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Proteins/UNIPROT:Q14296
Phosphorylates the splicing regulator TIA1, thereby promoting the inclusion of FAS exon 6, which leads to an mRNA encoding a pro-apoptotic form of the receptor..
[Isoform 4]: Required for the biogenesis of some mitochondrial-encoded mRNAs, specifically stabilizes ND6 (NADH dehydrogenase complex subunit 6) mRNA, and regulates its levels..
Function from UniProtKB (Q14296), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
26 statements
26 statements · 2 reference databases · Subject: FASTK · Sources: gene ontology, Hetionet
4 reactions
L-seryl-[Fas-activated protein]+ATP(4-)O-phospho-L-seryl-[Fas-activated protein]+ADP(3-)+hydron
Catalysed by FASTK
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:15881CC BY 4.0Reference data
L-seryl-[protein]+ATP(4-)O-phospho-L-seryl-[protein]+ADP(3-)+hydron
1 name
Resolves to: FASTK
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:17989CC BY 4.0Reference data
L-threonyl-[protein]+ATP(4-)O-phospho-L-threonyl-[protein]+ADP(3-)+hydron
Catalysed by SGK1 or CDC7 or PLK4 or STK25 or CIT or RIOK3 or MAP2K7 or CHEK1 or IKBKB or CASK or AURKA or GAK and 341 more alternatives
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:46608CC BY 4.0Reference data
L-threonyl-[Fas-activated protein]+ATP(4-)O-phospho-L-threonyl-[Fas-activated protein]+ADP(3-)+hydron
Catalysed by FASTK
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:53920CC BY 4.0Reference data