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Proteins/UNIPROT:P31994
Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.
Function from UniProtKB (P31994), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
53 statements
53 statements · 4 reference databases · Subject: FCGR2B · Sources: gene ontology, Hetionet, Reactome, WikiPathways
9 names
Resolves to: FCGR2B