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Proteins/UNIPROT:P42356
Acts on phosphatidylinositol (PtdIns) in the first committed step in the production of the second messenger inositol-1,4,5,-trisphosphate..
Function from UniProtKB (P42356), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
103 statements
103 statements · 6 reference databases · Subject: PI4KA · Sources: Bgee, Hetionet, Human-GEM, Reactome, Rhea, WikiPathways
6 reactions
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate)+ATPADP+proton+MAM02736g
Reaction pageLeft to rightBalance undeterminableEC 2.7.1.67Golgi apparatus
Human-GEM MAR03300CC BY 4.0Reference data
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate)+ATPADP+proton+MAM02736m
Catalysed by
6 names
Resolves to: PI4KA
Reaction pageLeft to rightBalance undeterminableEC 2.7.1.67mitochondrial matrix
Human-GEM MAR03303CC BY 4.0Reference data
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate)+ATPADP+proton+MAM02736r
Reaction pageLeft to rightBalance undeterminableEC 2.7.1.137endoplasmic reticulum
Human-GEM MAR03308CC BY 4.0Reference data
ATP+1-phosphatidyl-1D-myo-inositola 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate)+ADP+proton
Catalysed by PI4K2B or PI4KB or PI4K2A or PI4KA
Reaction pageLeft to rightBalance undeterminableEC 2.7.1.67cytosol
Human-GEM MAR06546CC BY 4.0Reference data
ATP+1-phosphatidyl-1D-myo-inositola 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate)+ADP+proton
Catalysed by PI4K2B or PI4KB or PI4K2A or PI4KA
Reaction pageLeft to rightBalance undeterminableEC 2.7.1.67nucleus
Human-GEM MAR08830CC BY 4.0Reference data
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)+ATP(4-)a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate)+ADP(3-)+hydron
Catalysed by PI4KA or PI4K2B or PI4K2A or PI4KB
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:19877CC BY 4.0Reference data