N-acetyl-alpha-D-glucosamine 1-phosphate

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

92 compounds within 3 steps: 2 in 1, 15 in 2, 75 in 3

Three steps

an alpha-D-Gal-(1->3)-[alpha-L-Fuc-(1->2)]-beta-D-Gal-(1->4)-beta-D-GlcNAc derivativeReach from here →
1. N-acetyl-alpha-D-glucosamine 1-phosphate + UTP + H(+) = UDP-N-acetyl-alpha-D-glucosamine + diphosphate
2. UDP-N-acetyl-alpha-D-glucosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-glucosamine(in) + UDP-alpha-D-galactose(out)
3. an alpha-L-Fuc-(1->2)-beta-D-Gal-(1->4)-beta-D-GlcNAc derivative + UDP-alpha-D-galactose = an alpha-D-Gal-(1->3)-[alpha-L-Fuc-(1->2)]-beta-D-Gal-(1->4)-beta-D-GlcNAc derivative + UDP + H(+)
Catalysed by UAP1, SLC35A2, ABOinner side of the membrane, outer side of the membrane
a 6-O-sulfo-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivativeReach from here →
1. N-acetyl-alpha-D-glucosamine 1-phosphate + UTP + H(+) = UDP-N-acetyl-alpha-D-glucosamine + diphosphate
2. a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + UDP-N-acetyl-alpha-D-glucosamine = an N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + UDP + H(+)
3. an N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + 3'-phosphoadenylyl sulfate = a 6-O-sulfo-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + adenosine 3',5'-bisphosphate + H(+)
Catalysed by UAP1, B3GNT8, B3GNT4, B3GNT2 and 2 more
an alpha-D-Gal-(1->3)-[alpha-L-Fuc-(1->2)]-beta-D-Gal-(1->3)-alpha-D-GalNAc derivativeReach from here →
1. N-acetyl-alpha-D-glucosamine 1-phosphate + UTP + H(+) = UDP-N-acetyl-alpha-D-glucosamine + diphosphate
2. UDP-N-acetyl-alpha-D-glucosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-glucosamine(in) + UDP-alpha-D-galactose(out)
3. an alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-alpha-D-GalNAc derivative + UDP-alpha-D-galactose = an alpha-D-Gal-(1->3)-[alpha-L-Fuc-(1->2)]-beta-D-Gal-(1->3)-alpha-D-GalNAc derivative + UDP + H(+)
Catalysed by UAP1, SLC35A2, ABOinner side of the membrane, outer side of the membrane
an alpha-D-Gal-(1->3)-[alpha-L-Fuc-(1->2)]-beta-D-Gal-(1->4)-beta-D-Glc derivativeReach from here →
1. N-acetyl-alpha-D-glucosamine 1-phosphate + UTP + H(+) = UDP-N-acetyl-alpha-D-glucosamine + diphosphate
2. UDP-N-acetyl-alpha-D-glucosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-glucosamine(in) + UDP-alpha-D-galactose(out)
3. an alpha-L-Fuc-(1->2)-beta-D-Gal-(1->4)-beta-D-Glc derivative + UDP-alpha-D-galactose = an alpha-D-Gal-(1->3)-[alpha-L-Fuc-(1->2)]-beta-D-Gal-(1->4)-beta-D-Glc derivative + UDP + H(+)
Catalysed by UAP1, SLC35A2, ABOinner side of the membrane, outer side of the membrane
an alpha-D-Gal-(1->3)-[alpha-L-Fuc-(1->2)]-beta-D-Gal-(1->3)-beta-D-GlcNAc derivativeReach from here →
1. N-acetyl-alpha-D-glucosamine 1-phosphate + UTP + H(+) = UDP-N-acetyl-alpha-D-glucosamine + diphosphate
2. UDP-N-acetyl-alpha-D-glucosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-glucosamine(in) + UDP-alpha-D-galactose(out)
