1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

490 compounds within 3 steps: 15 in 1, 84 in 2, 391 in 3

Three steps

AReach from here →
1. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + choline + H(+)
2. choline + A = betaine aldehyde + AH2
3. A + NADH + H(+) = AH2 + NAD(+)
Catalysed by ENPP2, GDPD1, CHDH, AIFM1 and 1 moreOne of 70 routes
(5E)-tetradecenoyl-(R)-carnitineReach from here →
1. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + (9Z)-octadecenoate + H(+)
2. Utilized Transport
3. carnitine O-palmitoyltransferase ((9E)-tetradecenoyl-CoA)
Catalysed by PNPLA7, ASPG, PNPLA6, CPT1A and 2 moreendoplasmic reticulum, cytosolOne of 7 routes
(18S)-hydroxy-(5Z,8Z,11Z,14Z,16E)-eicosapentaenoateReach from here →
1. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + choline + H(+)
2. choline + A = betaine aldehyde + AH2
3. (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + AH2 + O2 = (18S)-hydroxy-(5Z,8Z,11Z,14Z,16E)-eicosapentaenoate + A + H2O
Catalysed by ENPP2, GDPD1, CHDH, PTGS2
(15S)-hydroxy-(5Z,8Z,11Z,13E,17Z)-eicosapentaenoateReach from here →
1. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + choline + H(+)
2. choline + A = betaine aldehyde + AH2
3. (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + AH2 + O2 = (15S)-hydroxy-(5Z,8Z,11Z,13E,17Z)-eicosapentaenoate + A + H2O
Catalysed by ENPP2, GDPD1, CHDH, PTGS2
prostaglandin H3Reach from here →
1. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + choline + H(+)
2. choline + A = betaine aldehyde + AH2
3. prostaglandin G3 + AH2 = prostaglandin H3 + A + H2O
Catalysed by ENPP2, GDPD1, CHDH, PTGS2
1-(9Z-octadecenoyl)-3-(9Z,12Z-octadecadienoyl)-glycerolReach from here →
1. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + (9Z)-octadecenoate + H(+)
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. 1-(9Z,12Z-octadecadienoyl)-glycerol + (9Z)-octadecenoyl-CoA = 1-(9Z-octadecenoyl)-3-(9Z,12Z-octadecadienoyl)-glycerol + CoA
Catalysed by PNPLA7, ASPG, PNPLA6, SLC27A2 and 9 more
13-hydroxy-(9Z,11E)-octadecadienoateReach from here →
1. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + choline + H(+)
2. choline + A = betaine aldehyde + AH2
3. (9Z,12Z)-octadecadienoate + AH2 + O2 = 13-hydroxy-(9Z,11E)-octadecadienoate + A + H2O
Catalysed by ENPP2, GDPD1, CHDH, PTGS2
9-hydroxy-(10E,12Z)-octadecadienoateReach from here →
1. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + choline + H(+)
2. choline + A = betaine aldehyde + AH2
3. (9Z,12Z)-octadecadienoate + AH2 + O2 = 9-hydroxy-(10E,12Z)-octadecadienoate + A + H2O
Catalysed by ENPP2, GDPD1, CHDH, PTGS2
2,4-dinitrophenyl-S-glutathioneReach from here →
1. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + choline + H(+)
2. Acetyl-CoA:choline O-acetyltransferase
3. transport of acetylcholine (cytosol to extracellular)
Catalysed by ENPP2, GDPD1, CHAT, SLCO1B3cytosol, extracellular spaceOne of 2 routes
N-(9Z-octadecenoyl)glycineReach from here →
1. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + (9Z)-octadecenoate + H(+)
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. (9Z)-octadecenoyl-CoA + glycine = N-(9Z-octadecenoyl)glycine + CoA + H(+)
Catalysed by PNPLA7, ASPG, PNPLA6, SLC27A2 and 9 more
9-(9Z-octadecenoyloxy)-octadecanoateReach from here →
1. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + (9Z)-octadecenoate + H(+)
2. 1,2-di-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+) = 1,2,3-tri-(9Z-octadecenoyl)-glycerol + H2O
3. 1,2,3-tri-(9Z-octadecenoyl)-glycerol + 9-hydroxy-octadecanoate = 9-(9Z-octadecenoyloxy)-octadecanoate + 2,3-di-(9Z)-octadecenoyl-sn-glycerol
Catalysed by PNPLA7, ASPG, PNPLA6, DGAT1 and 4 more
9-hydroxy-octadecanoateReach from here →
1. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + (9Z)-octadecenoyl-CoA = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA
2. 1-hexadecanoyl-sn-glycerol + 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine = 1-hexadecanoyl-3-(9Z)-octadecenoyl-sn-glycerol + (9Z-octadecenoyl)-sn-glycero-3-phosphocholine
3. 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + 9-hydroxy-octadecanoate = 1-hexadecanoyl-3-(9Z)-octadecenoyl-sn-glycerol + 9-(9Z-octadecenoyloxy)-octadecanoate
Catalysed by LPCAT3, AGPAT5, PLA2G15, PNPLA2
(13R)-hydroxy-(9Z,11E)-octadecadienoateReach from here →
1. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + choline + H(+)
2. choline + A = betaine aldehyde + AH2
3. (9Z,12Z)-octadecadienoate + AH2 + O2 = (13R)-hydroxy-(9Z,11E)-octadecadienoate + A + H2O
Catalysed by ENPP2, GDPD1, CHDH, PTGS1 and 1 more
2-[(11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoyl]-sn-glycero-3-phosphocholineReach from here →
1. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + choline + H(+)
2. choline + A = betaine aldehyde + AH2
3. 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + AH2 + O2 = 2-[(11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoyl]-sn-glycero-3-phosphocholine + A + H2O
Catalysed by ENPP2, GDPD1, CHDH, PTGS2
2-[(15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-sn-glycero-3-phosphocholineReach from here →
1. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + choline + H(+)
2. choline + A = betaine aldehyde + AH2
3. 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + AH2 + O2 = 2-[(15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-sn-glycero-3-phosphocholine + A + H2O
Catalysed by ENPP2, GDPD1, CHDH, PTGS2
2-[(15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-sn-glycero-3-phosphocholineReach from here →
1. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + choline + H(+)
2. choline + A = betaine aldehyde + AH2
3. 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + AH2 + O2 = 2-[(15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-sn-glycero-3-phosphocholine + A + H2O
Catalysed by ENPP2, GDPD1, CHDH, PTGS2
2-(prostaglandin H2)-sn-glycero-3-phosphoethanolamineReach from here →
1. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + choline + H(+)
2. choline + A = betaine aldehyde + AH2
3. 2-(prostaglandin G2)-sn-glycero-3-phosphoethanolamine + AH2 = 2-(prostaglandin H2)-sn-glycero-3-phosphoethanolamine + A + H2O
Catalysed by ENPP2, GDPD1, CHDH, PTGS2
2-(prostaglandin H2)-sn-glycero-3-phosphocholineReach from here →
1. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + choline + H(+)
2. choline + A = betaine aldehyde + AH2
3. 2-(prostaglandin G2)-sn-glycero-3-phosphocholine + AH2 = 2-(prostaglandin H2)-sn-glycero-3-phosphocholine + A + H2O
Catalysed by ENPP2, GDPD1, CHDH, PTGS2
1-hexadecanoyl-2-heptanoyl-sn-glycero-3-phosphocholineReach from here →
1. 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine
2. 1-hexadecanoyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + CoA
3. 1,2-diheptanoyl-sn-glycero-3-phosphocholine + 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-heptanoyl-sn-glycero-3-phosphocholine + 1-heptanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine
Catalysed by TAFAZZIN, PRDX6, LPCAT3, LPCAT1 and 1 more
1-heptanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine
2. 1-hexadecanoyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + CoA
3. 1,2-diheptanoyl-sn-glycero-3-phosphocholine + 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-heptanoyl-sn-glycero-3-phosphocholine + 1-heptanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine
Catalysed by TAFAZZIN, PRDX6, LPCAT3, LPCAT1 and 1 more
1-O-(1Z-octadecenoyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-N-hexadecanoyl-ethanolamineReach from here →
1. 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine
2. 1-hexadecanoyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + CoA
3. 1-(1Z-octadecenyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine = 1-O-(1Z-octadecenoyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-N-hexadecanoyl-ethanolamine + 2-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)
Catalysed by TAFAZZIN, PRDX6, LPCAT3, LPCAT1 and 1 more
1-O-(9Z-octadecenyl)-2,3-di-(9Z-octadecenoyl)glycerolReach from here →
1. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + (9Z)-octadecenoate + H(+)
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. 1-O-(9Z-octadecyl)-3-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoyl-CoA = 1-O-(9Z-octadecenyl)-2,3-di-(9Z-octadecenoyl)glycerol + CoA
Catalysed by PNPLA7, ASPG, PNPLA6, SLC27A2 and 10 more
beta-D-glucosyl-N-(9Z-octadecenoyl)-sphing-4E-enineReach from here →
1. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + (9Z)-octadecenoate + H(+)
2. N-(9Z-octadecenoyl)-sphing-4-enine + H2O = sphing-4-enine + (9Z)-octadecenoate
