3,5-diiodo-L-tyrosine

1. 3-iodo-L-tyrosine + iodide + NADP(+) = 3,5-diiodo-L-tyrosine + NADPH + H(+)

Catalysed by IYDOne of 2 routes

1. thyroid peroxidase (3,5-diiodo-L-tyrosine)

Catalysed by TPOcytosolOne of 2 routes

1. thyroid peroxidase (3,5-diiodo-L-tyrosine)

Catalysed by TPOcytosol

1. 2 iodide + L-tyrosine + 2 NADP(+) = 3,5-diiodo-L-tyrosine + 2 NADPH + H(+)

Catalysed by IYD

1. thyroid peroxidase (3,5-diiodo-L-tyrosine)

Catalysed by TPOcytosol

1. 3-iodo-L-tyrosine + iodide + NADP(+) = 3,5-diiodo-L-tyrosine + NADPH + H(+)

Catalysed by IYD

1. thyroid peroxidase (3,5-diiodo-L-tyrosine)
2. 3,3',5'-triiodo-L-thyronine + iodide + A + H(+) = L-thyroxine + AH2

Catalysed by TPO, DIO1, DIO3cytosolOne of 3 routes

1. thyroid peroxidase (3,5-diiodo-L-tyrosine)
2. transport of S-glutathionyl-2-4-dinitrobenzene (cytosol to extracellular)

Catalysed by TPO, SLCO1A2, SLCO1B3cytosol, extracellular spaceOne of 4 routes

1. 2 iodide + L-tyrosine + 2 NADP(+) = 3,5-diiodo-L-tyrosine + 2 NADPH + H(+)
2. L-tyrosine + 2-oxoglutarate = 3-(4-hydroxyphenyl)pyruvate + L-glutamate
3. (2R)-2-hydroxy-3-(4-hydroxyphenyl)propanoate + NAD(+) = 3-(4-hydroxyphenyl)pyruvate + NADH + H(+)

Catalysed by IYD, TAT, MDH1

1. 3-iodo-L-tyrosine + iodide + NADP(+) = 3,5-diiodo-L-tyrosine + NADPH + H(+)
2. transport of chloride and iodide (cytosol to extracellular)
3. Carnitine Transport by Atb0

Catalysed by