Loading the page.
Proteins/UNIPROT:P50226
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters. Is also responsible for the sulfonation and activation of minoxidil. Mediates the metabolic activation of carcinogenic N-hydroxyarylamines to DNA binding products and could so participate as modulating factor of cancer risk.
Function from UniProtKB (P50226), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
63 statements
63 statements · 7 reference databases · Subject: SULT1A2 · Sources: Bgee, Hetionet, Human Protein Atlas, Human-GEM, Reactome, Rhea, WikiPathways
5 reactions
3'-phospho-5'-adenylyl sulfate+4-nitrophenol4-nitrophenyl sulfate+proton+adenosine 3',5'-bismonophosphate
Catalysed by SULT1A1 or SULT1A2 or SULT1A4 or SULT1A3
Reaction pageLeft to rightBalancedEC 2.8.2.1cytosol
Human-GEM MAR07688CC BY 4.0Reference data
6 names
Resolves to: SULT1A2
Reaction pageLeft to rightBalancedEC 2.8.2.1cytosol
Human-GEM MAR07689CC BY 4.0Reference data
3'-phospho-5'-adenylyl sulfate+3,3',5-triiodo-L-thyronine3,3',5-triiodo-L-thyronine sulfate+proton+adenosine 3',5'-bismonophosphate
Catalysed by SULT1A1 or SULT1A2 or SULT1A4 or SULT1A3
Reaction pageLeft to rightBalancedEC 2.8.2.1cytosol
Human-GEM MAR08534CC BY 4.0Reference data
3'-phospho-5'-adenylyl sulfate+MAM03099cproton+adenosine 3',5'-bismonophosphate+MAM03100c
Catalysed by SULT1A1 or SULT1A2 or SULT1A4 or SULT1A3
Reaction pageLeft to rightBalancedEC 2.8.2.1cytosol
Human-GEM MAR08535CC BY 4.0Reference data
a phenol+3'-phosphoadenylyl sulfatean aryl sulfate+adenosine 3',5'-bisphosphate+hydron
Catalysed by SULT1C2 or SULT1B1 or SULT1C4 or SULT1A3 or SULT1A4 or SULT1A1 or SULT1A2 or SULT1C3
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:12164CC BY 4.0Reference data