3. an alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-beta-D-GlcNAc derivative + UDP-alpha-D-galactose = an alpha-D-Gal-(1->3)-[alpha-L-Fuc-(1->2)]-beta-D-Gal-(1->3)-beta-D-GlcNAc derivative + UDP + H(+)
Catalysed by UAP1, SLC35A2, ABOinner side of the membrane, outer side of the membrane
an alpha-D-Gal-(1->3)-[alpha-L-Fuc-(1->2)]-beta-D-Gal-(1->3)-beta-D-GalNAc derivativeReach from here →
1. N-acetyl-alpha-D-glucosamine 1-phosphate + UTP + H(+) = UDP-N-acetyl-alpha-D-glucosamine + diphosphate
2. UDP-N-acetyl-alpha-D-glucosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-glucosamine(in) + UDP-alpha-D-galactose(out)
3. an alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-beta-D-GalNAc derivative + UDP-alpha-D-galactose = an alpha-D-Gal-(1->3)-[alpha-L-Fuc-(1->2)]-beta-D-Gal-(1->3)-beta-D-GalNAc derivative + UDP + H(+)
Catalysed by UAP1, SLC35A2, ABOinner side of the membrane, outer side of the membrane
a ganglioside GA2 (d18:1(4E))Reach from here →
1. N-acetyl-alpha-D-glucosamine 1-phosphate + UTP + H(+) = UDP-N-acetyl-alpha-D-glucosamine + diphosphate
2. UDP-N-acetyl-alpha-D-glucosamine = UDP-N-acetyl-alpha-D-galactosamine
3. a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine = a ganglioside GA2 (d18:1(4E)) + UDP + H(+)
Catalysed by UAP1, GALE, B4GALNT1
a ganglioside GA1 (d18:1(4E))Reach from here →
1. N-acetyl-alpha-D-glucosamine 1-phosphate + UTP + H(+) = UDP-N-acetyl-alpha-D-glucosamine + diphosphate
2. UDP-N-acetyl-alpha-D-glucosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-glucosamine(in) + UDP-alpha-D-galactose(out)
3. a ganglioside GA2 (d18:1(4E)) + UDP-alpha-D-galactose = a ganglioside GA1 (d18:1(4E)) + UDP + H(+)
Catalysed by UAP1, SLC35A2, B3GALT4inner side of the membrane, outer side of the membrane
17alpha-hydroxypregnenoloneReach from here →
1. N-acetyl-alpha-D-glucosamine 1-phosphate = N-acetyl-D-glucosamine 6-phosphate
2. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
3. cytochrome P450 (17alpha-hydroxypregnenolone)
Catalysed by PGM3, CEMP1, AMDHD2, CYP17A1cytosol, endoplasmic reticulum
formic acidReach from here →
1. N-acetyl-alpha-D-glucosamine 1-phosphate = N-acetyl-D-glucosamine 6-phosphate
2. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
3. transport of acetate and formate (cytosol to extracellular)
Catalysed by PGM3, CEMP1, AMDHD2, SLC16A4 and 2 morecytosol, extracellular spaceOne of 2 routes
propionic acidReach from here →
1. N-acetyl-alpha-D-glucosamine 1-phosphate = N-acetyl-D-glucosamine 6-phosphate
2. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
3. transport of acetate and propanoate (cytosol to extracellular)
Catalysed by PGM3, CEMP1, AMDHD2, SLC16A4 and 3 morecytosol, extracellular spaceOne of 2 routes
butyric acidReach from here →
1. N-acetyl-alpha-D-glucosamine 1-phosphate = N-acetyl-D-glucosamine 6-phosphate
2. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
3. transport of acetate and butyrate (cytosol to extracellular)
Catalysed by PGM3, CEMP1, AMDHD2, SLC16A4 and 3 morecytosol, extracellular spaceOne of 2 routes
(S)-lactic acidReach from here →
1. N-acetyl-alpha-D-glucosamine 1-phosphate = N-acetyl-D-glucosamine 6-phosphate
2. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
3. transport of acetate and L-lactate (cytosol to extracellular)
Catalysed by PGM3, CEMP1, AMDHD2, SLC16A4 and 5 morecytosol, extracellular spaceOne of 2 routes
N-acetyl-beta-neuraminic acidReach from here →
1. N-acetyl-alpha-D-glucosamine 1-phosphate + UTP + H(+) = UDP-N-acetyl-alpha-D-glucosamine + diphosphate
2. UDP-N-acetyl-alpha-D-glucosamine + H2O = aldehydo-N-acetyl-D-mannosamine + UDP + H(+)
3. N-Acetylneuraminate pyruvate-lyase (N-acetyl-D-mannosamine-forming)
Catalysed by UAP1, GNE, NPLcytosol
N-(acetyl)-sphing-4-enineReach from here →
1. N-acetyl-alpha-D-glucosamine 1-phosphate = N-acetyl-D-glucosamine 6-phosphate
2. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
3. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
Catalysed by PGM3, CEMP1, AMDHD2, ASAH1cytosol
N-acetyl-D-glucosamineReach from here →
1. N-acetyl-alpha-D-glucosamine 1-phosphate + UTP + H(+) = UDP-N-acetyl-alpha-D-glucosamine + diphosphate
2. UDP-N-acetyl-alpha-D-glucosamine + H2O = aldehydo-N-acetyl-D-mannosamine + UDP + H(+)
3. N-acetyl-D-glucosamine 2-epimerase
Catalysed by UAP1, GNE, RENBPcytosol
an isogloboside iGb3Cer (d18:1(4E))Reach from here →
1. N-acetyl-alpha-D-glucosamine 1-phosphate + UTP + H(+) = UDP-N-acetyl-alpha-D-glucosamine + diphosphate
2. UDP-N-acetyl-alpha-D-glucosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-glucosamine(in) + UDP-alpha-D-galactose(out)
3. a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP-alpha-D-galactose = an isogloboside iGb3Cer (d18:1(4E)) + UDP + H(+)
Catalysed by UAP1, SLC35A2, A3GALT2inner side of the membrane, outer side of the membrane
beta-D-fructose 6-phosphateReach from here →
1. N-acetyl-alpha-D-glucosamine 1-phosphate = N-acetyl-D-glucosamine 6-phosphate
2. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
3. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
Catalysed by PGM3, CEMP1, AMDHD2, GNPDA1 and 1 morecytosol
a 6-(alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositolReach from here →
1. N-acetyl-alpha-D-glucosamine 1-phosphate + UTP + H(+) = UDP-N-acetyl-alpha-D-glucosamine + diphosphate
2. a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + UDP-N-acetyl-alpha-D-glucosamine = a 6-(N-acetyl-alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol + UDP + H(+)
3. phosphatidylinositol glycan anchor biosynthesis class L
Catalysed by UAP1, PIGA, PIGLendoplasmic reticulumOne of 3 routes
N-acetylputrescineReach from here →
1. N-acetyl-alpha-D-glucosamine 1-phosphate = N-acetyl-D-glucosamine 6-phosphate
2. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
3. N-acetylputrescine + H2O = putrescine + acetate
Catalysed by PGM3, CEMP1, AMDHD2, HDAC10cytosol
alpha-D-galactose 1-phosphateReach from here →
1. N-acetyl-alpha-D-glucosamine 1-phosphate + UTP + H(+) = UDP-N-acetyl-alpha-D-glucosamine + diphosphate
2. UDP-N-acetyl-alpha-D-glucosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-glucosamine(in) + UDP-alpha-D-galactose(out)
3. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
Catalysed by UAP1, SLC35A2, GALTinner side of the membrane, outer side of the membraneOne of 2 routes
N(8)-acetylspermidineReach from here →
1. N-acetyl-alpha-D-glucosamine 1-phosphate = N-acetyl-D-glucosamine 6-phosphate
2. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
3. N(8)-acetylspermidine + H2O = spermidine + acetate
Catalysed by PGM3, CEMP1, AMDHD2, HDAC10cytosol
aldehydo-N-acetyl-D-mannosamine 6-phosphateReach from here →
1. N-acetyl-alpha-D-glucosamine 1-phosphate + UTP + H(+) = UDP-N-acetyl-alpha-D-glucosamine + diphosphate
2. UDP-N-acetyl-alpha-D-glucosamine + H2O = aldehydo-N-acetyl-D-mannosamine + UDP + H(+)
3. ATP:N-acyl-D-mannosamine 6-phosphotransferase
Catalysed by UAP1, GNEcytosolOne of 2 routes
an N-acetyl-L-cysteine-S-conjugateReach from here →
1. N-acetyl-alpha-D-glucosamine 1-phosphate = N-acetyl-D-glucosamine 6-phosphate
2. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
3. an N-acetyl-L-cysteine-S-conjugate + H2O = an S-substituted L-cysteine + acetate
Catalysed by PGM3, CEMP1, AMDHD2, ACY3cytosol
UDP-alpha-D-glucoseReach from here →
1. N-acetyl-alpha-D-glucosamine 1-phosphate + UTP + H(+) = UDP-N-acetyl-alpha-D-glucosamine + diphosphate
2. UDP-N-acetyl-alpha-D-glucosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-glucosamine(in) + UDP-alpha-D-galactose(out)
3. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
Catalysed by UAP1, SLC35A2, GALTinner side of the membrane, outer side of the membraneOne of 4 routes
beta-D-galactosyl-(1->4)-N-acetyl-D-glucosamineReach from here →
1. N-acetyl-alpha-D-glucosamine 1-phosphate + UTP + H(+) = UDP-N-acetyl-alpha-D-glucosamine + diphosphate
2. UDP-N-acetyl-alpha-D-glucosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-glucosamine(in) + UDP-alpha-D-galactose(out)
3. N-acetyl-D-glucosamine + UDP-alpha-D-galactose = beta-D-galactosyl-(1->4)-N-acetyl-D-glucosamine + UDP + H(+)
Catalysed by UAP1, SLC35A2, B4GALT3, B4GALT4 and 2 moreinner side of the membrane, outer side of the membrane
a globoside GalGb4Cer (d18:1(4E))Reach from here →
1. N-acetyl-alpha-D-glucosamine 1-phosphate + UTP + H(+) = UDP-N-acetyl-alpha-D-glucosamine + diphosphate
2. UDP-N-acetyl-alpha-D-glucosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-glucosamine(in) + UDP-alpha-D-galactose(out)
3. a globoside Gb4Cer (d18:1(4E)) + UDP-alpha-D-galactose = a globoside GalGb4Cer (d18:1(4E)) + UDP + H(+)
Catalysed by UAP1, SLC35A2, B3GALT5inner side of the membrane, outer side of the membrane
a ganglioside GM2 (d18:1(4E))Reach from here →
1. N-acetyl-alpha-D-glucosamine 1-phosphate + UTP + H(+) = UDP-N-acetyl-alpha-D-glucosamine + diphosphate
2. UDP-N-acetyl-alpha-D-glucosamine = UDP-N-acetyl-alpha-D-galactosamine
3. a ganglioside GM3 (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine = a ganglioside GM2 (d18:1(4E)) + UDP + H(+)
Catalysed by UAP1, GALE, B4GALNT1
a ganglioside GM1 (d18:1(4E))Reach from here →
1. N-acetyl-alpha-D-glucosamine 1-phosphate + UTP + H(+) = UDP-N-acetyl-alpha-D-glucosamine + diphosphate
