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A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Proteins/UNIPROT:A0A087X1C5

CYP2D7

Protein·UNIPROT:A0A087X1C5Cytochrome P450 2D7

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May be responsible for the metabolism of many drugs and environmental chemicals that it oxidizes. It may be involved in the metabolism of codeine to morphine. However, another study could not confirm it..

Function from UniProtKB (A0A087X1C5), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

3 statements

3 statements · 2 reference databases · Subject: CYP2D7 · Sources: Rhea, UniProt

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an alcohol is metabolised by CYP2D7CompoundRhea RHEA:17149Inferred only
an organic molecule is metabolised by CYP2D7CompoundRhea RHEA:17149Inferred only
CYP2D7 requires the cofactor hemeCompoundUniProt A0A087X1C5Inferred only

Reactions

1 reaction

an organic molecule+reduced [NADPH--hemoprotein reductase]+dioxygenan alcohol+oxidized [NADPH--hemoprotein reductase]+water+hydron
Catalysed by CYP2D7 or CYP1A1 or CYP1A2 or CYP2E1 or CYP3A4 or CYP2C8 or CYP2C9 or CYP4B1 or CYP3A5 or CYP2A7 or

Other names

1 name

Resolves to: CYP2D7

Also called: Cytochrome P450 2D7

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and 13 more alternatives

Reaction pageReversibleBalance undeterminable

Rhea RHEA:17149CC BY 4.0Reference data