glycodeoxycholate

1. Glycodeoxycholate amidohydrolase
2. transport of alanine and glycine (cytosol to extracellular)

Catalysed by SLC3A2, SLC7A5, SLC7A10cytosol, extracellular spaceOne of 6 routes

1. Glycodeoxycholate amidohydrolase
2. leukotriene C4 hydrolysis

No catalyst recordedcytosolOne of 2 routes

1. Glycodeoxycholate amidohydrolase
2. transport of asparagine and glycine (cytosol to extracellular)

No catalyst recordedcytosol, extracellular spaceOne of 4 routes

1. Glycodeoxycholate amidohydrolase
2. transport of glycine and phenylalanine (cytosol to extracellular)

Catalysed by SLC7A5cytosol, extracellular spaceOne of 7 routes

1. glycodeoxycholate(in) + glutathione(in) + ATP + H2O = glycodeoxycholate(out) + glutathione(out) + ADP + phosphate + H(+)
2. 2 glutathione + NADP(+) = glutathione disulfide + NADPH + H(+)

Catalysed by ABCC4, GSRinner side of the membrane, outer side of the membraneOne of 22 routes

1. Glycodeoxycholate amidohydrolase
2. L-tyrosine + glyoxylate = 3-(4-hydroxyphenyl)pyruvate + glycine

Catalysed by AADATcytosol

1. Glycodeoxycholate amidohydrolase
2. N(omega),N(omega)-dimethyl-L-arginine + glyoxylate = 5-(3,3-dimethylguanidino)-2-oxopentanoate + glycine

Catalysed by AGXT2cytosol

1. glycodeoxycholate(in) + glutathione(in) + ATP + H2O = glycodeoxycholate(out) + glutathione(out) + ADP + phosphate + H(+)
2. glutathione = L-cysteinylglycine + 5-oxo-L-proline

Catalysed by ABCC4, CHAC2, CHAC1inner side of the membrane, outer side of the membrane

1. Glycodeoxycholate amidohydrolase
2. cholate-CoA ligase (3alpha,12alpha-dihydroxy-5beta-cholanate)

Catalysed by SLC27A2, SLC27A5cytosolOne of 3 routes

1. glycodeoxycholate(in) + glutathione(in) + ATP + H2O = glycodeoxycholate(out) + glutathione(out) + ADP + phosphate + H(+)
2. S-sulfanylglutathione + O2 + H2O = sulfite + glutathione + 2 H(+)

Catalysed by ABCC4, ETHE1inner side of the membrane, outer side of the membraneOne of 4 routes

1. Glycodeoxycholate amidohydrolase
2. (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + glycine = N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + CoA + H(+)

Catalysed by GLYATL2cytosolOne of 2 routes

1. Glycodeoxycholate amidohydrolase
2. Hippurate (Benzoylglycinate) Formation

No catalyst recordedcytosol, mitochondrial matrixOne of 2 routes

1. glycodeoxycholate(in) + glutathione(in) + ATP + H2O = glycodeoxycholate(out) + glutathione(out) + ADP + phosphate + H(+)
2. glutathione + H2O = L-cysteinylglycine + L-glutamate

Catalysed by ABCC4, GGT3P, GGT1, GGT5 and 2 moreinner side of the membrane, outer side of the membraneOne of 2 routes

1. glycodeoxycholate(in) + glutathione(in) + ATP + H2O = glycodeoxycholate(out) + glutathione(out) + ADP + phosphate + H(+)
2. ubiquinone-10 + hydrogen sulfide + glutathione + H(+) = S-sulfanylglutathione + ubiquinol-10

Catalysed by ABCC4, SQORinner side of the membrane, outer side of the membrane

1. Glycodeoxycholate amidohydrolase
2. (2S)-2-aminobutanoate + glyoxylate = 2-oxobutanoate + glycine

Catalysed by AGXT2cytosol

1. glycodeoxycholate(in) + glutathione(in) + ATP + H2O = glycodeoxycholate(out) + glutathione(out) + ADP + phosphate + H(+)
2. (9S)-hydroperoxy-(10E,12Z)-octadecadienoate + 2 glutathione = (9S)-hydroxy-(10E,12Z)-octadecadienoate + glutathione disulfide + H2O

