Compound
L-thyroxine sulfate
A thyroxine sulfate(1−) that has L-configuration. The major microspecies at pH 7.3.
Definition from ChEBI (CHEBI:176512), read 2026-09-23. CC BY 4.0.
Structure
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- Class
- Organic compound, anion
- Formula
- C15H10I4NO7S
- Mass
- 855.928 g/mol
- Charge
- -1
- InChIKey
- QYXIJUZWSSQICT-LBPRGKRZSA-M
- SMILES
- [NH3+][C@@H](Cc1cc(I)c(Oc2cc(I)c(OS(=O)(=O)[O-])c(I)c2)c(I)c1)C(=O)[O-]
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
2 entities
2 entities reached.
0 reported hops2 assembled from the scaffold
What the reference databases state
Chemical structure
- L-thyroxine sulfate has the functional parent L-thyroxineCompoundChEBI CHEBI:176512Inferred only
Statements
3 statements
3 statements · 1 reference database · Subject: L-thyroxine sulfate · Sources: Rhea
- L-thyroxine is converted to L-thyroxine sulfateCompoundRhea RHEA:83575Inferred only
- L-thyroxine sulfate is a substrate of DIO1ProteinRhea RHEA:83835Inferred only
- L-thyroxine sulfate is transported by SLCO1C1ProteinRhea RHEA:73311Inferred only
Reactions
3 reactions
L-thyroxine sulfateL-thyroxine sulfate
Transported by SLCO1C1
Reaction pageDirection not assertedBalanced
Rhea RHEA:73311CC BY 4.0Reference data
L-thyroxine+3'-phosphoadenylyl sulfateL-thyroxine sulfate+adenosine 3',5'-bisphosphate+hydron
Catalysed by SULT1A3 or SULT1A4 or SULT1A1
Reaction pageLeft to rightBalanced
Rhea RHEA:83575CC BY 4.0Reference data
3,3',5'-triiodo-L-thyronine sulfate+iodide+A+hydronL-thyroxine sulfate+AH2
Catalysed by DIO1
Reaction pageRight to leftBalanced
Rhea RHEA:83835CC BY 4.0Reference data
Where it reaches
1 system, 1 region, 1 tissue, 1 transporter route — routes, not measurements: transporters known to carry L-thyroxine sulfate are expressed there, and no source reports it arriving.
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Other names
1 name
Resolves to: L-thyroxine sulfate
- Systematic name
- (2S)-2-azaniumyl-3-{4-[3,5-diiodo-4-(sulfonatooxy)phenoxy]-3,5-diiodophenyl}propanoate