3. beta-D-glucosyl-N-(9Z-octadecenoyl)-sphing-4E-enine + cholesterol = N-(9Z-octadecenoyl)-sphing-4-enine + cholesteryl 3-beta-D-glucoside
Catalysed by PNPLA7, ASPG, PNPLA6, ASAH1 and 6 more
3-(9Z-octadecenoyl)-sn-glycero-1-phospho-(1'-sn-glycerol)Reach from here →
1. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-(9Z-octadecenoyl)-sn-glycerol + phosphocholine + H(+)
2. 3-lyso-sn-glycero-1-phospho-(3'-(9Z-octadecenoyl)-1'-sn-glycerol) + 1-(9Z-octadecenoyl)-sn-glycerol = 3-(9Z-octadecenoyl)-sn-glycero-1-phospho-(3'-(9Z-octadecenoyl)-1'-sn-glycerol) + glycerol
3. 3-(9Z-octadecenoyl)-sn-glycero-1-phospho-(3'-(9Z-octadecenoyl)-1'-sn-glycerol) + H2O = 3-(9Z-octadecenoyl)-sn-glycero-1-phospho-(1'-sn-glycerol) + (9Z)-octadecenoate + H(+)
Catalysed by ENPP6, ABHD12, PLD3, PLD4 and 1 more
1-O-(1Z-alkenyl)-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamineReach from here →
1. 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine
2. (9Z,12Z)-octadecadienoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + CoA
3. 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine = 1-O-(1Z-alkenyl)-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine + 1-hexadecanoyl-sn-glycero-3-phosphocholine
Catalysed by TAFAZZIN, LPCAT3, MBOAT2, LPCAT1 and 1 more
(7Z)-octadecenoyl-CoAReach from here →
1. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + choline + H(+)
2. Acetyl-CoA:choline O-acetyltransferase
3. carnitine O-palmitoyltransferase ((7Z)-octadecenoyl-CoA)
Catalysed by ENPP2, GDPD1, CHAT, CPT1A and 2 morecytosolOne of 3 routes
CHEBI:15345Reach from here →
1. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + choline + H(+)
2. Acetyl-CoA:choline O-acetyltransferase
3. Acetoacetate:CoA ligase (AMP-forming)
Catalysed by ENPP2, GDPD1, CHAT, AACScytosolOne of 2 routes
CHEBI:15380Reach from here →
1. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + choline + H(+)
2. Acetyl-CoA:choline O-acetyltransferase
3. 5-aminolevulinate synthase (2-amino-3-oxoadipate)
Catalysed by ENPP2, GDPD1, CHAT, ALAS1 and 1 morecytosol, mitochondrial matrixOne of 8 routes
CHEBI:15477Reach from here →
1. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + choline + H(+)
2. Acetyl-CoA:choline O-acetyltransferase
3. glycine N-acyltransferase (2-methylbutyryl-CoA)
Catalysed by ENPP2, GDPD1, CHAT, GLYAT and 2 morecytosol, mitochondrial matrixOne of 2 routes
2-methylcrotonoyl-CoAReach from here →
1. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + choline + H(+)
2. Acetyl-CoA:choline O-acetyltransferase
3. Production of Tiglylcarnitine
Catalysed by ENPP2, GDPD1, CHAT, CPT1A and 1 morecytosolOne of 2 routes
isobutyryl-CoAReach from here →
1. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + choline + H(+)
2. Acetyl-CoA:choline O-acetyltransferase
3. acetyl-CoA C-acyltransferase (3-oxo-4-methyl-pentanoyl-CoA)
Catalysed by ENPP2, GDPD1, CHAT, HADHA and 2 morecytosol, mitochondrial matrixOne of 3 routes
3-methylbut-2-enoyl-CoAReach from here →
1. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + choline + H(+)
2. Acetyl-CoA:choline O-acetyltransferase
3. glycine-N-acyltransferase (3-methylcrotonoylglycine)
Catalysed by ENPP2, GDPD1, CHAT, GLYATcytosol, mitochondrial matrix
isovaleryl-CoAReach from here →
1. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + choline + H(+)
2. Acetyl-CoA:choline O-acetyltransferase
3. glycine N-acyltransferase (isovalerylglycine)
Catalysed by ENPP2, GDPD1, CHAT, GLYAT and 2 morecytosol, mitochondrial matrixOne of 3 routes
arachidonoyl-CoAReach from here →
1. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + choline + H(+)
2. Acetyl-CoA:choline O-acetyltransferase
3. Arachidonate:CoA ligase (AMP-forming)
Catalysed by ENPP2, GDPD1, CHAT, SLC27A2 and 7 morecytosolOne of 11 routes
CHEBI:15519Reach from here →
1. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + choline + H(+)
2. Acetyl-CoA:choline O-acetyltransferase
3. propanoyl-CoA C-acyltransferase
Catalysed by ENPP2, GDPD1, CHAT, ACAA1 and 2 morecytosol, peroxisomeOne of 2 routes
palmitoyl-CoAReach from here →
1. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + choline + H(+)
2. Acetyl-CoA:choline O-acetyltransferase
3. Palmitate:CoA ligase (AMP-forming)
Catalysed by ENPP2, GDPD1, CHAT, SLC27A2 and 7 morecytosolOne of 11 routes
phenylacetyl-CoAReach from here →
1. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + choline + H(+)
2. Acetyl-CoA:choline O-acetyltransferase
3. Phenylacetate:CoA ligase
Catalysed by ENPP2, GDPD1, CHATcytosolOne of 3 routes
propionyl-CoAReach from here →
1. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + choline + H(+)
2. Acetyl-CoA:choline O-acetyltransferase
3. Propanoate:CoA ligase (AMP-forming)
Catalysed by ENPP2, GDPD1, CHAT, ACSS3 and 2 morecytosolOne of 45 routes
L-leucineReach from here →
1. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + choline + H(+)
2. transport of chloride and choline (cytosol to extracellular)
3. transport of chloride and leucine (cytosol to extracellular)
Catalysed by ENPP2, GDPD1, SLC5A7, SLC6A14extracellular space, cytosolOne of 3 routes
1-(10Z-heptadecenoyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamineReach from here →
1. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + (9Z)-octadecenoate + H(+)
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. 1-(10Z-heptadecenoyl)-sn-glycero-3-phosphoethanolamine + (9Z)-octadecenoyl-CoA = 1-(10Z-heptadecenoyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by PNPLA7, ASPG, PNPLA6, SLC27A2 and 8 more
CHEBI:15650Reach from here →
1. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + choline + H(+)
2. Acetyl-CoA:choline O-acetyltransferase
3. N-acetyl-LTE4 to leukotriene E4 conversion
Catalysed by ENPP2, GDPD1, CHAT, ZDHHC11B and 31 morecytosolOne of 2 routes
S-(9Z-octadecenoyl)-4'-phosphopantetheineReach from here →
1. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + (9Z)-octadecenoate + H(+)
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. (9Z)-octadecenoyl-CoA + H2O = S-(9Z-octadecenoyl)-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)
Catalysed by PNPLA7, ASPG, PNPLA6, SLC27A2 and 8 more
CHEBI:15727Reach from here →
1. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + choline + H(+)
2. Acetyl-CoA:choline O-acetyltransferase
3. N-alpha-acetyltransferase 10, NatA catalytic subunit (acetylcarnosine)
Catalysed by ENPP2, GDPD1, CHAT, NAA10cytosol
CHEBI:15746Reach from here →
1. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + choline + H(+)
2. Acetyl-CoA:choline O-acetyltransferase
3. diamine N-acetyltransferase (N1-acetylspermine)
Catalysed by ENPP2, GDPD1, CHAT, SAT1 and 1 morecytosolOne of 2 routes
hexadecanoic acidReach from here →
1. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + (9Z)-octadecenoate + H(+)
2. (10Z)-heptadecenoic acid formation
3. (10Z)-heptadecenoic acid formation
Catalysed by PNPLA7, ASPG, PNPLA6cytosol, extracellular spaceOne of 14 routes
a 1-O-alkyl-sn-glycerolReach from here →
1. 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine
2. a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-acetyl-sn-glycero-3-phosphocholine + a 1-O-alkyl-sn-glycero-3-phosphocholine
3. a 1-O-alkyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycerol + phosphocholine + H(+)
Catalysed by TAFAZZIN, LCAT, ENPP6
CHEBI:15971Reach from here →
1. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + choline + H(+)
2. transport of chloride and choline (cytosol to extracellular)
3. transport of chloride and histidine (cytosol to extracellular)
Catalysed by ENPP2, GDPD1, SLC5A7, SLC6A14extracellular space, cytosol
CHEBI:16108Reach from here →
1. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + (9Z)-octadecenoate + H(+)
2. sn-Glycero-3-phosphocholine glycerophosphohydrolase
3. sn-Glycerol-3-phosphate:(acceptor) 2-oxidoreductase
Catalysed by PNPLA7, ASPG, PNPLA6, GPCPD1 and 1 morecytosol, mitochondrial matrixOne of 2 routes
cholesterolReach from here →
1. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + (9Z)-octadecenoate + H(+)
2. N-(9Z-octadecenoyl)-sphing-4-enine + H2O = sphing-4-enine + (9Z)-octadecenoate
3. beta-D-glucosyl-N-(9Z-octadecenoyl)-sphing-4E-enine + cholesterol = N-(9Z-octadecenoyl)-sphing-4-enine + cholesteryl 3-beta-D-glucoside
Catalysed by PNPLA7, ASPG, PNPLA6, ASAH1 and 6 more
sulfateReach from here →
1. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + choline + H(+)
2. transport of chloride and choline (cytosol to extracellular)
3. transport of chloride and sulfate (cytosol to extracellular)
Catalysed by ENPP2, GDPD1, SLC5A7, SLC26A6extracellular space, cytosol