Compound

3-iodo-L-tyrosine

Zwitterionic form of 3-iodo-L-tyrosine having an anionic carboxy group and a protonated amino group; major species at pH 7.3.

Definition from ChEBI (CHEBI:59898), read 2026-09-23. CC BY 4.0.

CHEBI:59898ChEBI

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Structure

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A generated conformer of 3-iodo-L-tyrosine — one low-energy arrangement PubChem computed, not a measured structure. Hydrogens are not drawn; the formula counts them.

Class: Organic compound
Formula: C9H10INO3
Mass: 307.087 g/mol
Charge: 0
InChIKey: UQTZMGFTRHFAAM-ZETCQYMHSA-N
SMILES: [NH3+][C@@H](Cc1ccc(O)c(I)c1)C(=O)[O-]
Look it up: ChEBI PubChem By InChIKey

Identity from ChEBI, geometry from PubChem. Not evidence.

What it touches on the way

Mechanistic reach

2 entities

2 entities reached.

0 reported hops2 assembled from the scaffold

What the reference databases state

Statements

5 statements

5 statements · 2 reference databases · Subject: 3-iodo-L-tyrosine · Sources: Human-GEM, Rhea

Order

3-iodo-L-tyrosine is a substrate of IYDProteinRhea RHEA:27453Inferred only
3-iodo-L-tyrosine is a substrate of IYDProteinRhea RHEA:27457Inferred only
3-iodo-L-tyrosine is a substrate of TPOProteinHuman-GEM MAR06794Inferred only
3-iodo-L-tyrosine is a substrate of TPOProteinHuman-GEM MAR06796Inferred only
3-iodo-L-tyrosine is a substrate of TPOProteinHuman-GEM MAR08543Inferred only

Reactions

10 reactions

diiodine+CHEBI:178953-iodo-L-tyrosine+proton+iodide
Catalysed by TPO
Reaction pageLeft to rightBalancedEC 1.11.1.8GO:0005829
Human-GEM MAR06793CC BY 4.0Reference data
3-iodo-L-tyrosine+diiodine3,5-diiodo-L-tyrosine+proton+iodide
Catalysed by TPO
Reaction pageLeft to rightBalancedEC 1.11.1.8GO:0005829
Human-GEM MAR06794CC BY 4.0Reference data
3,5-diiodo-L-tyrosine+3-iodo-L-tyrosine+hydrogen peroxide2-aminoacrylic acid+2water+3,3',5-triiodo-L-thyronine
Catalysed by TPO
Reaction pageLeft to rightBalancedEC 1.11.1.8GO:0005829
Human-GEM MAR06796CC BY 4.0Reference data
3-iodo-L-tyrosine+diiodine3,5-diiodo-L-tyrosine+proton+iodide
Catalysed by TPO
Reaction pageLeft to rightBalancedEC 1.11.1.8GO:0005829
Human-GEM MAR08543CC BY 4.0Reference data
diiodine+CHEBI:178953-iodo-L-tyrosine+proton+iodide
Catalysed by TPO
Reaction pageLeft to rightBalancedEC 1.11.1.8GO:0005829
Human-GEM MAR08544CC BY 4.0Reference data
3-iodo-L-tyrosine+sodium(1+)3-iodo-L-tyrosine+sodium(1+)
Reaction pageReversibleBalancedGO:0005829, GO:0005615
Human-GEM MAR11890CC BY 4.0Reference data
3-iodo-L-tyrosine
Reaction pageReversibleBalance undeterminableGO:0005615
Human-GEM MAR11891CC BY 4.0Reference data
iodide+L-tyrosine+NADP(3-)3-iodo-L-tyrosine+NADPH(4-)
Catalysed by IYD
Reaction pageRight to leftBalance undeterminable
Rhea RHEA:27453CC BY 4.0Reference data
3-iodo-L-tyrosine+iodide+NADP(3-)3,5-diiodo-L-tyrosine+NADPH(4-)+hydron
Catalysed by IYD
Reaction pageRight to leftBalance undeterminable
Rhea RHEA:27457CC BY 4.0Reference data
3-iodo-L-tyrosine3-iodo-L-tyrosine
Transported by SLC43A1 or SLC16A2 or SLC7A5 or SLC43A2 or SLC7A8
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:82883CC BY 4.0Reference data

Other names

1 name

Resolves to: 3-iodo-L-tyrosine

Systematic name: (2S)-2-azaniumyl-3-(4-hydroxy-3- iodophenyl)propanoate