Compound
a ganglioside GD1b (d18:1(4E))
An anionic ganglioside obtained by deprotonation of the neuraminosyl carboxy groups of β-Gal-(1→3)-β-GalNAc-(1→4)-[α-Neu5Ac-(2→8)-α-Neu5Ac-(2→3)]-β-Gal-(1→4)-β-Glc-(1↔1')-Cer; major species at pH 7.3.
Definition from ChEBI (CHEBI:87785), read 2026-09-23. CC BY 4.0.
Structure
- Class
- Organic compound, anion
- Formula
- C67H111N4O39R
- Mass
- 1596.604 g/mol
- Charge
- -2
- SMILES
- *C(=O)N[C@@H](CO[C@@H]1O[C@H](CO)[C@@H](O[C@@H]2O[C@H](CO)[C@H](O[C@@H]3O[C@H](CO)[C@H](O)[C@H](O[C@@H]4O[C@H](CO)[C@H](O)[C@H](O)[C@H]4O)[C@H]3NC(C)=O)[C@H](O[C@]3(C(=O)[O-])C[C@H](O)[C@@H](NC(C)=O)[C@]([H])([C@H](O)[C@@H](CO)O[C@]4(C(=O)[O-])C[C@H](O)[C@@H](NC(C)=O)[C@]([H])([C@H](O)[C@H](O)CO)O4)O3)[C@H]2O)[C@H](O)[C@H]1O)[C@H](O)/C=C/CCCCCCCCCCCCC
- Look it up
- ChEBI
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
7 entities
7 entities reached.
0 reported hops7 assembled from the scaffold
- ST3GAL2ProteinUNIPROT:Q16842substrate ofInferred only96 paths32 endpoints
- ST3GAL4ProteinUNIPROT:Q11206substrate ofInferred only76 paths38 endpoints
- ST3GAL1ProteinUNIPROT:Q11201substrate ofInferred only56 paths28 endpoints
- NEU3ProteinUNIPROT:Q9UQ49substrate ofInferred only28 paths14 endpoints
- NEU2ProteinUNIPROT:Q9Y3R4substrate ofInferred only14 paths14 endpoints
- B3GALT4ProteinUNIPROT:O96024substrate ofInferred only13 paths13 endpoints
- GLB1ProteinUNIPROT:P16278substrate ofInferred only7 paths7 endpoints
What the reference databases state
Statements
12 statements
12 statements · 2 reference databases · Subject: a ganglioside GD1b (d18:1(4E)) · Sources: Human-GEM, Rhea
- a ganglioside GD1b (d18:1(4E)) is a substrate of B3GALT4ProteinRhea RHEA:47568Inferred only
- a ganglioside GD1b (d18:1(4E)) is a substrate of GLB1ProteinHuman-GEM MAR12038Inferred only
- a ganglioside GD1b (d18:1(4E)) is a substrate of NEU2ProteinHuman-GEM MAR12067Inferred only
- a ganglioside GD1b (d18:1(4E)) is a substrate of NEU3ProteinRhea RHEA:48064Inferred only
- a ganglioside GD1b (d18:1(4E)) is a substrate of NEU3ProteinHuman-GEM MAR12072Inferred only
- a ganglioside GD1b (d18:1(4E)) is a substrate of ST3GAL1ProteinHuman-GEM MAR00844Inferred only
- a ganglioside GD1b (d18:1(4E)) is a substrate of ST3GAL1ProteinHuman-GEM MAR08189Inferred only
- a ganglioside GD1b (d18:1(4E)) is a substrate of ST3GAL2ProteinHuman-GEM MAR08189Inferred only
- a ganglioside GD1b (d18:1(4E)) is a substrate of ST3GAL2ProteinHuman-GEM MAR00844Inferred only
- a ganglioside GD1b (d18:1(4E)) is a substrate of ST3GAL2ProteinRhea RHEA:47572Inferred only
- a ganglioside GD1b (d18:1(4E)) is a substrate of ST3GAL4ProteinHuman-GEM MAR00844Inferred only
- a ganglioside GD1b (d18:1(4E)) is a substrate of ST3GAL4ProteinHuman-GEM MAR08189Inferred only
Reactions
20 reactions
