beta-D-glucosyl-(1<->1)-sphing-4-enine

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

134 compounds within 3 steps: 2 in 1, 25 in 2, 107 in 3

Three steps

dTDPReach from here →
1. beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose
2. dATP:D-glucose 6-phosphotransferase
3. nucleoside-diphosphate kinase (dADP)
Catalysed by GBA3, HK1, HK2, HK3 and 7 morecytosolOne of 3 routes
dodecanoateReach from here →
1. beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose
2. N-dodecanoylsphing-4-enine + H2O = dodecanoate + sphing-4-enine
3. H2O[c] + N-dodecanoylsphing-4-enine[c] = lauric acid[c] + sphingosine[c]
Catalysed by GBA3, NAAA, ASAH1, ACER2 and 1 morecytosolOne of 2 routes
D-glucosyl-N-acylsphingosineReach from here →
1. beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose
2. sphing-4-enine + a fatty acyl-CoA = an N-acylsphing-4-enine + CoA + H(+)
3. UDP-glucose:N-acylsphingosine D-glucosyltransferase
Catalysed by GBA3, CERS1, CERS6, CERS3 and 4 morecytosolOne of 2 routes
a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enineReach from here →
1. beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose
2. sphing-4-enine + a fatty acyl-CoA = an N-acylsphing-4-enine + CoA + H(+)
3. an N-acylsphing-4-enine + UDP-alpha-D-galactose = a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + UDP + H(+)
Catalysed by GBA3, CERS1, CERS6, CERS3 and 4 moreOne of 2 routes
D-gluconateReach from here →
1. beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose
2. D-glucose + NAD(+) = D-glucono-1,5-lactone + NADH + H(+)
3. D-glucono-1,5-lactone + H2O = D-gluconate + H(+)
Catalysed by GBA3, H6PD, RGN
a beta-D-xylosyl-(1<->1')-N-acylsphing-4-enineReach from here →
1. beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose
2. sphing-4-enine + a fatty acyl-CoA = an N-acylsphing-4-enine + CoA + H(+)
3. a beta-D-xylosyl-(1<->1')-N-acylsphing-4-enine + cholesterol = cholesteryl 3-beta-D-xyloside + an N-acylsphing-4-enine
Catalysed by GBA3, CERS1, CERS6, CERS3 and 4 moreOne of 2 routes
beta-D-xylosyl-(1<->1')-N-(9Z-octadecenoyl)-sphing-4-enineReach from here →
1. beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose
2. N-(9Z-octadecenoyl)-sphing-4-enine + H2O = sphing-4-enine + (9Z)-octadecenoate
3. N-(9Z-octadecenoyl)-sphing-4-enine + UDP-alpha-D-xylose = beta-D-xylosyl-(1<->1')-N-(9Z-octadecenoyl)-sphing-4-enine + UDP + H(+)
Catalysed by GBA3, ASAH1, ACER2, ACER1 and 3 more
a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enineReach from here →
1. beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose
2. sphing-4-enine + a fatty acyl-CoA = an N-acylsphing-4-enine + CoA + H(+)
3. an N-acylsphing-4-enine + UDP-alpha-D-glucose = a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + UDP + H(+)
Catalysed by GBA3, CERS1, CERS6, CERS3 and 4 moreOne of 2 routes
NAADPHReach from here →
1. beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose
2. D-glucose + ADP = D-glucose 6-phosphate + AMP + H(+)
3. NAADP(+) + D-glucose 6-phosphate = NAADPH + 6-phospho-D-glucono-1,5-lactone + H(+)
Catalysed by GBA3, ADPGK, G6PD
octadecanoateReach from here →
1. beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose
2. sphing-4-enine + octadecanoyl-CoA = N-octadecanoylsphing-4-enine + CoA + H(+)
3. N-octadecanoylsphing-4-enine + H2O = sphing-4-enine + octadecanoate
Catalysed by GBA3, CERS1, TLCD3B, CERS2 and 4 more
beta-D-galactoseReach from here →
1. beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose
2. D-glucose + UDP-alpha-D-galactose = lactose + UDP + H(+)
3. lactose + H2O = beta-D-galactose + D-glucose
Catalysed by GBA3, B4GALT2, B4GALT1, LCT
elaidic acidReach from here →
1. beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose
2. N-(9Z-octadecenoyl)-sphing-4-enine + H2O = sphing-4-enine + (9Z)-octadecenoate
3. H2O[g] + N-(9Z-octadecenoyl)-sphing-4-enine[g] = elaidate[g] + sphingosine[g]
Catalysed by GBA3, ASAH1, ACER2, ACER1 and 2 moreGolgi apparatus
alpha-D-galactoseReach from here →
1. beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose
2. UDP-alpha-D-galactose:D-glucose 4-beta-D-galactosyltransferase
3. Lactose galactohydrolase
Catalysed by GBA3, B4GALT2, LALBA, B4GALT1 and 4 moreGolgi apparatus, extracellular spaceOne of 3 routes
1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholineReach from here →
1. beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose
2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
3. 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine
Catalysed by GBA3, PAFAH2, PLA2G15One of 3 routes
beta-D-fructoseReach from here →
1. beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose
2. Aldehyde Reductase
3. D-Glucitol:NAD+ 2-oxidoreductase
Catalysed by GBA3, SORDcytosol
a fatty acidReach from here →
1. beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose
2. sphing-4-enine + a fatty acyl-CoA = an N-acylsphing-4-enine + CoA + H(+)
3. an N-acylsphing-4-enine + H2O = sphing-4-enine + a fatty acid
Catalysed by GBA3, CERS1, CERS6, CERS3 and 9 more
