a 1,2-diacyl-sn-glycero-3-phosphocholine

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

612 compounds within 3 steps: 28 in 1, 110 in 2, 474 in 3

Two steps

N-hexadecanoylsphinganineReach from here →
1. a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = phosphocholine + a 1,2-diacyl-sn-glycerol + H(+)
2. N-hexadecanoylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = N-hexadecanoyl-sphinganine-1-phosphocholine + a 1,2-diacyl-sn-glycerol
Catalysed by SMPD1, SGMS1, SGMS2One of 2 routes
(6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoAReach from here →
1. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
2. acyl-CoA pool formation and breakdown
Catalysed by LPGAT1cytosol
1,2-dihexadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. an N-acylsphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sphingomyelin + a 1,2-diacyl-sn-glycerol
2. 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + an N-acylsphing-4-enine = 1,2-dihexadecanoyl-sn-glycerol + a sphingomyelin
Catalysed by SGMS1, SGMS2
(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoAReach from here →
1. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
2. acyl-CoA pool formation and breakdown
Catalysed by LPGAT1cytosol
(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoAReach from here →
1. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
2. acyl-CoA pool formation and breakdown
Catalysed by LPGAT1cytosol
(9Z,12Z,15Z)-octadecatrienoyl-CoAReach from here →
1. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
2. acyl-CoA pool formation and breakdown
Catalysed by LPGAT1cytosol
(13Z)-docosenoyl-CoAReach from here →
1. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
2. acyl-CoA pool formation and breakdown
Catalysed by LPGAT1cytosol
(11Z)-eicosenoyl-CoAReach from here →
1. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
2. acyl-CoA pool formation and breakdown
Catalysed by LPGAT1cytosol
(9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoAReach from here →
1. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
2. acyl-CoA pool formation and breakdown
Catalysed by LPGAT1cytosol
(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoAReach from here →
1. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
2. acyl-CoA pool formation and breakdown
Catalysed by LPGAT1cytosol
(15Z)-tetracosenoyl-CoAReach from here →
1. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
2. acyl-CoA pool formation and breakdown
Catalysed by LPGAT1cytosol
(17Z)-hexacosenoyl-CoAReach from here →
1. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
2. acyl-CoA pool formation and breakdown
Catalysed by LPGAT1cytosol
(8Z,11Z,14Z)-eicosatrienoyl-CoAReach from here →
1. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
2. acyl-CoA pool formation and breakdown
Catalysed by LPGAT1cytosol
(8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoAReach from here →
1. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
2. acyl-CoA pool formation and breakdown
Catalysed by LPGAT1cytosol
(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoAReach from here →
1. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
2. acyl-CoA pool formation and breakdown
Catalysed by LPGAT1cytosol
heptadecanoyl-CoAReach from here →
1. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
2. acyl-CoA pool formation and breakdown
Catalysed by LPGAT1cytosol
(9Z)-heptadecenoyl-CoAReach from here →
1. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
2. acyl-CoA pool formation and breakdown
Catalysed by LPGAT1cytosol
(11Z,14Z,17Z)-eicosatrienoyl-CoAReach from here →
1. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
2. acyl-CoA pool formation and breakdown
Catalysed by LPGAT1cytosol
1-acyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholineReach from here →
1. a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1-acyl-sn-glycero-3-phosphocholine + a fatty acid + H(+)
2. (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + a 1-acyl-sn-glycero-3-phosphocholine = 1-acyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + CoA
Catalysed by PLA2G10, PLA2G6, PLA2G1B, PLA2G4B and 27 more
nonadecanoyl-CoAReach from here →
1. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
2. acyl-CoA pool formation and breakdown
Catalysed by LPGAT1cytosol
