1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

298 compounds within 3 steps: 2 in 1, 42 in 2, 254 in 3

Three steps

1-octadecanoyl-2-(15-hydroperoxy-5Z,8Z,11Z,13E-eicosatetraenoyl)-sn-glycero-3-phosphocholineReach from here →
1. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
2. 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + CoA
3. 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + O2 = 1-octadecanoyl-2-(15-hydroperoxy-5Z,8Z,11Z,13E-eicosatetraenoyl)-sn-glycero-3-phosphocholine
Catalysed by LPGAT1, ALOX15B
cholesteryl (7Z)-octadecenoateReach from here →
1. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
2. stearoyl-CoA 9-desaturase (stearoyl-CoA)
3. (7Z)-octadecenoyl-CoA + cholesterol = cholesteryl (7Z)-octadecenoate + CoA
Catalysed by LPGAT1, SCD, SCD5, SOAT1cytosol
CHEBI:15345Reach from here →
1. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
2. Stearoyl-CoA hydrolase
3. Acetoacetate:CoA ligase (AMP-forming)
Catalysed by LPGAT1, ACOT7, BAAT, THEM4 and 3 morecytosolOne of 2 routes
cholineReach from here →
1. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
2. Stearoyl-CoA hydrolase
3. Acetyl-CoA:choline O-acetyltransferase
Catalysed by LPGAT1, ACOT7, BAAT, THEM4 and 3 morecytosol, nucleus
CHEBI:15380Reach from here →
1. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
2. Stearoyl-CoA hydrolase
3. 5-aminolevulinate synthase (2-amino-3-oxoadipate)
Catalysed by LPGAT1, ACOT7, BAAT, THEM4 and 4 morecytosol, mitochondrial matrixOne of 8 routes
CHEBI:15477Reach from here →
1. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
2. Stearoyl-CoA hydrolase
3. glycine N-acyltransferase (2-methylbutyryl-CoA)
Catalysed by LPGAT1, ACOT7, BAAT, THEM4 and 5 morecytosol, mitochondrial matrixOne of 2 routes
2-methylcrotonoyl-CoAReach from here →
1. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
2. Stearoyl-CoA hydrolase
3. Production of Tiglylcarnitine
Catalysed by LPGAT1, ACOT7, BAAT, THEM4 and 4 morecytosolOne of 2 routes
isobutyryl-CoAReach from here →
1. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
2. Stearoyl-CoA hydrolase
3. acetyl-CoA C-acyltransferase (3-oxo-4-methyl-pentanoyl-CoA)
Catalysed by LPGAT1, ACOT7, BAAT, THEM4 and 5 morecytosol, mitochondrial matrixOne of 3 routes
3-methylbut-2-enoyl-CoAReach from here →
1. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
2. Stearoyl-CoA hydrolase
3. glycine-N-acyltransferase (3-methylcrotonoylglycine)
Catalysed by LPGAT1, ACOT7, BAAT, THEM4 and 3 morecytosol, mitochondrial matrix
isovaleryl-CoAReach from here →
1. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
2. Stearoyl-CoA hydrolase
3. glycine N-acyltransferase (isovalerylglycine)
Catalysed by LPGAT1, ACOT7, BAAT, THEM4 and 5 morecytosol, mitochondrial matrixOne of 3 routes
arachidonoyl-CoAReach from here →
1. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
2. Stearoyl-CoA hydrolase
3. Arachidonate:CoA ligase (AMP-forming)
Catalysed by LPGAT1, ACOT7, BAAT, THEM4 and 10 morecytosolOne of 12 routes
CHEBI:15519Reach from here →
1. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
2. Stearoyl-CoA hydrolase
3. propanoyl-CoA C-acyltransferase
Catalysed by LPGAT1, ACOT7, BAAT, THEM4 and 5 morecytosol, peroxisomeOne of 2 routes
phenylacetyl-CoAReach from here →
1. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
2. Stearoyl-CoA hydrolase
3. Phenylacetate:CoA ligase
Catalysed by LPGAT1, ACOT7, BAAT, THEM4 and 2 morecytosolOne of 3 routes
propionyl-CoAReach from here →
1. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
2. Stearoyl-CoA hydrolase
3. Propanoate:CoA ligase (AMP-forming)
Catalysed by LPGAT1, ACOT7, BAAT, THEM4 and 5 morecytosolOne of 43 routes
1-(10Z-heptadecenoyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamineReach from here →
1. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-(10Z-heptadecenoyl)-sn-glycero-3-phosphoethanolamine + (9Z)-octadecenoyl-CoA = 1-(10Z-heptadecenoyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by LPGAT1, SCD, SCD5, MBOAT1
CHEBI:15650Reach from here →
1. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
2. Stearoyl-CoA hydrolase
3. N-acetyl-LTE4 to leukotriene E4 conversion
Catalysed by LPGAT1, ACOT7, BAAT, THEM4 and 34 morecytosolOne of 2 routes
S-(9Z-octadecenoyl)-4'-phosphopantetheineReach from here →
1. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. (9Z)-octadecenoyl-CoA + H2O = S-(9Z-octadecenoyl)-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)
