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Proteins/UNIPROT:P14770

GP9

Protein·UNIPROT:P14770

Open in the graph

The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis. GP-IX may provide for membrane insertion and orientation of GP-Ib.

Function from UniProtKB (P14770), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

GenCC submitters' classifications

1 row

Bernard-Soulier syndrome has a germline basis in GP9DiseaseGenCC HGNC:4444|MONDO:0009276Inferred only

Statements

34 statements

34 statements · 4 reference databases · Subject: GP9 · Sources: gene ontology, Hetionet, Reactome, WikiPathways

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AADACL2 covaries with GP9ProteinHetionet hetionet:covaries:2815-344752Inferred only
GP9 covaries with ACTL10ProteinHetionet hetionet:covaries:170487-2815Inferred only
GP9 covaries with ATP13A2ProteinHetionet hetionet:covaries:23400-2815Inferred only
GP9 covaries with BCRProteinHetionet hetionet:covaries:2815-613Inferred only
FBXO10 covaries with GP9ProteinHetionet hetionet:covaries:26267-2815Inferred only
GP9 covaries with KRTAP1-3ProteinHetionet hetionet:covaries:2815-81850Inferred only
GP9 covaries with P2RY2ProteinHetionet hetionet:covaries:2815-5029Inferred only
GP9 covaries with PLD3ProteinHetionet hetionet:covaries:23646-2815Inferred only
GP9 covaries with POLR2MProteinHetionet hetionet:covaries:2815-81488Inferred only
TREX2 covaries with GP9ProteinHetionet hetionet:covaries:11219-2815Inferred only
GP9 covaries with UTP6ProteinHetionet hetionet:covaries:2815-55813Inferred only
GP9 interacts with APPBP2ProteinHetionet hetionet:interacts:10513-2815Inferred only

Show the remaining 22

CRK interacts with GP9ProteinHetionet hetionet:interacts:1398-2815Inferred only
GP1BB interacts with GP9ProteinHetionet hetionet:interacts:2812-2815Inferred only
GP9 participates in 22q11 2 copy number variation syndromePathwayWikiPathways WP4657Inferred only
GP9 participates in Amplification and propagation of coagulation cascadePathwayReactome R-HSA-9769743Inferred only
GP9 participates in Coagulation pathwayPathwayReactome R-HSA-9769740Inferred only
GP9 participates in Defective binding of VWF variant to GPIb:IX:VPathwayReactome R-HSA-9846298Inferred only
GP9 participates in Defective F9 activationPathwayReactome R-HSA-9673221Inferred only
GP9 participates in Defective factor IX causes hemophilia BPathwayReactome R-HSA-9668250Inferred only
GP9 participates in Defects of Coagulation cascadePathwayReactome R-HSA-9769726Inferred only
GP9 participates in Defects of platelet adhesion to exposed collagenPathwayReactome R-HSA-9823587Inferred only
GP9 participates in DiseasePathwayReactome R-HSA-1643685Inferred only
GP9 participates in Diseases of hemostasisPathwayReactome R-HSA-9671793Inferred only
GP9 participates in Enhanced binding of GP1BA variant to VWF multimer:collagenPathwayReactome R-HSA-9845620Inferred only
GP9 participates in FXIIa, PKa-dependent activation of coagulation pathwayPathwayReactome R-HSA-9935598Inferred only
GP9 participates in GP1b-IX-V activation signallingPathwayReactome R-HSA-430116Inferred only
GP9 participates in Hematopoietic stem cell differentiationPathwayWikiPathways WP2849Inferred only
GP9 participates in HemostasisPathwayReactome R-HSA-109582Inferred only
GP9 participates in Platelet activation, signaling and aggregationPathwayReactome R-HSA-76002Inferred only
GP9 participates in Platelet Adhesion to exposed collagenPathwayReactome R-HSA-75892Inferred only
GP9 participates in Platelet Aggregation (Plug Formation)PathwayReactome R-HSA-76009Inferred only
GP9 participates in Regulation of clotting cascadePathwayReactome R-HSA-9769739Inferred only
GP9 regulates positive regulation of platelet activationBiological processgene ontology P14770|GO:0010572Inferred only

Other names

4 names

Resolves to: GP9

Also called: CD antigen CD42aGlycoprotein 9GP-IXGPIX

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