2. UDP-N-acetyl-alpha-D-glucosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-glucosamine(in) + UDP-alpha-D-galactose(out)
3. a ganglioside GM2 (d18:1(4E)) + UDP-alpha-D-galactose = a ganglioside GM1 (d18:1(4E)) + UDP + H(+)
Catalysed by UAP1, SLC35A2, B3GALT4inner side of the membrane, outer side of the membrane
a ganglioside GD2 (d18:1(4E))Reach from here →
1. N-acetyl-alpha-D-glucosamine 1-phosphate + UTP + H(+) = UDP-N-acetyl-alpha-D-glucosamine + diphosphate
2. UDP-N-acetyl-alpha-D-glucosamine = UDP-N-acetyl-alpha-D-galactosamine
3. a ganglioside GD3 (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine = a ganglioside GD2 (d18:1(4E)) + UDP + H(+)
Catalysed by UAP1, GALE, B4GALNT1
a neolactoside IV(3)-beta-[Gal-beta-(1->3)-GlcNAc]-nLc4Cer(d18:1(4E))Reach from here →
1. N-acetyl-alpha-D-glucosamine 1-phosphate + UTP + H(+) = UDP-N-acetyl-alpha-D-glucosamine + diphosphate
2. a neolactoside nLc4Cer(d18:1(4E)) + UDP-N-acetyl-alpha-D-glucosamine = a neolactoside IV(3)-beta-GlcNAc-nLc4Cer(d18:1(4E)) + UDP + H(+)
3. a neolactoside IV(3)-beta-GlcNAc-nLc4Cer(d18:1(4E)) + UDP-alpha-D-galactose = a neolactoside IV(3)-beta-[Gal-beta-(1->3)-GlcNAc]-nLc4Cer(d18:1(4E)) + UDP + H(+)
Catalysed by UAP1, B3GNT5, B3GALT2One of 2 routes
a beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramideReach from here →
1. N-acetyl-alpha-D-glucosamine 1-phosphate + UTP + H(+) = UDP-N-acetyl-alpha-D-glucosamine + diphosphate
2. UDP-N-acetyl-alpha-D-glucosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-glucosamine(in) + UDP-alpha-D-galactose(out)
3. a beta-D-glucosylceramide + UDP-alpha-D-galactose = a beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + UDP + H(+)
Catalysed by UAP1, SLC35A2, B4GALT3, B4GALT1inner side of the membrane, outer side of the membrane
a ganglioside GM2Reach from here →
1. N-acetyl-alpha-D-glucosamine 1-phosphate + UTP + H(+) = UDP-N-acetyl-alpha-D-glucosamine + diphosphate
2. UDP-N-acetyl-alpha-D-glucosamine = UDP-N-acetyl-alpha-D-galactosamine
3. a ganglioside GM3 + UDP-N-acetyl-alpha-D-galactosamine = a ganglioside GM2 + UDP + H(+)
Catalysed by UAP1, GALE, B4GALNT1
a ganglioside GD2Reach from here →
1. N-acetyl-alpha-D-glucosamine 1-phosphate + UTP + H(+) = UDP-N-acetyl-alpha-D-glucosamine + diphosphate
2. UDP-N-acetyl-alpha-D-glucosamine = UDP-N-acetyl-alpha-D-galactosamine
3. a ganglioside GD3 + UDP-N-acetyl-alpha-D-galactosamine = a ganglioside GD2 + UDP + H(+)
Catalysed by UAP1, GALE, B4GALNT1
a ganglioside GM1Reach from here →
1. N-acetyl-alpha-D-glucosamine 1-phosphate + UTP + H(+) = UDP-N-acetyl-alpha-D-glucosamine + diphosphate
2. UDP-N-acetyl-alpha-D-glucosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-glucosamine(in) + UDP-alpha-D-galactose(out)
3. a ganglioside GM2 + UDP-alpha-D-galactose = a ganglioside GM1 + UDP + H(+)
Catalysed by UAP1, SLC35A2, B3GALT4inner side of the membrane, outer side of the membrane
a ganglioside GalNAc-GD1aReach from here →
1. N-acetyl-alpha-D-glucosamine 1-phosphate + UTP + H(+) = UDP-N-acetyl-alpha-D-glucosamine + diphosphate