Catalysed by LPGAT1, SCD, SCD5, FITM2
CHEBI:15727Reach from here →
1. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
2. Stearoyl-CoA hydrolase
3. N-alpha-acetyltransferase 10, NatA catalytic subunit (acetylcarnosine)
Catalysed by LPGAT1, ACOT7, BAAT, THEM4 and 3 morecytosol
CHEBI:15746Reach from here →
1. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
2. Stearoyl-CoA hydrolase
3. diamine N-acetyltransferase (N1-acetylspermine)
Catalysed by LPGAT1, ACOT7, BAAT, THEM4 and 4 morecytosolOne of 2 routes
hexadecanoic acidReach from here →
1. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
2. Beta Oxidation of Long Chain Fatty Acid
3. Palmitoyl-CoA hydrolase
Catalysed by LPGAT1, ACAA1, HSD17B4, EHHADH and 6 moreperoxisome, cytosolOne of 2 routes
1-acylglycerone 3-phosphateReach from here →
1. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
2. acyl-CoA pool formation and breakdown
3. Acyl-CoA:glycerone-phosphate O-acyltransferase
Catalysed by LPGAT1, GNPATcytosol
phosphatidylethanolamineReach from here →
1. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
2. acyl-CoA pool formation and breakdown
3. Acyl-CoA:1-acyl-sn-glycero-3-phosphoethanolamine O-acyltransferase
Catalysed by LPGAT1, LPCAT4, LPCAT3, LPCAT2 and 1 morecytosol
1,2-diacyl-sn-glycero-3-phosphocholine(1+)Reach from here →
1. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
2. acyl-CoA pool formation and breakdown
3. Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase
Catalysed by LPGAT1, LPCAT4, LPCAT3, LPCAT2 and 1 morecytosol
cholesterolReach from here →
1. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
2. sphing-4-enine + octadecanoyl-CoA = N-octadecanoylsphing-4-enine + CoA + H(+)
3. beta-D-glucosyl-(1<->1)-N-octadecanoylsphing-4-enine + cholesterol = cholesteryl 3-beta-D-glucoside + N-octadecanoylsphing-4-enine
Catalysed by LPGAT1, CERS1, TLCD3B, CERS2 and 2 more
hexadecan-1-olReach from here →
1. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
2. Beta Oxidation of Long Chain Fatty Acid
3. formate dehydrogenase (palmitoyl-CoA)
Catalysed by LPGAT1, ACAA1, HSD17B4, EHHADH and 3 moreperoxisome
11-cis-retinyl hexadecanoateReach from here →
1. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
2. Beta Oxidation of Long Chain Fatty Acid
3. Palmitoyl-CoA:retinol O-acyltransferase
Catalysed by LPGAT1, ACAA1, HSD17B4, EHHADH and 6 moreperoxisome, cytosol
11-cis-retinolReach from here →
1. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
2. Stearoyl-CoA hydrolase
3. Palmitoyl-CoA:retinol O-acyltransferase
Catalysed by LPGAT1, ACOT7, BAAT, THEM4 and 7 morecytosol
phosphatidic acidReach from here →
1. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
2. acyl-CoA pool formation and breakdown
3. acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase
Catalysed by LPGAT1, AGPAT2, LCLAT1, MBOAT1 and 6 morecytosol, mitochondrial matrixOne of 7 routes
(R)-carnitineReach from here →
1. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
2. (R)-carnitine + octadecanoyl-CoA = O-octadecanoyl-(R)-carnitine + CoA
3. (R)-carnitine + octadecanoyl-CoA = O-octadecanoyl-(R)-carnitine + CoA
Catalysed by LPGAT1, CPT2
oxaloacetateReach from here →
1. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
2. Stearoyl-CoA hydrolase
3. ATP citrate lyase (citrate)
Catalysed by LPGAT1, ACOT7, BAAT, THEM4 and 3 morecytosol
1-acyl-sn-glycerol 3-phosphateReach from here →
1. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
2. glycerol-3-phosphate 1-O-acyltransferase (sn-glycerol-3-phosphate)
3. 1-acylglycerol-3P-LD-TG1 pool (liver tissue) formation
Catalysed by LPGAT1, GPAT3, GPAT2, GPAT4 and 1 morecytosolOne of 9 routes
a cholesterol esterReach from here →
1. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
2. Acyl-CoA:cholesterol O-acyltransferase
3. cholesterol-ester plasma pool to cholesterol-ester-10,13,16,19-docosa conversion
Catalysed by LPGAT1, SOAT2, SOAT1endoplasmic reticulumOne of 4 routes
octadecanalReach from here →
1. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
2. Stearoyl-CoA hydrolase
3. octadecanal + NAD(+) + H2O = octadecanoate + NADH + 2 H(+)
Catalysed by LPGAT1, ACOT7, BAAT, THEM4 and 3 morecytosol
anilineReach from here →
1. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
2. Stearoyl-CoA hydrolase
3. Acetyl-CoA:arylamine N-acetyltransferase