1-acyl-2-hexadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1-acyl-sn-glycero-3-phosphocholine + a fatty acid + H(+)
2. a 1-acyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1-acyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by PLA2G10, PLA2G6, PLA2G1B, PLA2G4B and 28 more
a 2,3-diacyl-sn-glycerolReach from here →
1. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
2. a 2-acylglycerol + an acyl-CoA = a 2,3-diacyl-sn-glycerol + CoA
Catalysed by LPGAT1, MOGAT2, MOGAT1
2-hexadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
2. 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + a 2-acyl-sn-glycero-3-phosphocholine = a 1-hexadecanoyl-2-acyl-sn-glycero-3-phosphocholine + 2-hexadecanoyl-sn-glycero-3-phosphocholine
Catalysed by LPGAT1, PLAAT1
(4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoAReach from here →
1. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
2. acyl-CoA pool formation and breakdown
Catalysed by LPGAT1cytosol
(11Z,14Z)-eicosadienoyl-CoAReach from here →
1. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
2. acyl-CoA pool formation and breakdown
Catalysed by LPGAT1cytosol
(13Z)-eicosenoyl-CoAReach from here →
1. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
2. acyl-CoA pool formation and breakdown
Catalysed by LPGAT1cytosol
a 1,3-diacyl-sn-glycerolReach from here →
1. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
2. a 3-acyl-sn-glycerol + an acyl-CoA = a 1,3-diacyl-sn-glycerol + CoA
Catalysed by LPGAT1, MOGAT1One of 3 routes
a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphocholineReach from here →
1. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
2. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphocholine + CoA
Catalysed by LPGAT1, LPCAT2, LPCAT1
a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamineReach from here →
1. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
2. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by LPGAT1, LPCAT4
a 1-hexadecanoyl-2-acyl-sn-glycero-3-phosphocholineReach from here →
1. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
2. 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + a 2-acyl-sn-glycero-3-phosphocholine = a 1-hexadecanoyl-2-acyl-sn-glycero-3-phosphocholine + 2-hexadecanoyl-sn-glycero-3-phosphocholine
Catalysed by LPGAT1, PLAAT1
a fatty acyl-CoAReach from here →
1. a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1-acyl-sn-glycero-3-phosphocholine + a fatty acid + H(+)
2. a fatty acid + ATP + CoA = a fatty acyl-CoA + AMP + diphosphate
Catalysed by PLA2G10, PLA2G6, PLA2G1B, PLA2G4B and 27 more
a 1-(9Z-octadecenoyl)-2-acyl-sn-glycero-3-phosphocholineReach from here →
1. an N-acylsphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sphingomyelin + a 1,2-diacyl-sn-glycerol
2. 1-(9Z-octadecenoyl)-2-acyl-sn-3-glycerol + a sphingomyelin = a 1-(9Z-octadecenoyl)-2-acyl-sn-glycero-3-phosphocholine + an N-acylsphing-4-enine
Catalysed by SGMS1, SGMS2
(5Z)-tetradecenoyl-CoAReach from here →
1. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
2. acyl-CoA pool formation and breakdown
Catalysed by LPGAT1cytosol
N,1-diacyl-sn-glycero-3-phosphoethanolamineReach from here →
1. a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + a 1,2-diacyl-sn-glycero-3-phosphocholine = an N-acyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine + a 2-acyl-sn-glycero-3-phosphocholine + H(+)
2. an N-acyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine + H2O = N,1-diacyl-sn-glycero-3-phosphoethanolamine + a fatty acid + H(+)
Catalysed by PLA2G4E, PLAAT5, PLAAT2, ABHD4
an N(2)-acyl-L-glutamineReach from here →
1. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
2. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
Catalysed by LPGAT1, GLYATL1B, GLYATL1
(7Z)-hexadecenoyl-CoAReach from here →
1. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
2. acyl-CoA pool formation and breakdown
Catalysed by LPGAT1cytosol
tricosanoyl-CoAReach from here →
1. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
2. acyl-CoA pool formation and breakdown
Catalysed by LPGAT1cytosol
a 3-oxoacyl-CoAReach from here →
1. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
2. an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA
Catalysed by LPGAT1, ACAA1, SCP2, ACAA2 and 1 more

a 1,2-diacyl-sn-glycero-3-phosphocholine

Two steps

Three steps