Catalysed by ABCC4, GPX1, GPX4inner side of the membrane, outer side of the membrane

1. glycodeoxycholate(in) + glutathione(in) + ATP + H2O = glycodeoxycholate(out) + glutathione(out) + ADP + phosphate + H(+)
2. (12R)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + 2 glutathione = (12R)-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + glutathione disulfide + H2O

Catalysed by ABCC4, GPX1, GPX2, GPX4inner side of the membrane, outer side of the membrane

1. Glycodeoxycholate amidohydrolase
2. tetradecanoyl-CoA + glycine = N-tetradecanoylglycine + CoA + H(+)

Catalysed by GLYATL2cytosol

1. Glycodeoxycholate amidohydrolase
2. eicosanoyl-CoA + glycine = N-eicosanoylglycinate + CoA + H(+)

Catalysed by BAATcytosol

1. Glycodeoxycholate amidohydrolase
2. docosanoyl-CoA + glycine = N-docosanoylglycine + CoA + H(+)

Catalysed by BAATcytosol

1. Glycodeoxycholate amidohydrolase
2. hexacosanoyl-CoA + glycine = N-hexacosanoylglycine + CoA + H(+)

Catalysed by BAATcytosol

1. glycodeoxycholate(in) + glutathione(in) + ATP + H2O = glycodeoxycholate(out) + glutathione(out) + ADP + phosphate + H(+)
2. (5S)-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + 2 glutathione = (5S)-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + glutathione disulfide + H2O

Catalysed by ABCC4, PTGES, MGST3, GPX1 and 3 moreinner side of the membrane, outer side of the membrane

1. glycodeoxycholate(in) + glutathione(in) + ATP + H2O = glycodeoxycholate(out) + glutathione(out) + ADP + phosphate + H(+)
2. (12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + 2 glutathione = (12S)-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + glutathione disulfide + H2O

Catalysed by ABCC4, GPX1, GPX4inner side of the membrane, outer side of the membrane

1. glycodeoxycholate(in) + glutathione(in) + ATP + H2O = glycodeoxycholate(out) + glutathione(out) + ADP + phosphate + H(+)
2. RX + glutathione = an S-substituted glutathione + a halide anion + H(+)

Catalysed by ABCC4, GSTT4, GSTA4, GSTZ1 and 20 moreinner side of the membrane, outer side of the membraneOne of 2 routes

1. glycodeoxycholate(in) + glutathione(in) + ATP + H2O = glycodeoxycholate(out) + glutathione(out) + ADP + phosphate + H(+)
2. (13S)-hydroperoxy-(9Z,11E)-octadecadienoate + 2 glutathione = (13S)-hydroxy-(9Z,11E)-octadecadienoate + glutathione disulfide + H2O

Catalysed by ABCC4, GPX1, GSTA1, GPX2 and 1 moreinner side of the membrane, outer side of the membrane

1. glycodeoxycholate(in) + glutathione(in) + ATP + H2O = glycodeoxycholate(out) + glutathione(out) + ADP + phosphate + H(+)
2. taurochenodeoxycholate(in) + glutathione(in) + ATP + H2O = taurochenodeoxycholate(out) + glutathione(out) + ADP + phosphate + H(+)

Catalysed by ABCC4inner side of the membrane, outer side of the membrane

1. Glycodeoxycholate amidohydrolase
2. transport of glycine and tryptophan (cytosol to extracellular)
3. beta-carboline hydrolysis

Catalysed by SLC7A5cytosol, extracellular space

1. Glycodeoxycholate amidohydrolase
2. bile acid-CoA: amino acid N-acyltransferase
3. Carnitine O-Palmitoyltransferase

Catalysed by BAAT, CPT1A, CPT1C,