Catalysed by LPGAT1, ACOT7, BAAT, THEM4 and 4 morecytosol
CHEBI:17312Reach from here →
1. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
2. Stearoyl-CoA hydrolase
3. N1,N12-diacetylspermine to N1-acetylspermine conversion
Catalysed by LPGAT1, ACOT7, BAAT, THEM4 and 2 morecytosolOne of 2 routes
1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphoethanolamineReach from here →
1. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
2. acyl-CoA pool formation and breakdown
3. Acyl-CoA:1-alkenylglycerophosphoethanolamine O-acyltransferase
Catalysed by LPGAT1, LPCAT4, LPCAT3, LPCAT2 and 1 morecytosol
O-hexadecanoyl-(R)-carnitineReach from here →
1. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
2. Beta Oxidation of Long Chain Fatty Acid
3. palmitoyl-CoA:L-carnitine O-palmitoyltransferase
Catalysed by LPGAT1, ACAA1, HSD17B4, EHHADH and 3 moreperoxisomeOne of 4 routes
L-cysteineReach from here →
1. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
2. Stearoyl-CoA hydrolase
3. N-acetylglutamate synthase (N-acetyl-L-cysteine)
Catalysed by LPGAT1, ACOT7, BAAT, THEM4 and 3 morecytosol, mitochondrial matrix
(7Z,10Z,13Z)-hexadecatrienoyl-CoAReach from here →
1. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
2. Stearoyl-CoA hydrolase
3. Fatty Acid Beta Oxidation (C18:3->C16:3), Mitochondrial
Catalysed by LPGAT1, ACOT7, BAAT, THEM4 and 5 morecytosol, mitochondrial matrix
a 1,2-diacyl-sn-glycerolReach from here →
1. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
2. acyl-CoA pool formation and breakdown
3. a 2-acylglycerol + an acyl-CoA = a 1,2-diacyl-sn-glycerol + CoA
Catalysed by LPGAT1, MOGAT2, AWAT2, MOGAT1cytosol
a triacylglycerolReach from here →
1. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
2. acyl-CoA pool formation and breakdown
3. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
Catalysed by LPGAT1, DGAT1, MOGAT2, MOGAT3 and 2 morecytosol
CHEBI:17927Reach from here →
1. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
2. Stearoyl-CoA hydrolase
3. N1,N8-diacetylspermidine to N1-acetylspermidine conversion
Catalysed by LPGAT1, ACOT7, BAAT, THEM4 and 2 morecytosol
1-(9Z-octadecenoyl)-3-octadecanoyl-sn-glycerolReach from here →
1. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 3-octadecanoyl-sn-glycerol + (9Z)-octadecenoyl-CoA = 1-(9Z-octadecenoyl)-3-octadecanoyl-sn-glycerol + CoA
Catalysed by LPGAT1, SCD, SCD5, MOGAT1
1-octanoyl-3-(9Z-octadecenoyl)-glycerolReach from here →
1. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-octanoylglycerol + (9Z)-octadecenoyl-CoA = 1-octanoyl-3-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by LPGAT1, SCD, SCD5, MOGAT2
1-dodecanoyl-3-(9Z-octadecenoyl)-glycerolReach from here →
1. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-dodecanoylglycerol + (9Z)-octadecenoyl-CoA = 1-dodecanoyl-3-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by LPGAT1, SCD, SCD5, MOGAT2 and 1 more
1-octadecanoyl-3-(9Z-octadecenoyl)-glycerolReach from here →
1. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-octadecanoylglycerol + (9Z)-octadecenoyl-CoA = 1-octadecanoyl-3-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by LPGAT1, SCD, SCD5, MOGAT2 and 1 more
1-(9Z,12Z,15Z-octadecatrienoyl)-3-(9Z-octadecenoyl)-glycerolReach from here →
1. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-(9Z,12Z,15Z-octadecatrienoyl)-glycerol + (9Z)-octadecenoyl-CoA = 1-(9Z,12Z,15Z-octadecatrienoyl)-3-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by LPGAT1, SCD, SCD5, MOGAT2 and 1 more
1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-3-(9Z-octadecenoyl)-glycerolReach from here →
1. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + (9Z)-octadecenoyl-CoA = 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-3-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by LPGAT1, SCD, SCD5, MOGAT2
1-tetradecanoyl-3-(9Z-octadecenoyl)-glycerolReach from here →
1. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-tetradecanoylglycerol + (9Z)-octadecenoyl-CoA = 1-tetradecanoyl-3-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by LPGAT1, SCD, SCD5, MOGAT2
1-O-(9Z-octadecyl)-3-(9Z-octadecenoyl)-glycerolReach from here →
1. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-O-(9Z-octadecenyl)-glycerol + (9Z)-octadecenoyl-CoA = 1-O-(9Z-octadecyl)-3-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by LPGAT1, SCD, SCD5, DGAT1 and 5 more