2. UDP-N-acetyl-alpha-D-glucosamine = UDP-N-acetyl-alpha-D-galactosamine
3. a ganglioside GD1a + UDP-N-acetyl-alpha-D-galactosamine = a ganglioside GalNAc-GD1a + UDP + H(+)
Catalysed by UAP1, GALE, B4GALNT1
N-(2-hydroxy-hexanoyl)-beta-D-galactosyl-sphing-4-enineReach from here →
1. N-acetyl-alpha-D-glucosamine 1-phosphate + UTP + H(+) = UDP-N-acetyl-alpha-D-glucosamine + diphosphate
2. UDP-N-acetyl-alpha-D-glucosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-glucosamine(in) + UDP-alpha-D-galactose(out)
3. N-(2-hydroxy-hexanoyl)-sphing-4-enine + UDP-alpha-D-galactose = N-(2-hydroxy-hexanoyl)-beta-D-galactosyl-sphing-4-enine + UDP + H(+)
Catalysed by UAP1, SLC35A2, UGT8inner side of the membrane, outer side of the membrane
N-(2-hydroxyhexanoyl)-beta-D-galactosylsphinganineReach from here →
1. N-acetyl-alpha-D-glucosamine 1-phosphate + UTP + H(+) = UDP-N-acetyl-alpha-D-glucosamine + diphosphate
2. UDP-N-acetyl-alpha-D-glucosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-glucosamine(in) + UDP-alpha-D-galactose(out)
3. N-(2-hydroxy-hexanoyl)-sphinganine + UDP-alpha-D-galactose = N-(2-hydroxyhexanoyl)-beta-D-galactosylsphinganine + UDP + H(+)
Catalysed by UAP1, SLC35A2, UGT8inner side of the membrane, outer side of the membrane
a ganglioside GD1b (d18:1(4E))Reach from here →
1. N-acetyl-alpha-D-glucosamine 1-phosphate + UTP + H(+) = UDP-N-acetyl-alpha-D-glucosamine + diphosphate
2. UDP-N-acetyl-alpha-D-glucosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-glucosamine(in) + UDP-alpha-D-galactose(out)
3. a ganglioside GD2 (d18:1(4E)) + UDP-alpha-D-galactose = a ganglioside GD1b (d18:1(4E)) + UDP + H(+)
Catalysed by UAP1, SLC35A2, B3GALT4inner side of the membrane, outer side of the membrane
a globoside Gb3CerReach from here →
1. N-acetyl-alpha-D-glucosamine 1-phosphate + UTP + H(+) = UDP-N-acetyl-alpha-D-glucosamine + diphosphate
2. UDP-N-acetyl-alpha-D-glucosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-glucosamine(in) + UDP-alpha-D-galactose(out)
3. a beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + UDP-alpha-D-galactose = a globoside Gb3Cer + UDP + H(+)
Catalysed by UAP1, SLC35A2, A4GALTinner side of the membrane, outer side of the membrane
a ganglioside GA2Reach from here →
1. N-acetyl-alpha-D-glucosamine 1-phosphate + UTP + H(+) = UDP-N-acetyl-alpha-D-glucosamine + diphosphate
2. UDP-N-acetyl-alpha-D-glucosamine = UDP-N-acetyl-alpha-D-galactosamine
3. a beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + UDP-N-acetyl-alpha-D-galactosamine = a ganglioside GA2 + UDP + H(+)
Catalysed by UAP1, GALE, B4GALNT1
a neolactoside nLc6CerReach from here →
1. N-acetyl-alpha-D-glucosamine 1-phosphate + UTP + H(+) = UDP-N-acetyl-alpha-D-glucosamine + diphosphate
2. UDP-N-acetyl-alpha-D-glucosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-glucosamine(in) + UDP-alpha-D-galactose(out)
3. a neolactoside IV(3)-beta-GlcNAc-nLc4Cer + UDP-alpha-D-galactose = a neolactoside nLc6Cer + UDP + H(+)
Catalysed by UAP1, SLC35A2, B4GALT3, B4GALT1inner side of the membrane, outer side of the membrane