a ganglioside GD2 (d18:1(4E))+CHEBI:67119a ganglioside GD1b (d18:1(4E))+proton+UDP
Catalysed by B3GALT4
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.62GO:0005829
Human-GEM MAR00843CC BY 4.0Reference data
CMP-N-acetyl-beta-neuraminate+a ganglioside GD1b (d18:1(4E))cytidine 5'-monophosphate+a ganglioside GT1b (d18:1(4E))+proton
Catalysed by ST3GAL1 or ST3GAL4 or ST3GAL2
Reaction pageLeft to rightBalance undeterminableEC 2.4.3.4GO:0005829
Human-GEM MAR00844CC BY 4.0Reference data
a ganglioside GT1b (d18:1(4E))+watera ganglioside GD1b (d18:1(4E))+N-acetyl-beta-neuraminic acid
Catalysed by NEU2 or NEU3 or NEU4 or NEU1
Reaction pageLeft to rightBalance undeterminableEC 3.2.1.18GO:0005829
Human-GEM MAR00845CC BY 4.0Reference data
CMP-N-acetyl-beta-neuraminate+a ganglioside GM1 (d18:1(4E))cytidine 5'-monophosphate+a ganglioside GD1b (d18:1(4E))+proton
Catalysed by ST8SIA1
Reaction pageLeft to rightBalance undeterminableEC 2.4.3.8GO:0005829
Human-GEM MAR00852CC BY 4.0Reference data
a ganglioside GD2 (d18:1(4E))+CHEBI:67119a ganglioside GD1b (d18:1(4E))+proton+UDP
Catalysed by B3GALT4
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.62GO:0005794
Human-GEM MAR08186CC BY 4.0Reference data
CMP-N-acetyl-beta-neuraminate+a ganglioside GD1b (d18:1(4E))cytidine 5'-monophosphate+a ganglioside GT1b (d18:1(4E))+proton
Catalysed by ST3GAL1 or ST3GAL4 or ST3GAL2
Reaction pageLeft to rightBalance undeterminableEC 2.4.3.4GO:0005794
Human-GEM MAR08189CC BY 4.0Reference data
a ganglioside GD1b (d18:1(4E))+wateralpha-D-galactose+a ganglioside GD2 (d18:1(4E))
Catalysed by GLB1
Reaction pageLeft to rightBalance undeterminableEC 3.2.1.23GO:0005764
Human-GEM MAR12038CC BY 4.0Reference data
a ganglioside GD1b (d18:1(4E))+waterN-acetyl-beta-neuraminic acid+a ganglioside GM1 (d18:1(4E))
Catalysed by NEU2
Reaction pageLeft to rightBalance undeterminableEC 3.2.1.18GO:0005829
Human-GEM MAR12067CC BY 4.0Reference data
a ganglioside GD1b (d18:1(4E))+waterN-acetyl-beta-neuraminic acid+a ganglioside GM1 (d18:1(4E))
Catalysed by NEU3
Reaction pageLeft to rightBalance undeterminableEC 3.2.1.18GO:0005615
Human-GEM MAR12072CC BY 4.0Reference data
a ganglioside GT1b (d18:1(4E))+watera ganglioside GD1b (d18:1(4E))+N-acetyl-beta-neuraminic acid
Catalysed by NEU3
Reaction pageLeft to rightBalance undeterminableEC 3.2.1.18GO:0005615
Human-GEM MAR12073CC BY 4.0Reference data
a ganglioside GD1b (d18:1(4E))a ganglioside GD1b (d18:1(4E))
Reaction pageReversibleBalance undeterminableGO:0005829, GO:0005764
Human-GEM MAR12121CC BY 4.0Reference data
a ganglioside GD1b (d18:1(4E))
Reaction pageReversibleBalance undeterminableGO:0005615
Human-GEM MAR12138CC BY 4.0Reference data
Other names
2 names
Resolves to: a ganglioside GD1b (d18:1(4E))
- Also called
- Ganglioside GD1b (d18:1(4E))GD1b(d18:1(4E))