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Proteins/UNIPROT:Q8N5Z5
Substrate-adapter for CUL3-RING ubiquitin ligase complexes which mediates the ubiquitination and subsequent proteasomal degradation of TCHP, a protein involved in ciliogenesis down-regulation. Thereby, positively regulates ciliogenesis, playing a crucial role in the initial steps of axoneme extension. May also play a role in endoplasmic reticulum calcium ion homeostasis..
Function from UniProtKB (Q8N5Z5), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
2 rows
32 statements
32 statements · 2 reference databases · Subject: KCTD17 · Sources: gene ontology, Hetionet
1 name
Resolves to: KCTD17