phosphocholineReach from here →
1. beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose
2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
3. 1-O-hexadecyl-sn-glycero-3-phosphocholine + H2O = 1-O-hexadecyl-sn-glycerol + phosphocholine + H(+)
Catalysed by GBA3, PAFAH2, SMPD2
acetateReach from here →
1. beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose
2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
3. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
Catalysed by GBA3, PAFAH2, ASAH1
tetradecanoateReach from here →
1. beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose
2. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
3. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
Catalysed by GBA3, ASAH1, ACER2, ASAH2
(9Z)-octadecenoateReach from here →
1. beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose
2. N-(9Z-octadecenoyl)-sphing-4-enine + H2O = sphing-4-enine + (9Z)-octadecenoate
3. H2O[r] + N-(9Z-octadecenoyl)-sphing-4-enine[r] = oleate[r] + sphingosine[r]
Catalysed by GBA3, ASAH1, ACER2, ACER1 and 2 moreendoplasmic reticulumOne of 2 routes
tetracosanoateReach from here →
1. beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose
2. tetracosanoyl-CoA + sphing-4-enine = N-tetracosanoyl-sphing-4-enine + CoA + H(+)
3. N-tetracosanoyl-sphing-4-enine + H2O = tetracosanoate + sphing-4-enine
Catalysed by GBA3, CERS2, ACER2, ACER1
eicosanoateReach from here →
1. beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose
2. eicosanoyl-CoA + sphing-4-enine = N-eicosanoyl-sphing-4-enine + CoA + H(+)
3. N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
Catalysed by GBA3, TLCD3B, CERS2, ACER2
(15Z)-tetracosenoateReach from here →
1. beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose
2. N-(15Z-tetracosenoyl)-sphing-4-enine + H2O = (15Z)-tetracosenoate + sphing-4-enine
3. N-(15Z-tetracosenoyl)-sphing-4-enine + H2O = (15Z)-tetracosenoate + sphing-4-enine
Catalysed by GBA3, ACER2, ACER1, ASAH2
1-O-hexadecyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphocholineReach from here →
1. beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose
2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
3. 1-O-hexadecyl-sn-glycero-3-phosphocholine + (9Z)-octadecenoyl-CoA = 1-O-hexadecyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by GBA3, PAFAH2, LPCAT4
1-O-hexadecyl-sn-glycerolReach from here →
1. beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose
2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
3. 1-O-hexadecyl-sn-glycero-3-phosphocholine + H2O = 1-O-hexadecyl-sn-glycerol + phosphocholine + H(+)
Catalysed by GBA3, PAFAH2, SMPD2
fatty acidReach from here →
1. beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose
2. sphing-4-enine + a fatty acyl-CoA = an N-acylsphing-4-enine + CoA + H(+)
3. N-Acylsphingosine amidohydrolase
Catalysed by GBA3, CERS1, CERS6, CERS3 and 4 morelysosome
1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholineReach from here →
1. beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose
2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
3. 1-O-hexadecyl-sn-glycero-3-phosphocholine + acetyl-CoA = 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + CoA
Catalysed by GBA3, PAFAH2, LPCAT2, LPCAT1
keto-D-fructoseReach from here →
1. beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose
2. Aldehyde Reductase
3. keto-D-fructose + NADH + H(+) = D-sorbitol + NAD(+)
Catalysed by GBA3, SORDcytosol
1-O-hexadecyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholineReach from here →
1. beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose
2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
3. 1-O-hexadecyl-sn-glycero-3-phosphocholine + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-O-hexadecyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by GBA3, PAFAH2, LPCAT4One of 2 routes
dCMPReach from here →
1. beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose
2. dATP:D-glucose 6-phosphotransferase
3. cytidine/uridine monophosphate kinase (dADP)
Catalysed by GBA3, HK1, HK2, HK3 and 2 morecytosolOne of 2 routes
dGMPReach from here →
1. beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose
2. dATP:D-glucose 6-phosphotransferase
3. dADP to dATP conversion
Catalysed by GBA3, HK1, HK2, HK3 and 1 morecytosol, mitochondrial matrix
an N-acylsphing-4-enine 1-phosphateReach from here →
1. beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose
2. sphing-4-enine + a fatty acyl-CoA = an N-acylsphing-4-enine + CoA + H(+)
3. an N-acylsphing-4-enine + ATP = an N-acylsphing-4-enine 1-phosphate + ADP + H(+)
Catalysed by GBA3, CERS1, CERS6, CERS3 and 5 more
a 2-acyl-sn-glycero-3-phosphocholineReach from here →
1. beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose
2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
3. N-(acetyl)-sphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 2-acyl-sn-glycero-3-phosphocholine
Catalysed by GBA3, PAFAH2, PLA2G15
6-phospho-D-glucono-1,5-lactoneReach from here →
1. beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose
2. ATP:D-glucose 6-phosphotransferase
3. D-glucose-6-phosphate:NADP+ 1-oxidoreductase
Catalysed by GBA3, HK1, GCK, HK2 and 3 morecytosol, endoplasmic reticulumOne of 6 routes
a 1-acyl-sn-glycero-3-phosphocholineReach from here →
1. beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose
2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
3. N-(acetyl)-sphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 1-acyl-sn-glycero-3-phosphocholine
Catalysed by GBA3, PAFAH2, PLA2G15
phosphoethanolamineReach from here →
1. beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose
2. sphing-4-enine + ATP = sphing-4-enine 1-phosphate + ADP + H(+)
3. sphing-4-enine 1-phosphate = (2E)-hexadecenal + phosphoethanolamine
Catalysed by GBA3, SPHK2, SPHK1, SGPL1
an acyl-CoAReach from here →
1. beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose
2. sphing-4-enine + a fatty acyl-CoA = an N-acylsphing-4-enine + CoA + H(+)
3. acyl-CoA:sphingosine N-acyltransferase
Catalysed by GBA3, CERS1, CERS6, CERS3 and 7 moreGolgi apparatusOne of 2 routes
1D-myo-inositol 3-phosphateReach from here →
1. beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose
2. ATP:D-glucose 6-phosphotransferase
3. 1D-myo-inositol-3-phosphate lyase (isomerizing)
Catalysed by GBA3, HK1, GCK, HK2 and 3 morecytosolOne of 2 routes
D-mannose 6-phosphateReach from here →
1. beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose
2. D-glucose + ADP = D-glucose 6-phosphate + AMP + H(+)
3. D-glucose 6-phosphate = D-mannose 6-phosphate
Catalysed by GBA3, ADPGK, GPI
dTMPReach from here →
1. beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose
2. dATP:D-glucose 6-phosphotransferase
3. deoxythymidylate kinase (dADP)
Catalysed by GBA3, HK1, HK2, HK3 and 2 morecytosol, mitochondrial matrixOne of 2 routes
a 1-acyl-sn-glycero-3-phospho-L-serineReach from here →
1. beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose
2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
3. a 1,2-diacyl-sn-glycero-3-phospho-L-serine + N-(acetyl)-sphing-4-enine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 1-acyl-sn-glycero-3-phospho-L-serine
Catalysed by GBA3, PAFAH2, PLA2G15
a 1-acyl-sn-glycero-3-phosphoethanolamineReach from here →
1. beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose
2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
3. N-(acetyl)-sphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 1-acyl-sn-glycero-3-phosphoethanolamine
Catalysed by GBA3, PAFAH2, PLA2G15
1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose
2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
3. a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + N-(acetyl)-sphing-4-enine = 1-O-acyl-N-(acetyl)-sphing-4-enine + 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)
Catalysed by GBA3, PAFAH2, PLA2G15
a 2-acyl-sn-glycero-3-phosphoethanolamineReach from here →
1. beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose
2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
3. N-(acetyl)-sphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 2-acyl-sn-glycero-3-phosphoethanolamine
Catalysed by GBA3, PAFAH2, PLA2G15
a 2-acyl-sn-glycero-3-phospho-L-serineReach from here →
1. beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose
2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
3. a 1,2-diacyl-sn-glycero-3-phospho-L-serine + N-(acetyl)-sphing-4-enine = a 2-acyl-sn-glycero-3-phospho-L-serine + 1-O-acyl-N-(acetyl)-sphing-4-enine
Catalysed by GBA3, PAFAH2, PLA2G15
CHEBI:67119Reach from here →
1. beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose
2. UDP-alpha-D-galactose:sphingosine 1-beta-galactosyltransferase
3. UDP-alpha-D-galactose:sphingosine 1-beta-galactosyltransferase
Catalysed by GBA3cytosol
1-O-hexadecyl-2-hexadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose
2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
3. 1-O-hexadecyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1-O-hexadecyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by GBA3, PAFAH2, LPCAT1One of 3 routes
1-octadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose
2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
3. 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + N-(acetyl)-sphing-4-enine = 1-octadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine
Catalysed by GBA3, PAFAH2, PLA2G15
N-(hexadecanoyl)-sphing-4-enine-1-phosphateReach from here →
1. beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose
2. sphing-4-enine + hexadecanoyl-CoA = N-hexadecanoylsphing-4-enine + CoA + H(+)
3. N-hexadecanoylsphing-4-enine + ATP = N-(hexadecanoyl)-sphing-4-enine-1-phosphate + ADP + H(+)
Catalysed by GBA3, CERS6, TLCD3B, CERS5 and 2 more
1-hexadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose
2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
3. 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphocholine
Catalysed by GBA3, PAFAH2, PLA2G15One of 4 routes