:20061CC BY 4.0Reference data
RNA(n)+a ribonucleoside 5'-triphosphateRNA(n+1)+diphosphate(3-)
Catalysed by POLRMT or POLR3A or POLR1A or POLR2A or POLR2B or POLR1B or POLR3B
Reaction pageReversibleBalance undeterminable
Rhea RHEA:21248CC BY 4.0Reference data
a ribonucleoside 5'-triphosphate+watera ribonucleoside 5'-diphosphate+hydrogenphosphate+hydron
Catalysed by ENTPD3 or ENTPD1 or ENTPD8 or SMPDL3A or NTPCR or ENTPD7 or DDX20 or ENTPD4 or ENTPD2
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:23680CC BY 4.0Reference data
a ribonucleoside 5'-triphosphate+waterCHEBI:58043+diphosphate(3-)+hydron
Catalysed by ENPP3 or ENPP1 or NUDT15
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:23996CC BY 4.0Reference data
a ribonucleoside 5'-triphosphate+2waterCHEBI:58043+2hydrogenphosphate+2hydron
Catalysed by ENTPD3 or ENTPD1 or ENTPD8 or ENTPD2
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:36795CC BY 4.0Reference data
CHEBI:75483+a ribonucleoside 5'-triphosphateCHEBI:75434+a ribonucleoside 5'-diphosphate
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:38099CC BY 4.0Reference data
a ribonucleoside 5'-triphosphate+formate+hydronCHEBI:61560+carbon dioxide+water
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:51476CC BY 4.0Reference data
a ribonucleoside 5'-triphosphate+pyruvatea ribonucleoside 5'-diphosphate+phosphoenolpyruvate+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:56960CC BY 4.0Reference data
a 5'-end ribonucleotide-RNA+a ribonucleoside 5'-triphosphate+ATP(4-)+watera 5'-end phospho-ribonucleoside-ribonucleotide-RNA+AMP+2diphosphate(3-)+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:57528CC BY 4.0Reference data

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Other names

6 names

Resolves to: a ribonucleoside 5'-triphosphate

Also called: NTP tetraanionNTP(4-)NTP(4−)nucleoside 5'-triphosphate tetraanionnucleoside triphosphate(4-)nucleoside triphosphate(4−)